ID V9K8M3_CALMI Unreviewed; 1465 AA.
AC V9K8M3;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 27-MAR-2024, entry version 43.
DE SubName: Full=ATPase family AAA domain-containing protein 2B {ECO:0000313|EMBL:AFO93954.1};
OS Callorhinchus milii (Ghost shark).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Chondrichthyes;
OC Holocephali; Chimaeriformes; Callorhinchidae; Callorhinchus.
OX NCBI_TaxID=7868 {ECO:0000313|EMBL:AFO93954.1};
RN [1] {ECO:0000313|EMBL:AFO93954.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Ovary {ECO:0000313|EMBL:AFO93954.1};
RX PubMed=24402279; DOI=10.1038/nature12826;
RG International Elephant Shark Genome Sequencing Consortium;
RA Venkatesh B., Lee A.P., Ravi V., Maurya A.K., Lian M.M., Swann J.B.,
RA Ohta Y., Flajnik M.F., Sutoh Y., Kasahara M., Hoon S., Gangu V., Roy S.W.,
RA Irimia M., Korzh V., Kondrychyn I., Lim Z.W., Tay B.H., Tohari S.,
RA Kong K.W., Ho S., Lorente-Galdos B., Quilez J., Marques-Bonet T.,
RA Raney B.J., Ingham P.W., Tay A., Hillier L.W., Minx P., Boehm T.,
RA Wilson R.K., Brenner S., Warren W.C.;
RT "Elephant shark genome provides unique insights into gnathostome
RT evolution.";
RL Nature 505:174-179(2014).
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DR EMBL; JW861437; AFO93954.1; -; mRNA.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR CDD; cd05528; Bromo_AAA; 1.
DR CDD; cd19517; RecA-like_Yta7-like; 1.
DR Gene3D; 1.10.8.60; -; 1.
DR Gene3D; 1.20.920.10; Bromodomain-like; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR041569; AAA_lid_3.
DR InterPro; IPR045199; ATAD2-like.
DR InterPro; IPR003959; ATPase_AAA_core.
DR InterPro; IPR003960; ATPase_AAA_CS.
DR InterPro; IPR001487; Bromodomain.
DR InterPro; IPR036427; Bromodomain-like_sf.
DR InterPro; IPR018359; Bromodomain_CS.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR23069; AAA DOMAIN-CONTAINING; 1.
DR PANTHER; PTHR23069:SF5; ATPASE FAMILY AAA DOMAIN-CONTAINING PROTEIN 2B; 1.
DR Pfam; PF00004; AAA; 2.
DR Pfam; PF17862; AAA_lid_3; 1.
DR Pfam; PF00439; Bromodomain; 1.
DR PRINTS; PR00503; BROMODOMAIN.
DR SMART; SM00382; AAA; 1.
DR SMART; SM00297; BROMO; 1.
DR SUPFAM; SSF47370; Bromodomain; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS00674; AAA; 1.
DR PROSITE; PS00633; BROMODOMAIN_1; 1.
DR PROSITE; PS50014; BROMODOMAIN_2; 1.
PE 2: Evidence at transcript level;
KW Bromodomain {ECO:0000256|ARBA:ARBA00023117, ECO:0000256|PROSITE-
KW ProRule:PRU00035}.
FT DOMAIN 957..1020
FT /note="Bromo"
FT /evidence="ECO:0000259|PROSITE:PS50014"
FT REGION 1..132
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 217..338
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1064..1124
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1140..1181
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1245..1296
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 11..26
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 28..45
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 54..68
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 95..115
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 116..132
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 227..259
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 312..331
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1093..1107
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1110..1124
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1149..1167
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1252..1269
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1465 AA; 166231 MW; 881FBCBEFA01BE3A CRC64;
MVRTRRNSAV EAEPKTNSGR ISSRTRSTRS SVKHEEPKRD NGNDDASLSD SQIEPPAKRR
RRNADTVSSD LSADRSPHNS GPAEEWRGTP RPSRLSTRAG ASIQNGHSSL VLRTGNRREA
QEDGDHSLMN GDSEVRRSGR ARRNKFETLN QSLLFDQLVN STAEAVLQEM DNITSNIRQN
RRPGEVERLR MWADTEFENM DMYSRVKRKR KPLRRNMYGM PIHVEETSEG DEEEEEEEEG
SEESQEEEED VDEAEEAEEN DRPYNLRQRK AVQRYQAPPI EPVHRRQRQS TLFDTHRSPA
RRSHIRRKKH AIHSSDTTSS SDEERFERRK SKSMARARNR CLPMNIRAED LASGILRERV
KVGASLADVD PMNIDTSVWF DSVGGLSQHI QALKEMVVFP LLYPEVFERF KIQPPRGCLF
YGPPGTGKTL VARALANECG QGDKKVSFFM RKGADCLSKW VGESERQLRL LFDQAYLMRP
SIIFFDEIDG LAPVRSSRQD QIHSSIVSTL LALMDGLDNR GEIVIIGATN RLDSIDPALR
RPGRFDREFL FNLPDKKARK HIFQIHTRDW NPKLLQPFLE ELAEKCVGYC GADIKALCTE
AALFALRRRY PQIYESRQKL QLDVSSIVIN AQDFYLAMQN IVPASQRAVC SPGQALSHII
KPLLENVFNE ILIALYKIFP HAEQTTNENK DDGTSNVLED CIYSDDEDEA AIFDSISLGS
PKKQPPAPKR KPFLHFSMSA HHQPTSHRPR LLLCGDKGCG QSSQLAPALL HSLERFSVHR
LDLPALYSVS AKTPEESCAQ VFREARRTVP SIIYMPHIRE WWDAVSETVK ATFMTLLQDI
PSFSPILIMA TSETAYAELP DEIKCIFAVD YGEIIVLQRP GEDERTRFFE DLILNQAAKP
PPRKKKAAFV ALEVLQPAQP PTPKQLSEEE QKRMEEQEEN TLRELRLFLR DITKRLATDK
RFSIFSKPVD IEEVSDYLEV IKQPMDLSTI MTKIDNHQYE TVQHFLTDIS LICSNALEYN
PDKDPGDRII RHRACTLKDT SHAIVAAELD PEFNKLCEDI RESRRKQGIS PVDQQTNHSA
TAKREDSTQD SSHNLEARTT NGECKQTIQI KRKPRRRSKW GRGIIKKSKK VNHLKKDDFN
KSYEADGDLG EESELAENGE LEVSTDYPEE NGDLSLTNDE SSCDIMDVNQ MANKLENGTI
KKESAGVKST GKEDCADFLT DGNNEFPLTK EKAAPGEQCV PNDACSAGKE SAPTECTWSD
ESMASAESEP SQECLAGGEY TPNDDSIPGK DDLSDAKHER GKECEHTKAS MIQLVPNAKI
PVVEKDRKHL VEESSHSDTH PTQPDIVVKC SQNEDIALKA LELEKDVLGS VKQGQPAHAE
HQTVVHMEQV LEDILEPIPP LIVDHAQLKH FLQLAVKKSN NFTVDQLEKL YSLLSQCIYR
HRKEYDKSCL LEEMENLLKT FQTFL
//
