ID V9K7F5_CALMI Unreviewed; 2491 AA.
AC V9K7F5;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Cubilin {ECO:0000313|EMBL:AFO93659.1};
DE Flags: Fragment;
OS Callorhinchus milii (Ghost shark).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Chondrichthyes;
OC Holocephali; Chimaeriformes; Callorhinchidae; Callorhinchus.
OX NCBI_TaxID=7868 {ECO:0000313|EMBL:AFO93659.1};
RN [1] {ECO:0000313|EMBL:AFO93659.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Intestine {ECO:0000313|EMBL:AFO93659.1};
RX PubMed=24402279; DOI=10.1038/nature12826;
RG International Elephant Shark Genome Sequencing Consortium;
RA Venkatesh B., Lee A.P., Ravi V., Maurya A.K., Lian M.M., Swann J.B.,
RA Ohta Y., Flajnik M.F., Sutoh Y., Kasahara M., Hoon S., Gangu V., Roy S.W.,
RA Irimia M., Korzh V., Kondrychyn I., Lim Z.W., Tay B.H., Tohari S.,
RA Kong K.W., Ho S., Lorente-Galdos B., Quilez J., Marques-Bonet T.,
RA Raney B.J., Ingham P.W., Tay A., Hillier L.W., Minx P., Boehm T.,
RA Wilson R.K., Brenner S., Warren W.C.;
RT "Elephant shark genome provides unique insights into gnathostome
RT evolution.";
RL Nature 505:174-179(2014).
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00059}.
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DR EMBL; JW861142; AFO93659.1; -; mRNA.
DR CDD; cd00041; CUB; 21.
DR Gene3D; 2.60.120.290; Spermadhesin, CUB domain; 21.
DR InterPro; IPR000859; CUB_dom.
DR InterPro; IPR035914; Sperma_CUB_dom_sf.
DR PANTHER; PTHR24251; OVOCHYMASE-RELATED; 1.
DR Pfam; PF00431; CUB; 21.
DR SMART; SM00042; CUB; 21.
DR SUPFAM; SSF49854; Spermadhesin, CUB domain; 21.
DR PROSITE; PS01180; CUB; 21.
PE 2: Evidence at transcript level;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00059}.
FT DOMAIN 31..143
FT /note="CUB"
FT /evidence="ECO:0000259|PROSITE:PS01180"
FT DOMAIN 144..260
FT /note="CUB"
FT /evidence="ECO:0000259|PROSITE:PS01180"
FT DOMAIN 262..377
FT /note="CUB"
FT /evidence="ECO:0000259|PROSITE:PS01180"
FT DOMAIN 381..493
FT /note="CUB"
FT /evidence="ECO:0000259|PROSITE:PS01180"
FT DOMAIN 494..610
FT /note="CUB"
FT /evidence="ECO:0000259|PROSITE:PS01180"
FT DOMAIN 614..726
FT /note="CUB"
FT /evidence="ECO:0000259|PROSITE:PS01180"
FT DOMAIN 727..839
FT /note="CUB"
FT /evidence="ECO:0000259|PROSITE:PS01180"
FT DOMAIN 856..970
FT /note="CUB"
FT /evidence="ECO:0000259|PROSITE:PS01180"
FT DOMAIN 971..1092
FT /note="CUB"
FT /evidence="ECO:0000259|PROSITE:PS01180"
FT DOMAIN 1096..1213
FT /note="CUB"
FT /evidence="ECO:0000259|PROSITE:PS01180"
FT DOMAIN 1215..1327
FT /note="CUB"
FT /evidence="ECO:0000259|PROSITE:PS01180"
FT DOMAIN 1331..1444
FT /note="CUB"
FT /evidence="ECO:0000259|PROSITE:PS01180"
FT DOMAIN 1449..1566
FT /note="CUB"
FT /evidence="ECO:0000259|PROSITE:PS01180"
FT DOMAIN 1568..1680
FT /note="CUB"
FT /evidence="ECO:0000259|PROSITE:PS01180"
FT DOMAIN 1684..1798
FT /note="CUB"
FT /evidence="ECO:0000259|PROSITE:PS01180"
FT DOMAIN 1799..1913
FT /note="CUB"
FT /evidence="ECO:0000259|PROSITE:PS01180"
FT DOMAIN 1915..2025
FT /note="CUB"
FT /evidence="ECO:0000259|PROSITE:PS01180"
FT DOMAIN 2032..2144
FT /note="CUB"
FT /evidence="ECO:0000259|PROSITE:PS01180"
FT DOMAIN 2148..2264
FT /note="CUB"
FT /evidence="ECO:0000259|PROSITE:PS01180"
