ID V9H487_9CLOT Unreviewed; 692 AA.
AC V9H487;
DT 19-FEB-2014, integrated into UniProtKB/TrEMBL.
DT 19-FEB-2014, sequence version 1.
DT 24-JAN-2024, entry version 31.
DE RecName: Full=Flagellar hook-associated protein 2 {ECO:0000256|RuleBase:RU362066};
DE Short=HAP2 {ECO:0000256|RuleBase:RU362066};
DE AltName: Full=Flagellar cap protein {ECO:0000256|RuleBase:RU362066};
GN ORFNames=CSBG_02005 {ECO:0000313|EMBL:EEH98379.1};
OS Clostridium sp. 7_2_43FAA.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Clostridium.
OX NCBI_TaxID=457396 {ECO:0000313|EMBL:EEH98379.1, ECO:0000313|Proteomes:UP000017809};
RN [1] {ECO:0000313|EMBL:EEH98379.1, ECO:0000313|Proteomes:UP000017809}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=7_2_43FAA {ECO:0000313|EMBL:EEH98379.1,
RC ECO:0000313|Proteomes:UP000017809};
RG The Broad Institute Genome Sequencing Platform;
RA Earl A., Ward D., Feldgarden M., Gevers D., Allen-Vercoe E., Strauss J.,
RA Ambrose C., Young S.K., Zeng Q., Gargeya S., Fitzgerald M., Haas B.,
RA Abouelleil A., Alvarado L., Arachchi H.M., Berlin A., Chapman S.B.,
RA Gearin G., Goldberg J., Griggs A., Gujja S., Hansen M., Heiman D.,
RA Howarth C., Larimer J., Lui A., MacDonald P.J.P., McCowen C.,
RA Montmayeur A., Murphy C., Neiman D., Pearson M., Priest M., Roberts A.,
RA Saif S., Shea T., Sisk P., Stolte C., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Clostridium sp. 7_2_43FAA.";
RL Submitted (JAN-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Required for morphogenesis and for the elongation of the
CC flagellar filament by facilitating polymerization of the flagellin
CC monomers at the tip of growing filament. Forms a capping structure,
CC which prevents flagellin subunits (transported through the central
CC channel of the flagellum) from leaking out without polymerization at
CC the distal end. {ECO:0000256|RuleBase:RU362066}.
CC -!- SUBUNIT: Homopentamer. {ECO:0000256|ARBA:ARBA00011255,
CC ECO:0000256|RuleBase:RU362066}.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|RuleBase:RU362066}.
CC Bacterial flagellum {ECO:0000256|RuleBase:RU362066}.
CC -!- SIMILARITY: Belongs to the FliD family. {ECO:0000256|ARBA:ARBA00009764,
CC ECO:0000256|RuleBase:RU362066}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EEH98379.1}.
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DR EMBL; ACDK02000016; EEH98379.1; -; Genomic_DNA.
DR RefSeq; WP_008678036.1; NZ_JH815222.1.
DR AlphaFoldDB; V9H487; -.
DR STRING; 457396.CSBG_02005; -.
DR GeneID; 65398642; -.
DR eggNOG; COG1345; Bacteria.
DR HOGENOM; CLU_015182_0_1_9; -.
DR OrthoDB; 9776025at2; -.
DR Proteomes; UP000017809; Unassembled WGS sequence.
DR GO; GO:0009421; C:bacterial-type flagellum filament cap; IEA:InterPro.
DR GO; GO:0009424; C:bacterial-type flagellum hook; IEA:UniProtKB-UniRule.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0007155; P:cell adhesion; IEA:InterPro.
DR InterPro; IPR040026; FliD.
DR InterPro; IPR010809; FliD_C.
DR InterPro; IPR003481; FliD_N.
DR PANTHER; PTHR30288; FLAGELLAR CAP/ASSEMBLY PROTEIN FLID; 1.
DR PANTHER; PTHR30288:SF0; FLAGELLAR HOOK-ASSOCIATED PROTEIN 2; 1.
DR Pfam; PF07195; FliD_C; 1.
DR Pfam; PF02465; FliD_N; 1.
PE 3: Inferred from homology;
KW Bacterial flagellum {ECO:0000256|ARBA:ARBA00023143,
KW ECO:0000256|RuleBase:RU362066};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|RuleBase:RU362066};
KW Reference proteome {ECO:0000313|Proteomes:UP000017809};
KW Secreted {ECO:0000256|RuleBase:RU362066}.
FT DOMAIN 8..102
FT /note="Flagellar hook-associated protein 2 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02465"
FT DOMAIN 401..680
FT /note="Flagellar hook-associated protein 2 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF07195"
FT COILED 636..663
FT /evidence="ECO:0000256|RuleBase:RU362066"
SQ SEQUENCE 692 AA; 76830 MW; D4271DBDD0FCBF08 CRC64;
MRITGLATGL DMDQIVKDSM KPYRIKIDRK GQDKEILEIK QKLYREVIKD SREFYNKYFD
VTKSDSILLS KNWATTKFTS SNENVVTVTG GSDAKPGSYT ITGTTAKAAK IVLSTGINKD
DKISINGKEF ILKGDTEKDR ALNLNKELKE AGINVSVRYS DFAGSESGNA KGFIFESTVL
GKNGGFTIGG TEKVVENKVS GTDATYATIK GFTTKNFKIS YTNTISLQTE NGKVDIKISG
KDIQKDDGSG VDSEKLKKVL DTELLDYNLS VDISESGEVI FKSTVLGEVN DPQVVVNDNS
GSFDPGVNGK PATNSVNLEE VKGKKIFING NYIDLSSFTD ISSDEKKNEL LGHINKVISE
KNIDINAELN GNELVLKAKK NSSKYEINLS IVDGSSDITE GRDADITFKD SKSGVYKHTG
TSNTVTLDGI TFKFNGEIPE NTSITVNGKQ DVTDIKDNLV KFINDYNTLI EKLNKLTTEK
RNRDFDPLTA EQKKEMSEDE MKLWNEKVEK GQLSRDNDLT RISNSLKQAM RSLVDGSGLN
LEKIGISPVA DYQGVKNGTF TIDETKLTKA LEESSEEVMN LFIKSKPKED SLSEYTKYSK
SGIMQRLKDV LYNETVTVVA SLLKKAGIEG SSTSYNNELT KSIEKYEQKM LDMEKDFARR
EQALYTKYAN LETIMNKYNS QQSYLMQQLG LS
//
