ID V8PGS7_OPHHA Unreviewed; 372 AA.
AC V8PGS7;
DT 19-FEB-2014, integrated into UniProtKB/TrEMBL.
DT 19-FEB-2014, sequence version 1.
DT 22-FEB-2023, entry version 18.
DE SubName: Full=Complement C1q tumor necrosis factor-related protein 4 {ECO:0000313|EMBL:ETE73769.1};
DE Flags: Fragment;
GN Name=C1QTNF4 {ECO:0000313|EMBL:ETE73769.1};
GN ORFNames=L345_00382 {ECO:0000313|EMBL:ETE73769.1};
OS Ophiophagus hannah (King cobra) (Naja hannah).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Toxicofera;
OC Serpentes; Colubroidea; Elapidae; Elapinae; Ophiophagus.
OX NCBI_TaxID=8665 {ECO:0000313|EMBL:ETE73769.1, ECO:0000313|Proteomes:UP000018936};
RN [1] {ECO:0000313|EMBL:ETE73769.1, ECO:0000313|Proteomes:UP000018936}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Blood {ECO:0000313|EMBL:ETE73769.1};
RX PubMed=24297900; DOI=10.1073/pnas.1314702110;
RA Vonk F.J., Casewell N.R., Henkel C.V., Heimberg A.M., Jansen H.J.,
RA McCleary R.J., Kerkkamp H.M., Vos R.A., Guerreiro I., Calvete J.J.,
RA Wuster W., Woods A.E., Logan J.M., Harrison R.A., Castoe T.A.,
RA de Koning A.P., Pollock D.D., Yandell M., Calderon D., Renjifo C.,
RA Currier R.B., Salgado D., Pla D., Sanz L., Hyder A.S., Ribeiro J.M.,
RA Arntzen J.W., van den Thillart G.E., Boetzer M., Pirovano W., Dirks R.P.,
RA Spaink H.P., Duboule D., McGlinn E., Kini R.M., Richardson M.K.;
RT "The king cobra genome reveals dynamic gene evolution and adaptation in the
RT snake venom system.";
RL Proc. Natl. Acad. Sci. U.S.A. 110:20651-20656(2013).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ETE73769.1}.
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DR EMBL; AZIM01000039; ETE73769.1; -; Genomic_DNA.
DR AlphaFoldDB; V8PGS7; -.
DR Proteomes; UP000018936; Unassembled WGS sequence.
DR Gene3D; 2.60.120.40; -; 2.
DR InterPro; IPR001073; C1q_dom.
DR InterPro; IPR008983; Tumour_necrosis_fac-like_dom.
DR PANTHER; PTHR22923; CEREBELLIN-RELATED; 1.
DR PANTHER; PTHR22923:SF107; COMPLEMENT C1Q TUMOR NECROSIS FACTOR-RELATED PROTEIN 4; 1.
DR Pfam; PF00386; C1q; 2.
DR PRINTS; PR00007; COMPLEMNTC1Q.
DR SMART; SM00110; C1Q; 2.
DR SUPFAM; SSF49842; TNF-like; 2.
DR PROSITE; PS50871; C1Q; 2.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000018936};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..23
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 24..372
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004771461"
FT DOMAIN 29..168
FT /note="C1q"
FT /evidence="ECO:0000259|PROSITE:PS50871"
FT DOMAIN 214..358
FT /note="C1q"
FT /evidence="ECO:0000259|PROSITE:PS50871"
FT REGION 209..237
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:ETE73769.1"
SQ SEQUENCE 372 AA; 42205 MW; BEC304DA51E409AF CRC64;
MTQRKDQISF GLLFHLACSF VYGFPADSGT EFRSAFSVAR TSSMEGSTEM VITFDKVYVN
IGDDFDPKAG LFRCRIPGAY YFSFTVGKYP KKNLSVMLMR NKNEVQAIVY DEHHRKERKV
ASQSAMLQLD YGDTVWLRLH GDPKYALYSN VGPYTTFNGY LIYPDTSSYF QNRVGSPELG
KEPSQPPSHV IQQLSINQNQ VSERLLLSDE PARPQDPRSA FSAARSESLL GSDEKQTQHE
PITFDTEFVN IGNDFNFSTG IFACRVPGAY YFSFTIGKMP FKTMSVKLMK NHNEVQAMIY
DDNHSKRREM QSQSIMLPLQ SGDIVWLYSH QHDGYGAYSN HGKYITFTGF LVYPETKTKF
SSDSNIPPGS NL
//