FT DOMAIN 2266..2378
FT /note="CUB"
FT /evidence="ECO:0000259|PROSITE:PS01180"
FT DOMAIN 2382..2491
FT /note="CUB"
FT /evidence="ECO:0000259|PROSITE:PS01180"
FT DISULFID 1215..1242
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00059"
FT DISULFID 1915..1942
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00059"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:AFO93659.1"
SQ SEQUENCE 2491 AA; 274110 MW; 831EDF9C5B488091 CRC64;
HSNRLWIKFS SNSFFEKRGF MAHWDGTSTG CGGTLTTSTG SFTSPNYPMP YPHNTECYWR
IQINAGSIIE LDFDAFHLDS ISGCSYDYLA VYDGNSTNSY LLATLCGNQK PTTIRSTSNN
MYIKLRTDNS IGRGGFFAKY KSNCQNVIIA NHSRGVLESI NFPEDYPPEH NCNWTIQATE
GNTIDYSFNA FDLDSTYPSC YFTWVKLYDG PNDKSPLIGT FCDQTIPPAG TSNSSSLHVV
FCTELSYSSA AGFQMLWLQN GCGGDLFGPN GAVSSPGFPN WYPHNRECLW FLHVDEGNSI
EFTIHEFDVE YHKTCNFDVL EVYAGPDTRS PRLAQLCNTR LPNNPLVISS TGNAITVRFK
SNSKGNGKGF NATWKEKPGG CGGNFVAPKG EIHSPNFPNP YGNNVDCSWV ITVDTHYRVF
LNFTDFDTEN RQSCDSAYIA VHDGSNQGDP LLEKICDGKI PGGFTSTSNV MYVHFLSESN
VKNKGFRAQF NQVCGTLIVT DNIGGVITSP LYPNNYPDNQ NCSWIIQAQE PFKHVTLSFT
DFAIESNGKN CSTDALQILD GDNYEAPPIG RYCGATILQP ITSESNALVV NFVSNSGKSD
KGFRTTYAAS NSACGGSYHS ETGAFNSPNY PESYPSNYEC VWNLIGSPGN RVQLSFISFQ
IADSSSCASD YVEIREGNAT GQIYGKFCGT SLPKNYTSVT GHILWVKFVS DSSQNDAGFK
ATFSHLYGNE IMGTQGQITS PLWPHHYPNN ARYHWTITAP EGNIIHVKIL VMDIDDLSVC
ARNRLRFYDG PDVNSRLIVT YCGYEPPPPV VSFGTTLTIE FSSDDSSNGQ GFLLEWHAQQ
YTINPTAIPT IPPGACGGNV MTGESPAFLY SPGWPNEYQI HLNCMWVIWS PRSTVELNIM
ALDIESADSK CSLDSLVIRD GDDSLSPVLA TLCGKELPGP IRSTGEAMFI QFIADTANSG
GGFNASYHKM CGGLLHADRG VITSPNYPQP YTANLNCTWH VLATSGSIIS LHFEKLFQVQ
ASGSSCSNGD YLEFRNGYDS SSPPLTSSGG NGRYCGEVPP STMRTTDNRL SVRFISDGSS
EGQGFKFTYE ASYMACGATI YVSNFDPVGN ISSMNYPNNY PQNIDCTWTI TVPAGEAVQL
DFEDLFYIEP DSQCAFDYLE LHDGPSSNSP LISRLCGSTS PSTQKSTGNV MHVRFRTDAR
TTHAGFKARY SIARCGGTLI GIDGYLQSPG YPSSNYPDNV QCEWYLKGPT GHYLTITYDA
LDLEDTPNCT KDFVEIREYS STGRLLGKHC GSTTFDPMDT SDSFAYVRFH TDASNNKKGF
RLGFEASVDG CGGELTASTG TITSPNYPNL YPHSRRCVWK ITVQEGRRVT LTITDLHLEA
HENCDLDFVA IYNGLQPNSP RLQKYCGNLN SNVSVMSSGN TMQLVFVTDA LVSNGGFSAT
YTSEEDAVCG GTLGDPNEGT FTSPGYNGKL DYMSNLNCEW LIQNPSSTGS SIYIEFINFH
LEHHTLCEQD HVAIRSENSA GELLVQLCGE LTPGLSLVIA NSQVWVHFMS NPSVEDIGFN
AKYRFTECGG IQTGSTGRIS SPNFPSPYTA STHCAWLLEA PEGHTISLSF TVFELEPHSA
CTVDSVTIKN GGSSSSPIIG QYCGTNSPGT IKSGSNRLLV IFNSNNTVPH KGFDATWTSD
SAGCGGILHA DDGSFDSPNW PVDFPKNSEC TWKIVAHRSK HLELSFDDNF LIPDNSGHCE
DSYVKVWAGD AEQDGTLLTT ACGDVPPSLV TIPANVMTAR FRSADSVGKG FSASFTSRCG
ANFTDLSGLV MSPNYPHNYD INMNCEYFID ASKDMFVILQ FEAFALEDGF KCEHDALKIY
SETTATSDET QLLITLCGSV LPATISVHGP MLLTFQTNNM TTDMGFLAKY HLVPCGGTFQ
ESSGIVTSPA YSYTNYNHKI NCTYHIIVRE NRLVELKFSD FDLELLCSDY VSVHDGSNIF
APSLGKFCGS TIPPPLLSSS NSMFIVFTTD IIVSGRGWKA LYVETLGPNQ GCGGYLNSTS
GTFGSPDMEF DGKYEKNLNC LWNISAPDNH FINITFTAFQ LEAETDGVCH DYLSIYDESS
KLIGTYCGSQ LPFSVVSTYN LLAVKFFSNA FIELAGFNVT YKTHEYPCGG KFKANSTSQI
LTSPEYPNNY PPLTICHWII DAPENEQVGV VIQELDLPAT PNCSLEYLEI KDSHILGDNG
QNIRLCGSNL IIPAFYSYGH RFRINFYSKV YQNGNKLHLT YQSTNCSREY NQSFGYLKSP
GWPAEYPNNL NCKIILRAPK NHKISLFFNA FYLELQKDCK LDYLEVHNGT PGHEQAIGKF
CGYHLPNPIF SHTHELTLIF KSDAISTYAG FEITWTSSPN ECGGTLYGPS GSFYSPNYPE
DHYDNTDCEW IIQAPVGRVI TFNFPVLSID GECKKTYLNF YDGVDSSSKL IKSYCETDTI
ATFTSSSSNV FVKFHAEDAF PSSKFRILWT S
//
