ID V9KHH5_CALMI Unreviewed; 756 AA.
AC V9KHH5;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 24-JAN-2024, entry version 28.
DE SubName: Full=PERQ amino acid-rich with GYF domain-containing protein 2-like protein {ECO:0000313|EMBL:AFO97440.1};
DE Flags: Fragment;
OS Callorhinchus milii (Ghost shark).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Chondrichthyes;
OC Holocephali; Chimaeriformes; Callorhinchidae; Callorhinchus.
OX NCBI_TaxID=7868 {ECO:0000313|EMBL:AFO97440.1};
RN [1] {ECO:0000313|EMBL:AFO97440.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Heart {ECO:0000313|EMBL:AFO97440.1};
RX PubMed=24402279; DOI=10.1038/nature12826;
RG International Elephant Shark Genome Sequencing Consortium;
RA Venkatesh B., Lee A.P., Ravi V., Maurya A.K., Lian M.M., Swann J.B.,
RA Ohta Y., Flajnik M.F., Sutoh Y., Kasahara M., Hoon S., Gangu V., Roy S.W.,
RA Irimia M., Korzh V., Kondrychyn I., Lim Z.W., Tay B.H., Tohari S.,
RA Kong K.W., Ho S., Lorente-Galdos B., Quilez J., Marques-Bonet T.,
RA Raney B.J., Ingham P.W., Tay A., Hillier L.W., Minx P., Boehm T.,
RA Wilson R.K., Brenner S., Warren W.C.;
RT "Elephant shark genome provides unique insights into gnathostome
RT evolution.";
RL Nature 505:174-179(2014).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the GIGYF family.
CC {ECO:0000256|ARBA:ARBA00038015}.
CC -!- SIMILARITY: Belongs to the TFIIA subunit 1 family.
CC {ECO:0000256|ARBA:ARBA00010059}.
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DR EMBL; JW864923; AFO97440.1; -; mRNA.
DR AlphaFoldDB; V9KHH5; -.
DR GO; GO:0005672; C:transcription factor TFIIA complex; IEA:InterPro.
DR GO; GO:0006367; P:transcription initiation at RNA polymerase II promoter; IEA:InterPro.
DR CDD; cd00072; GYF; 1.
DR CDD; cd07976; TFIIA_alpha_beta_like; 1.
DR Gene3D; 3.30.1490.40; -; 1.
DR Gene3D; 2.30.18.10; Transcription factor IIA (TFIIA), beta-barrel domain; 1.
DR InterPro; IPR003169; GYF.
DR InterPro; IPR035445; GYF-like_dom_sf.
DR InterPro; IPR004855; TFIIA_asu/bsu.
DR InterPro; IPR009088; TFIIA_b-brl.
DR PANTHER; PTHR14445; GRB10 INTERACTING GYF PROTEIN; 1.
DR PANTHER; PTHR14445:SF38; GRB10-INTERACTING GYF PROTEIN 2; 1.
DR Pfam; PF02213; GYF; 1.
DR Pfam; PF03153; TFIIA; 1.
DR SMART; SM00444; GYF; 1.
DR SMART; SM01371; TFIIA; 1.
DR SUPFAM; SSF55277; GYF domain; 1.
DR SUPFAM; SSF50784; Transcription factor IIA (TFIIA), beta-barrel domain; 1.
DR PROSITE; PS50829; GYF; 1.
PE 2: Evidence at transcript level;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Transcription {ECO:0000256|ARBA:ARBA00023163}.
FT DOMAIN 510..558
FT /note="GYF"
FT /evidence="ECO:0000259|PROSITE:PS50829"
FT REGION 64..162
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 190..238
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 262..448
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 637..708
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 100..136
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 138..159
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 190..217
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 262..281
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 311..362
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 385..408
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 410..426
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 433..448
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 657..681
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 688..708
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:AFO97440.1"
SQ SEQUENCE 756 AA; 85683 MW; 0059E5465D92DC1E CRC64;
REEMLALYVK DLKIPVDLSD KEFLPILQEE PLPPLALVPF TEEEQRNFSM SVNSLAVLRL
MGRGGGTVAG APRGRSSSRG RGRGRGEGGF YQRSFDEGEV GFGRGSREMH RSQSWEERGE
RRFEKPGRKD PGSSHVKDQH PSLCTQNDFL SSTSGFLTKP VRPTFEEVGT STTRKHEFIR
SESDNWRVCR DEQNGEEDDG GWRLAGPRRE GDRWRTHSPG PFDILTRPEN RYEADAPRSA
GWREVLERRR RFEFDFRDRD DERGYRRVPS GSGSLEDERD SLPEWCLEDA EEETGTFDSS
GAFMSLKIKK APKEPIPEEQ ELDFKPVEDG DERSNSENEK EAKEPDKTTK RESFEEPVRT
EEPKAVPSTA LPPPPSQSHI FVIPSTHNKE ERKPEKNNKI EATEKCRPAA SEEMNTSASS
PPQKKTPAVS AVPIATVSKS SPSPSSVTTV VTNVSIPQDN DDDGLKHLEQ EAEKMVASLQ
DNALDDERLS TKIQEKRTKS STLPLSHDAA MKWFYKDPQG EIQGPFSNQE MAEWFQAGYF
TMSLLVKRGC DEGFQPLGEV IKMWGRVPFA PGPSPPPLLG DLDQERLKRQ QELATLNLFQ
MQQIQYQQFL QAQLMTRQQY AQAIAHQQKA VVGSITSQQQ QQQQQPPLVM QVDGAGDTSS
EEDEDDEEDE YDDEEEEKDK EEVGEGGQVE EESLNSEDDV SDEEGQELFD TENVVVCQYD
KIHRSKNKWK FHLKDGIMNL NGRDFVFSKA IGDAEW
//
