ID V9KLL2_CALMI Unreviewed; 587 AA.
AC V9KLL2;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=Autophagy-related protein 16-1-like protein {ECO:0000313|EMBL:AFO98977.1};
OS Callorhinchus milii (Ghost shark).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Chondrichthyes;
OC Holocephali; Chimaeriformes; Callorhinchidae; Callorhinchus.
OX NCBI_TaxID=7868 {ECO:0000313|EMBL:AFO98977.1};
RN [1] {ECO:0000313|EMBL:AFO98977.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Liver {ECO:0000313|EMBL:AFO98977.1};
RX PubMed=24402279; DOI=10.1038/nature12826;
RG International Elephant Shark Genome Sequencing Consortium;
RA Venkatesh B., Lee A.P., Ravi V., Maurya A.K., Lian M.M., Swann J.B.,
RA Ohta Y., Flajnik M.F., Sutoh Y., Kasahara M., Hoon S., Gangu V., Roy S.W.,
RA Irimia M., Korzh V., Kondrychyn I., Lim Z.W., Tay B.H., Tohari S.,
RA Kong K.W., Ho S., Lorente-Galdos B., Quilez J., Marques-Bonet T.,
RA Raney B.J., Ingham P.W., Tay A., Hillier L.W., Minx P., Boehm T.,
RA Wilson R.K., Brenner S., Warren W.C.;
RT "Elephant shark genome provides unique insights into gnathostome
RT evolution.";
RL Nature 505:174-179(2014).
CC -!- SIMILARITY: Belongs to the WD repeat ATG16 family.
CC {ECO:0000256|ARBA:ARBA00009271}.
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DR EMBL; JW866460; AFO98977.1; -; mRNA.
DR AlphaFoldDB; V9KLL2; -.
DR GO; GO:0000045; P:autophagosome assembly; IEA:InterPro.
DR CDD; cd00200; WD40; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 3.
DR InterPro; IPR045160; ATG16.
DR InterPro; IPR013923; Autophagy-rel_prot_16_dom.
DR InterPro; IPR020472; G-protein_beta_WD-40_rep.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR019775; WD40_repeat_CS.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR19878; AUTOPHAGY PROTEIN 16-LIKE; 1.
DR PANTHER; PTHR19878:SF7; PROTEIN ATG16L2; 1.
DR Pfam; PF08614; ATG16; 1.
DR Pfam; PF00400; WD40; 6.
DR PRINTS; PR00320; GPROTEINBRPT.
DR SMART; SM00320; WD40; 7.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS00678; WD_REPEATS_1; 3.
DR PROSITE; PS50082; WD_REPEATS_2; 5.
DR PROSITE; PS50294; WD_REPEATS_REGION; 4.
PE 2: Evidence at transcript level;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW ProRule:PRU00221}.
FT DOMAIN 17..189
FT /note="Autophagy-related protein 16"
FT /evidence="ECO:0000259|Pfam:PF08614"
FT REPEAT 298..331
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 342..383
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 384..425
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 522..551
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 553..587
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT COILED 114..190
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 587 AA; 66719 MW; 4762E3785B2AA101 CRC64;
MASGGSGSVA AECKRNIARK LRIRDRHQSH RYSAVITRYN QLLERANVLR QWRDVCNPSS
VPSSPSDVSD LQVRHQEKVT AIHRQNGQLA EDFISLRKKL EEKEPELELT QGRMAKLEHQ
REWLDVERRK LSQRVLTLEQ VNRSVREEYE GLRGRCWDWD QQLRALEMEN AEIIRDLMEL
KARAARAQNH RIEEPQRVQQ CCLQKDLAVF SNTPVCIDTD EEKESHPPID VADELKMRTN
RDKLFRSASV SLPRSSNFLQ NIKQLFVRRR GSSSVSEVSD PIRICVSATV PTISKQCLEV
HDGEVNAVQF SPNSNLLATG GSDRTIKLWD MVRGTLQNPK ALVGSNDGIT SLEFDPLGSM
ILAGSYDNSA RLWSLDTYEL KHTLSGHSGK VTAAKFKSYL RQVVTGSYDG TLRIWDLHKE
ACVSSIAVNS RCSDVICSDY FIVSGHMDKK IRFWDCRTQT ISNEIHLQEK VTSLDMSGDR
TQLLSLSRDD LLRVMDMRMN NVRKELRAEG FKCGTDWTKA IFSPDGNYVV SGSIDGVLYI
WNVDTEKLET SLVGEHRATV NAISWSPSGD YVVSVDRAKR ATLWTDF
//
