ID V9FIC3_PHYPR Unreviewed; 2283 AA.
AC V9FIC3;
DT 19-FEB-2014, integrated into UniProtKB/TrEMBL.
DT 19-FEB-2014, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE RecName: Full=HECT-type E3 ubiquitin transferase {ECO:0008006|Google:ProtNLM};
GN ORFNames=F443_05434 {ECO:0000313|EMBL:ETI51235.1};
OS Phytophthora parasitica P1569.
OC Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC Phytophthora.
OX NCBI_TaxID=1317065 {ECO:0000313|EMBL:ETI51235.1, ECO:0000313|Proteomes:UP000018721};
RN [1] {ECO:0000313|EMBL:ETI51235.1, ECO:0000313|Proteomes:UP000018721}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=P1569 {ECO:0000313|EMBL:ETI51235.1,
RC ECO:0000313|Proteomes:UP000018721};
RG The Broad Institute Genomics Platform;
RA Russ C., Tyler B., Panabieres F., Shan W., Tripathy S., Grunwald N.,
RA Machado M., Johnson C.S., Arredondo F., Hong C., Coffey M., Young S.K.,
RA Zeng Q., Gargeya S., Fitzgerald M., Abouelleil A., Alvarado L.,
RA Chapman S.B., Gainer-Dewar J., Goldberg J., Griggs A., Gujja S., Hansen M.,
RA Howarth C., Imamovic A., Ireland A., Larimer J., McCowan C., Murphy C.,
RA Pearson M., Poon T.W., Priest M., Roberts A., Saif S., Shea T., Sykes S.,
RA Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Phytophthora parasitica P1569.";
RL Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ETI51235.1}.
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DR EMBL; ANIZ01000941; ETI51235.1; -; Genomic_DNA.
DR EnsemblProtists; ETI51235; ETI51235; F443_05434.
DR eggNOG; KOG0940; Eukaryota.
DR eggNOG; KOG1729; Eukaryota.
DR HOGENOM; CLU_228648_0_0_1; -.
DR OrthoDB; 55984at2759; -.
DR Proteomes; UP000018721; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd00065; FYVE_like_SF; 1.
DR CDD; cd00201; WW; 2.
DR Gene3D; 2.20.70.10; -; 2.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 2.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR000225; Armadillo.
DR InterPro; IPR001202; WW_dom.
DR InterPro; IPR036020; WW_dom_sf.
DR InterPro; IPR000306; Znf_FYVE.
DR InterPro; IPR017455; Znf_FYVE-rel.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR InterPro; IPR005735; Znf_LSD1.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR23164; EARLY ENDOSOME ANTIGEN 1; 1.
DR PANTHER; PTHR23164:SF30; LD23155P; 1.
DR Pfam; PF01363; FYVE; 1.
DR Pfam; PF00397; WW; 2.
DR Pfam; PF06943; zf-LSD1; 1.
DR SMART; SM00185; ARM; 4.
DR SMART; SM00064; FYVE; 1.
DR SMART; SM00456; WW; 2.
DR SUPFAM; SSF48371; ARM repeat; 3.
DR SUPFAM; SSF57903; FYVE/PHD zinc finger; 1.
DR SUPFAM; SSF51045; WW domain; 2.
DR PROSITE; PS01159; WW_DOMAIN_1; 2.
DR PROSITE; PS50020; WW_DOMAIN_2; 2.
DR PROSITE; PS50178; ZF_FYVE; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000018721};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00091}.
