ID   V9HHK9_9CLOT            Unreviewed;       556 AA.
AC   V9HHK9;
DT   19-FEB-2014, integrated into UniProtKB/TrEMBL.
DT   19-FEB-2014, sequence version 1.
DT   24-JAN-2024, entry version 46.
DE   SubName: Full=Putative alkyl hydroperoxide reductase F subunit {ECO:0000313|EMBL:EEH99001.1};
GN   ORFNames=CSBG_02627 {ECO:0000313|EMBL:EEH99001.1};
OS   Clostridium sp. 7_2_43FAA.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC   Clostridium.
OX   NCBI_TaxID=457396 {ECO:0000313|EMBL:EEH99001.1, ECO:0000313|Proteomes:UP000017809};
RN   [1] {ECO:0000313|EMBL:EEH99001.1, ECO:0000313|Proteomes:UP000017809}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=7_2_43FAA {ECO:0000313|EMBL:EEH99001.1,
RC   ECO:0000313|Proteomes:UP000017809};
RG   The Broad Institute Genome Sequencing Platform;
RA   Earl A., Ward D., Feldgarden M., Gevers D., Allen-Vercoe E., Strauss J.,
RA   Ambrose C., Young S.K., Zeng Q., Gargeya S., Fitzgerald M., Haas B.,
RA   Abouelleil A., Alvarado L., Arachchi H.M., Berlin A., Chapman S.B.,
RA   Gearin G., Goldberg J., Griggs A., Gujja S., Hansen M., Heiman D.,
RA   Howarth C., Larimer J., Lui A., MacDonald P.J.P., McCowen C.,
RA   Montmayeur A., Murphy C., Neiman D., Pearson M., Priest M., Roberts A.,
RA   Saif S., Shea T., Sisk P., Stolte C., Sykes S., Wortman J., Nusbaum C.,
RA   Birren B.;
RT   "The Genome Sequence of Clostridium sp. 7_2_43FAA.";
RL   Submitted (JAN-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EEH99001.1}.
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DR   EMBL; ACDK02000009; EEH99001.1; -; Genomic_DNA.
DR   RefSeq; WP_008676991.1; NZ_JH815222.1.
DR   AlphaFoldDB; V9HHK9; -.
DR   STRING; 457396.CSBG_02627; -.
DR   GeneID; 65398007; -.
DR   eggNOG; COG0492; Bacteria.
DR   eggNOG; COG3634; Bacteria.
DR   HOGENOM; CLU_031864_5_4_9; -.
DR   OrthoDB; 9806179at2; -.
DR   Proteomes; UP000017809; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR   GO; GO:0004791; F:thioredoxin-disulfide reductase (NADP) activity; IEA:InterPro.
DR   GO; GO:0019430; P:removal of superoxide radicals; IEA:InterPro.
DR   CDD; cd02974; AhpF_NTD_N; 1.
DR   Gene3D; 3.40.30.80; -; 1.
DR   Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 2.
DR   InterPro; IPR017561; AhpF_homologue_put.
DR   InterPro; IPR044142; AhpF_NTD_N.
DR   InterPro; IPR036188; FAD/NAD-bd_sf.
DR   InterPro; IPR023753; FAD/NAD-binding_dom.
DR   InterPro; IPR005982; Thioredox_Rdtase.
DR   InterPro; IPR012336; Thioredoxin-like_fold.
DR   InterPro; IPR036249; Thioredoxin-like_sf.
DR   NCBIfam; TIGR03143; AhpF_homolog; 1.
DR   NCBIfam; TIGR01292; TRX_reduct; 1.
DR   PANTHER; PTHR48105:SF16; THIOREDOXIN REDUCTASE 1-RELATED; 1.
DR   PANTHER; PTHR48105; THIOREDOXIN REDUCTASE 1-RELATED-RELATED; 1.
DR   Pfam; PF07992; Pyr_redox_2; 1.
DR   Pfam; PF13192; Thioredoxin_3; 1.
DR   PRINTS; PR00368; FADPNR.
DR   PRINTS; PR00469; PNDRDTASEII.
DR   SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR   SUPFAM; SSF52833; Thioredoxin-like; 2.
PE   4: Predicted;
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW   Reference proteome {ECO:0000313|Proteomes:UP000017809}.
FT   DOMAIN          5..297
FT                   /note="FAD/NAD(P)-binding"
FT                   /evidence="ECO:0000259|Pfam:PF07992"
FT   DOMAIN          480..555
FT                   /note="Thioredoxin-like fold"
FT                   /evidence="ECO:0000259|Pfam:PF13192"
SQ   SEQUENCE   556 AA;  60923 MW;  DDB655EFE1B0849D CRC64;
     MNKIYDLIII GGGPAGLSAG LYAGRARLNT LIIEKEHTGG QINSTAEIVN YPGIVKTTGP
     NLTSDMRTQA ENFGVKFQTA DVIDVDLSGD VKIIKTNNGE IQGRAIIIAT GASPRKLGFP
     GEIEYGGRGV AYCATCDGEF FKDLEVLVIG AGYAAAEEAI YLTRFAKKVI IVAREPEFTC
     AKSIGDKVKA NKNIEIRFNT EVVEAIGDDV LRSVKLINNV TNERSEYFPP KEDGTFGIFV
     FVGYEPQTKV FKDKIEMDRY GYILTNENME TNIKGVYAAG DLRPKLLRQV VTAVADGAIA
     ATDAERYVAS EKERLGIIEE EVIEEKVENK NEVPTSNNKA LSGRSNLLND TLRNQLKGIL
     SKIENNISLV SIVDESNKKS IELRDLVLDI SDLSDKISAV IYKKGENLEM ESKIHADKYP
     VVALLNKDSN YSGVKFHGVP GGHELNSFIL AIYNLAGPGQ ALNEDLLNEI KSLSLDKKTN
     IKVAVSLSCH VCPEVVTAAQ RIAIENPNIE TEMLDLSNFK DIKDKHKIMS VPALIINDSK
     VYFGGKKLED IVQLLK
//