ID   V9DXA6_PHYPR            Unreviewed;       910 AA.
AC   V9DXA6;
DT   19-FEB-2014, integrated into UniProtKB/TrEMBL.
DT   19-FEB-2014, sequence version 1.
DT   27-MAR-2024, entry version 26.
DE   RecName: Full=EGF-like domain-containing protein {ECO:0000259|PROSITE:PS50026};
GN   ORFNames=F443_21689 {ECO:0000313|EMBL:ETI31316.1};
OS   Phytophthora parasitica P1569.
OC   Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC   Phytophthora.
OX   NCBI_TaxID=1317065 {ECO:0000313|EMBL:ETI31316.1, ECO:0000313|Proteomes:UP000018721};
RN   [1] {ECO:0000313|EMBL:ETI31316.1, ECO:0000313|Proteomes:UP000018721}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=P1569 {ECO:0000313|EMBL:ETI31316.1,
RC   ECO:0000313|Proteomes:UP000018721};
RG   The Broad Institute Genomics Platform;
RA   Russ C., Tyler B., Panabieres F., Shan W., Tripathy S., Grunwald N.,
RA   Machado M., Johnson C.S., Arredondo F., Hong C., Coffey M., Young S.K.,
RA   Zeng Q., Gargeya S., Fitzgerald M., Abouelleil A., Alvarado L.,
RA   Chapman S.B., Gainer-Dewar J., Goldberg J., Griggs A., Gujja S., Hansen M.,
RA   Howarth C., Imamovic A., Ireland A., Larimer J., McCowan C., Murphy C.,
RA   Pearson M., Poon T.W., Priest M., Roberts A., Saif S., Shea T., Sykes S.,
RA   Wortman J., Nusbaum C., Birren B.;
RT   "The Genome Sequence of Phytophthora parasitica P1569.";
RL   Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC       feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00076}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:ETI31316.1}.
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DR   EMBL; ANIZ01003793; ETI31316.1; -; Genomic_DNA.
DR   AlphaFoldDB; V9DXA6; -.
DR   EnsemblProtists; ETI31316; ETI31316; F443_21689.
DR   eggNOG; ENOG502SKK0; Eukaryota.
DR   HOGENOM; CLU_319456_0_0_1; -.
DR   OrthoDB; 77118at2759; -.
DR   Proteomes; UP000018721; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   CDD; cd00054; EGF_CA; 2.
DR   Gene3D; 2.60.120.380; -; 1.
DR   Gene3D; 2.10.25.10; Laminin; 1.
DR   InterPro; IPR000742; EGF-like_dom.
DR   InterPro; IPR013111; EGF_extracell.
DR   PANTHER; PTHR24033; EGF-LIKE DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF07974; EGF_2; 1.
DR   SMART; SM00181; EGF; 4.
DR   SUPFAM; SSF57196; EGF/Laminin; 1.
DR   PROSITE; PS00022; EGF_1; 3.
DR   PROSITE; PS01186; EGF_2; 2.
DR   PROSITE; PS50026; EGF_3; 3.
PE   4: Predicted;
KW   Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW   ProRule:PRU00076};
KW   EGF-like domain {ECO:0000256|ARBA:ARBA00022536, ECO:0000256|PROSITE-
KW   ProRule:PRU00076}; Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000018721};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        815..837
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          135..170
FT                   /note="EGF-like"
FT                   /evidence="ECO:0000259|PROSITE:PS50026"
FT   DOMAIN          414..448
FT                   /note="EGF-like"
FT                   /evidence="ECO:0000259|PROSITE:PS50026"
FT   DOMAIN          597..634
FT                   /note="EGF-like"
FT                   /evidence="ECO:0000259|PROSITE:PS50026"
FT   REGION          848..910
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   DISULFID        160..169
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT   DISULFID        438..447
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT   DISULFID        624..633
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
SQ   SEQUENCE   910 AA;  97954 MW;  E885BC79BD9DCF74 CRC64;
     MTLLTEDGVS VTVGSKQYKF FKFALDASSY DVTFIVEYPS GTHATTDVDL YGSFDEQFPT
     ALTASSIRFS STNDAKVSDE INLCGSLGVF PRGINSTSRI CTKATEAYTQ AVPGYFYLSL
     LGFSTGNSLV RLRVETDKCR GVTCSGHGSC GRNKPGVCTC DRYWSGDDCS VPKCGPDCQD
     LGTCSDATTW TDSTTTVSIG INSLRNTSEC YGNGVCQVTG NHPVCVCDEA FTFSPPTTSA
     QALCKELVLS VAYIEHFTGP FRMEAGLLDL QIERGNWALY TITVKDEWEV LVVNLDKISS
     DGDATLFIRR ETLPTILLTA SSSSSSIQFT DVGGWATAAS TRKIVLSRST STLSSGLYYI
     GVYNSEYARG SLDYRLTVNA ADDCQTSTLV SSFNAVMEEN NATLSDSGST DLSTDDDTVG
     VCLNGGVCST LSSELCTCTD GYSGRYCSLQ PTRIVLSKPF VSSTNVAYES AEYLTLAVGE
     WVYFSFDVND SAAKAVEFSL LIHNDIAEAE TPVRPLLLVR GPSDAGFPSL AISSLQDFDA
     VAQRSNKQTV AVAVTTACSY AATRSDCFKV AVHNRVVSGS PLRFQLQAAV YSSTSSTLAS
     CGDTESCHGH GQCVVKDGTP SCQCETGWSG ISCNSPKGFE LIQLWSAMEN VTMLCSTCNA
     SFTLTRGQVM MFRVPEPLRV GVGLRLTLQS VEQATGGVTP SVYVSEVLPR SLYDFTYISL
     ASEDTSTKAQ AVEIPNASFS GDFWVVVHTD YPSTNGTTQL TVSARRRLVN SEASSFQLVA
     EQYETSDADA YSSLLTDQSF GHAIFKWVFR SPAGIAVFTF AVTLLVTALC FCVYRVARAP
     ENQDKVLARL YPPQNERGGL RTPGTDNKRT SGAVVVDIHE SSKETPTSKA TQGRPSTGRI
     LRKKAEQSNK
//