FT DOMAIN 72..105
FT /note="WW"
FT /evidence="ECO:0000259|PROSITE:PS50020"
FT DOMAIN 106..139
FT /note="WW"
FT /evidence="ECO:0000259|PROSITE:PS50020"
FT DOMAIN 360..422
FT /note="FYVE-type"
FT /evidence="ECO:0000259|PROSITE:PS50178"
FT REGION 135..227
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 270..338
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2175..2207
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 147..167
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 187..227
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 270..300
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 323..338
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2175..2194
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2283 AA; 251964 MW; F932BE68B2E6B594 CRC64;
MYAAVVYSSW EVHHCTNSCT LHTCIYLIAT FILIKLFAIV RSCRQHEMGT EKVPFGIVRF
QCQYQKSIAS MSSRHGEWQR VQDAQGRYFY VNHATRETSW HLPSAEPLPP GWEELIDGQG
RLYFVDHNTR TTTWMDPRVA AARRRTRGQS VLSSRPPSRS NIPPMDNARG RSPTYEDPRH
ASVGSAGSRS DAGSNGFVRS RKSSGANLSA GSPSSSGARR DSADQTIRMN TSTLLERYRD
ETNLGDTAVM QTTESTALPA DAEEWFTAHS EDLSRRSSVE KKEPELEQVT DSKEETPSAG
VQEEETAASS SLVEEEKDLA KSGQQQQQEQ RVSGVRGSSF NTGDVQMVLR RYFAPNFVRD
DDSPACRQCG MRFGTFRRRH HCRLCGNVYC ADCTTNKVKL PIEAPSYDKE QPVCTRCFRN
VQAGDFFSIV GLRHKLEDPS STVDDRVEQI MQLSMTLSAG RPETDGNMGL HRVAQLNDVE
AAGGVASFCQ LLTTDVEPLQ QAALEMLANL IELENSAGNE LSAGEAFANS GACAQLVKVM
GNRVMEQQLG RSVRPEVERM ALRLVYHICQ STTCQNALRK AGGGTRLLEL LSVDSPSSLE
MRVEAARCLK RFVQKNGENI TEMTQNKGVA LLCTLLGDFI ELRAGSNLGN SGVEATRDES
HEVAMEAILS TICECIHFAD NGASQVQRGV QQIPADSIHS FVTVLQKGDR VNRMLASQVL
IQVSKEPSLI TILAKEQEFI KEIMWMLDSD EDYTVASEIL CGLCSTMPKQ SLSDTVPGEN
VDDAHEQVLK VIYDLEVFDL VLKKLNACVV GEKQLVGEIT FQRNLLGITM SYSAESAAYV
DYICSRNCVP TLSAFLLSRK ERLIPLCAQT LMNLCEFNPS IFDELYDRNV SDFFHRLLQT
PPDENRLSAL RYFRALVDNK RPFSVGVLDT LFLMASGRDE VLKAGSLDVL AHLSGVKSIG
AVLEPLEEPP TPEIGEMVQK LQERVVGVAY FPVLMTIACS SGDTDMRSNA IKCLSCAVGG
GEELVARMLD QEMLRAFWMG LRRWMDVPAD ELTPVEMQLN KALLQLLYLV LKMASSRIAS
MGEDQVTNLV TVVTEFIVSQ PSRLVMGIRI IRLLIAHAAW KDSFVALYAV ESTSTGLKFL
QALMNGIEQS SVTAKEDSEN TVFDDSVAVL KELIKDPQQF EEDDEQGGVA MANDAIVNLI
ISAGVHISLL ELLRDNAVRE SIRKTQASVD SEADEKSEES HEYVVTRALE LLDLLARSRR
IRLLILEAGT ALDALVTAYE GTTDDYAESS PARQLIAQDL GRILIHLSSD PLEFRKTLYD
HRGVLPSAIL GNILSPVAEV AETAEEIVLN LVESDFATCP LWVDLIESAN VRLVFRVVVV
AKRPSVKVTA ARKLIDIVFS HPNILDDEED GLSPEEKSTL VSMLIDFFVD FDPRTSVVGV
LALTLLLKNG QTLNEEQMEK IAVDGAVSLV YWMQKGTERH QENAVKILHD GVKDPAILQK
FYEQLQAPSV QRETAFLLEL GQQLLDVEIK SNPEGLFKRC KLLQGLLEVT DYDSLPSDCM
EIVEEVSAYL LELTEEKGNE TEHKDEDADE KKTREKFLLV ITNFLAVLVS SSTFHSTLVH
QDAIEKLAFV LNEQKKATES SALVVDQTRR LLKQLCVHEV PRLVACNGVE ILLETVMKHD
EDSEEGSERV AEMLETFNSV VECGSAGKSA LMDTEGFLSS LSRGFKTVCG DLSEDQEVLT
AKLLGTDFDG RSTNMEVACG LCLLVFLLAR GGAYRERVFK DTELMQHIVT MMAWFPSIFS
TSDKVVTPEL KAKFGLIFAS GLPFLEAALV SAEGSMLDSD DKELFFRKTM SVYTKTLTTF
ANGHESSDLF LASCEGLKSL FHSDSAVSVL ADDGQKELEI LLKEQVFRSL KATIYSMGCV
VALLDIAVAV IPARPVTPDE EKEPARSSWL VAGVLHALFN FEAFGDDLDV SVLFTLLRRF
CSSAMIRNSL YEHVDYDRLV EILVAFAQDS KWRRWRKYAL SVLLLLGEDG ALEQVSHDRG
TMPMLQASTT SSFRDRDSEQ STCATRCFHC RQVVHAPVQV NLCVMPCPYC QKSIAVASDN
ASTAVDTLPS VVEHNGSITL DNGAQSKISS DGSDFVCVNC SNVLELPDGL GPSEIVCPHC
LQLASVKKTS QSVMPAFSSE KKRSSASSVR SVESGASLPK DPSMSGIDVR DTKVVSCGHC
GKHLIVKNGA SAVKCPSCHG VSKLSTTTTQ EMMRCKNCNT LLSLPAGARA YKCMKCLQTT
RLS
//
