ID   V9KR41_CALMI            Unreviewed;       471 AA.
AC   V9KR41;
DT   19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT   19-MAR-2014, sequence version 1.
DT   27-MAR-2024, entry version 26.
DE   SubName: Full=TRAF family member-associated NF-kappa-B activator-like protein {ECO:0000313|EMBL:AFP00825.1};
OS   Callorhinchus milii (Ghost shark).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Chondrichthyes;
OC   Holocephali; Chimaeriformes; Callorhinchidae; Callorhinchus.
OX   NCBI_TaxID=7868 {ECO:0000313|EMBL:AFP00825.1};
RN   [1] {ECO:0000313|EMBL:AFP00825.1}
RP   NUCLEOTIDE SEQUENCE.
RC   TISSUE=Gills {ECO:0000313|EMBL:AFP00825.1};
RX   PubMed=24402279; DOI=10.1038/nature12826;
RG   International Elephant Shark Genome Sequencing Consortium;
RA   Venkatesh B., Lee A.P., Ravi V., Maurya A.K., Lian M.M., Swann J.B.,
RA   Ohta Y., Flajnik M.F., Sutoh Y., Kasahara M., Hoon S., Gangu V., Roy S.W.,
RA   Irimia M., Korzh V., Kondrychyn I., Lim Z.W., Tay B.H., Tohari S.,
RA   Kong K.W., Ho S., Lorente-Galdos B., Quilez J., Marques-Bonet T.,
RA   Raney B.J., Ingham P.W., Tay A., Hillier L.W., Minx P., Boehm T.,
RA   Wilson R.K., Brenner S., Warren W.C.;
RT   "Elephant shark genome provides unique insights into gnathostome
RT   evolution.";
RL   Nature 505:174-179(2014).
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DR   EMBL; JW868307; AFP00825.1; -; mRNA.
DR   AlphaFoldDB; V9KR41; -.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0007249; P:canonical NF-kappaB signal transduction; IEA:InterPro.
DR   InterPro; IPR041641; CALCOCO1/2_Zn_UBZ1.
DR   InterPro; IPR039669; TANK.
DR   InterPro; IPR024581; TBD.
DR   PANTHER; PTHR15249; TRAF FAMILY MEMBER-ASSOCIATED NF-KAPPA-B ACTIVATOR; 1.
DR   PANTHER; PTHR15249:SF0; TRAF FAMILY MEMBER-ASSOCIATED NF-KAPPA-B ACTIVATOR; 1.
DR   Pfam; PF12845; TBD; 1.
DR   PROSITE; PS51905; ZF_UBZ1; 1.
PE   2: Evidence at transcript level;
KW   Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833};
KW   Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU01253}.
FT   DOMAIN          435..462
FT                   /note="UBZ1-type"
FT                   /evidence="ECO:0000259|PROSITE:PS51905"
FT   REGION          62..87
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          334..356
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          15..42
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          112..139
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        62..82
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   471 AA;  52985 MW;  0F1DC0BBE141C5CC CRC64;
     MNKNNLEDPY DACCLGCREK DIKTLEQRID DLQRELAVKS NVIINLQCAS TIPRGEALDT
     LAHGTKDDLP KPRRRDSQRP AAFHLSEDPT AVLTRERDCK LTAENSQLNE RINKFQDEQK
     QFKSIIEQQE QELRMLRKQL DVGLYRHDQQ QCHHPDVKVN RKMADPFSLK AGPSAKTDHL
     TNEEELEMFF QQICQQFKQL STLTTKQAEL LGKSKYSNNT IDLDFSIPIQ CTDEGAHEQA
     EGPCIGKEGK KVCKGPSTAQ GSGVYQNQLP VVQSLSELNI KFPPSDGDYE FLNSAAEKPQ
     TKPAFEGPGD TVEKAVLKDT VQDMACKKFN KPECTSLETS PEEPTTEAAQ NPFCDEQKPS
     TNFTVLTYVK DDNSPFRNPA GPAHKPFRNI EESHKVFQSS PTEIRGPQKT LWTPHHNKDG
     ILPQGAGNSD LESNSKICEF CHKVFPAGTK SKEDFLRHLN SHFKDGAKNG F
//