ID V9HDS3_9CLOT Unreviewed; 285 AA.
AC V9HDS3;
DT 19-FEB-2014, integrated into UniProtKB/TrEMBL.
DT 19-FEB-2014, sequence version 1.
DT 27-MAR-2024, entry version 47.
DE RecName: Full=Cell division protein ZapA {ECO:0000256|ARBA:ARBA00015195};
DE AltName: Full=Z ring-associated protein ZapA {ECO:0000256|ARBA:ARBA00033158};
GN ORFNames=CSBG_01245 {ECO:0000313|EMBL:EEH97619.1};
OS Clostridium sp. 7_2_43FAA.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Clostridium.
OX NCBI_TaxID=457396 {ECO:0000313|EMBL:EEH97619.1, ECO:0000313|Proteomes:UP000017809};
RN [1] {ECO:0000313|EMBL:EEH97619.1, ECO:0000313|Proteomes:UP000017809}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=7_2_43FAA {ECO:0000313|EMBL:EEH97619.1,
RC ECO:0000313|Proteomes:UP000017809};
RG The Broad Institute Genome Sequencing Platform;
RA Earl A., Ward D., Feldgarden M., Gevers D., Allen-Vercoe E., Strauss J.,
RA Ambrose C., Young S.K., Zeng Q., Gargeya S., Fitzgerald M., Haas B.,
RA Abouelleil A., Alvarado L., Arachchi H.M., Berlin A., Chapman S.B.,
RA Gearin G., Goldberg J., Griggs A., Gujja S., Hansen M., Heiman D.,
RA Howarth C., Larimer J., Lui A., MacDonald P.J.P., McCowen C.,
RA Montmayeur A., Murphy C., Neiman D., Pearson M., Priest M., Roberts A.,
RA Saif S., Shea T., Sisk P., Stolte C., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Clostridium sp. 7_2_43FAA.";
RL Submitted (JAN-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Activator of cell division through the inhibition of FtsZ
CC GTPase activity, therefore promoting FtsZ assembly into bundles of
CC protofilaments necessary for the formation of the division Z ring. It
CC is recruited early at mid-cell but it is not essential for cell
CC division. {ECO:0000256|ARBA:ARBA00024910}.
CC -!- SUBUNIT: Homodimer. Interacts with FtsZ.
CC {ECO:0000256|ARBA:ARBA00026068}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EEH97619.1}.
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DR EMBL; ACDK02000032; EEH97619.1; -; Genomic_DNA.
DR RefSeq; WP_008679220.1; NZ_JH815222.1.
DR AlphaFoldDB; V9HDS3; -.
DR STRING; 457396.CSBG_01245; -.
DR GeneID; 65399398; -.
DR eggNOG; COG3027; Bacteria.
DR HOGENOM; CLU_825642_0_0_9; -.
DR OrthoDB; 1711036at2; -.
DR Proteomes; UP000017809; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0000917; P:division septum assembly; IEA:UniProtKB-KW.
DR Gene3D; 6.10.250.790; -; 1.
DR InterPro; IPR007838; Cell_div_ZapA-like.
DR InterPro; IPR036192; Cell_div_ZapA-like_sf.
DR PANTHER; PTHR34981; CELL DIVISION PROTEIN ZAPA; 1.
DR PANTHER; PTHR34981:SF1; CELL DIVISION PROTEIN ZAPA; 1.
DR Pfam; PF05164; ZapA; 1.
DR SUPFAM; SSF102829; Cell division protein ZapA-like; 1.
PE 4: Predicted;
KW Cell cycle {ECO:0000256|ARBA:ARBA00023306};
KW Cell division {ECO:0000256|ARBA:ARBA00022618};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Reference proteome {ECO:0000313|Proteomes:UP000017809};
KW Septation {ECO:0000256|ARBA:ARBA00023210}.
FT COILED 76..242
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 285 AA; 33371 MW; 230F630AC03C835B CRC64;
MNTVTIKING IEYNLKGREN EEYLLEVAKY VDGKVKDIMA NNRKLSSTAA ATLVALNIAD
ELFKADIEIE VLMKKNTSLD ERNLTLKERI KEIREEAEGI EFNTSREINK LNEIIDELNK
KLLEAEELKN KVTLLENENE ENNILREKIS KLEKEISAKE VDINEKDSLK LEIDSLKDEN
LTLREEVENC YKEVENLKET NELLKTNEVG YKEKFIKLNE ECKIMEDDFK KTKAEKDLLK
QRNKEIKFQL QNSKYKVLDL EKKLIDIQVK LAYEKKQKNA LLKDV
//
