ID V9EP10_PHYPR Unreviewed; 1020 AA.
AC V9EP10;
DT 19-FEB-2014, integrated into UniProtKB/TrEMBL.
DT 19-FEB-2014, sequence version 1.
DT 08-NOV-2023, entry version 27.
DE RecName: Full=TNFR-Cys domain-containing protein {ECO:0000259|PROSITE:PS50050};
GN ORFNames=F443_14012 {ECO:0000313|EMBL:ETI40646.1};
OS Phytophthora parasitica P1569.
OC Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC Phytophthora.
OX NCBI_TaxID=1317065 {ECO:0000313|EMBL:ETI40646.1, ECO:0000313|Proteomes:UP000018721};
RN [1] {ECO:0000313|EMBL:ETI40646.1, ECO:0000313|Proteomes:UP000018721}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=P1569 {ECO:0000313|EMBL:ETI40646.1,
RC ECO:0000313|Proteomes:UP000018721};
RG The Broad Institute Genomics Platform;
RA Russ C., Tyler B., Panabieres F., Shan W., Tripathy S., Grunwald N.,
RA Machado M., Johnson C.S., Arredondo F., Hong C., Coffey M., Young S.K.,
RA Zeng Q., Gargeya S., Fitzgerald M., Abouelleil A., Alvarado L.,
RA Chapman S.B., Gainer-Dewar J., Goldberg J., Griggs A., Gujja S., Hansen M.,
RA Howarth C., Imamovic A., Ireland A., Larimer J., McCowan C., Murphy C.,
RA Pearson M., Poon T.W., Priest M., Roberts A., Saif S., Shea T., Sykes S.,
RA Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Phytophthora parasitica P1569.";
RL Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00206}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ETI40646.1}.
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DR EMBL; ANIZ01002432; ETI40646.1; -; Genomic_DNA.
DR AlphaFoldDB; V9EP10; -.
DR EnsemblProtists; ETI40646; ETI40646; F443_14012.
DR eggNOG; ENOG502RAH2; Eukaryota.
DR HOGENOM; CLU_008389_0_0_1; -.
DR OrthoDB; 66446at2759; -.
DR Proteomes; UP000018721; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:InterPro.
DR GO; GO:0004930; F:G protein-coupled receptor activity; IEA:InterPro.
DR Gene3D; 2.60.40.2030; -; 4.
DR Gene3D; 2.10.50.10; Tumor Necrosis Factor Receptor, subunit A, domain 2; 2.
DR InterPro; IPR026919; ADGRV1.
DR InterPro; IPR038081; CalX-like_sf.
DR InterPro; IPR003644; Calx_beta.
DR InterPro; IPR001368; TNFR/NGFR_Cys_rich_reg.
DR PANTHER; PTHR46682; ADHESION G-PROTEIN COUPLED RECEPTOR V1; 1.
DR PANTHER; PTHR46682:SF1; ADHESION G-PROTEIN COUPLED RECEPTOR V1; 1.
DR Pfam; PF03160; Calx-beta; 4.
DR Pfam; PF00020; TNFR_c6; 1.
DR SMART; SM00237; Calx_beta; 3.
DR SMART; SM00208; TNFR; 2.
DR SUPFAM; SSF141072; CalX-like; 4.
DR PROSITE; PS50050; TNFR_NGFR_2; 2.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|PROSITE-ProRule:PRU00206};
KW Reference proteome {ECO:0000313|Proteomes:UP000018721};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..18
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 19..1020
FT /note="TNFR-Cys domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004774488"
FT REPEAT 835..878
FT /note="TNFR-Cys"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00206"
FT DOMAIN 835..878
FT /note="TNFR-Cys"
FT /evidence="ECO:0000259|PROSITE:PS50050"
FT REPEAT 883..926
FT /note="TNFR-Cys"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00206"
FT DOMAIN 883..926
FT /note="TNFR-Cys"
FT /evidence="ECO:0000259|PROSITE:PS50050"
FT DISULFID 857..870
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00206"
FT DISULFID 860..878
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00206"
FT DISULFID 905..918
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00206"
FT DISULFID 908..926
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00206"
SQ SEQUENCE 1020 AA; 109571 MW; D09DC99C87AE3254 CRC64;
MTILRHSLTF LLVTIIAAGD IFDRLRGVVA IATSGRFQFS QAVYSTTEDF GVASITIQRS
LGSDGRAAVY ISTIPGVGNA VAGRDFKPLY NVSLMWQDGE DFEQALYVPV YNDGKPQESP
KTFMLKMHDA VGAEINLARN QTQVVLVPPA NLVPGSFTFQ TATVTVAEGN TLTVPVLWVA
GTTSMASVKF EVVCKSACFP TDFVLVSPAT HLLEWKRDDY PASATIRWQN IVLQVLNDEL
YEQIESFSIR LMVVEPSEDS TIGTGVIADI GEIIVAIDGP NDVRSGMLQF NAECFPDCAS
AKYAVQSGGS ALVIVQRRSG SDGDCSVVVA AQDDTAVAGL DYEPLERELF WKEGDTSDRQ
IVVTSLARAD PRLPSRRIAL VLRNNKGAPI NGAHASTSYV DITSPTSVYL GDVNFAIREP
LESVLRAPDL SFIELASRNT SSKLQLCPST VVTEPGVLSV AIQRNFATFP VPVRVTVKAV
AGTATPGVDY EFLDSVVTWG NGETEAKQVL VKILNPPNYD PYTHLFWLQL SGVTGAIVGD
CNVLEVVLKE VAQRPHLVSF DLDMALGTMT LRMNIPVQAS TLDVTKLLLQ SERVLKNGAT
FKFTPQQTTS SSTDGSTIVL NIGAGDLNSL KRVIGLAKSA NSVFLSTEAG LFRYVVDNCH
STGILACSSD VTVETPRSAA LAVATFIADT LAPTLVGYSL DLPRRLLKLH FSEAVNFITL
KIESLTLAEG EAGIDVYRLS SATTRLFSPQ PDPLSGATLR DANRLPADNT FLTLHLGRSD
VTALSSFGTG QFGITRANTF LGIESSFVAD FAGNPVMAVG PPGKMLQVST ADCSPCPSGS
YLTSSCSDLT DRKCGTCNVC PRNSFALETC RATQDTLCYP CTECRSGQYV AVACSPMTDR
VCAPCTQCTL DEYEVSPCAA GVDRVCRTCN SCTLTAAQQT LCQRSHVWKR LQMRSPFSCP
QPGQQFKTRE EQLQRAKSNL CGSGRCSCVA TGIPGNSNPN GEGFPDDPRC TGPVAYNILV
//
