ID V9L831_CALMI Unreviewed; 283 AA.
AC V9L831;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 22-FEB-2023, entry version 35.
DE SubName: Full=Membrane frizzled-related protein-like protein {ECO:0000313|EMBL:AFP08353.1};
DE Flags: Fragment;
OS Callorhinchus milii (Ghost shark).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Chondrichthyes;
OC Holocephali; Chimaeriformes; Callorhinchidae; Callorhinchus.
OX NCBI_TaxID=7868 {ECO:0000313|EMBL:AFP08353.1};
RN [1] {ECO:0000313|EMBL:AFP08353.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Brain {ECO:0000313|EMBL:AFP08353.1};
RX PubMed=24402279; DOI=10.1038/nature12826;
RG International Elephant Shark Genome Sequencing Consortium;
RA Venkatesh B., Lee A.P., Ravi V., Maurya A.K., Lian M.M., Swann J.B.,
RA Ohta Y., Flajnik M.F., Sutoh Y., Kasahara M., Hoon S., Gangu V., Roy S.W.,
RA Irimia M., Korzh V., Kondrychyn I., Lim Z.W., Tay B.H., Tohari S.,
RA Kong K.W., Ho S., Lorente-Galdos B., Quilez J., Marques-Bonet T.,
RA Raney B.J., Ingham P.W., Tay A., Hillier L.W., Minx P., Boehm T.,
RA Wilson R.K., Brenner S., Warren W.C.;
RT "Elephant shark genome provides unique insights into gnathostome
RT evolution.";
RL Nature 505:174-179(2014).
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00090}.
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DR EMBL; JW875836; AFP08353.1; -; mRNA.
DR AlphaFoldDB; V9L831; -.
DR CDD; cd07066; CRD_FZ; 1.
DR CDD; cd00041; CUB; 1.
DR CDD; cd00112; LDLa; 1.
DR Gene3D; 1.10.2000.10; Frizzled cysteine-rich domain; 1.
DR Gene3D; 4.10.400.10; Low-density Lipoprotein Receptor; 1.
DR Gene3D; 2.60.120.290; Spermadhesin, CUB domain; 1.
DR InterPro; IPR000859; CUB_dom.
DR InterPro; IPR020067; Frizzled_dom.
DR InterPro; IPR036790; Frizzled_dom_sf.
DR InterPro; IPR036055; LDL_receptor-like_sf.
DR InterPro; IPR002172; LDrepeatLR_classA_rpt.
DR InterPro; IPR035914; Sperma_CUB_dom_sf.
DR PANTHER; PTHR24251:SF36; MEMBRANE FRIZZLED-RELATED PROTEIN; 1.
DR PANTHER; PTHR24251; OVOCHYMASE-RELATED; 1.
DR Pfam; PF00431; CUB; 1.
DR Pfam; PF01392; Fz; 1.
DR Pfam; PF00057; Ldl_recept_a; 1.
DR SMART; SM00042; CUB; 1.
DR SMART; SM00063; FRI; 1.
DR SMART; SM00192; LDLa; 1.
DR SUPFAM; SSF63501; Frizzled cysteine-rich domain; 1.
DR SUPFAM; SSF57424; LDL receptor-like module; 1.
DR SUPFAM; SSF49854; Spermadhesin, CUB domain; 1.
DR PROSITE; PS01180; CUB; 1.
DR PROSITE; PS50038; FZ; 1.
DR PROSITE; PS50068; LDLRA_2; 1.
PE 2: Evidence at transcript level;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00124}.
FT DOMAIN 7..117
FT /note="CUB"
FT /evidence="ECO:0000259|PROSITE:PS01180"
FT DOMAIN 165..283
FT /note="FZ"
FT /evidence="ECO:0000259|PROSITE:PS50038"
FT DISULFID 124..136
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 131..149
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 143..158
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:AFP08353.1"
SQ SEQUENCE 283 AA; 31742 MW; 2DDE55F9C29DFADE CRC64;
LREQPGCGGL LTAPEGSLSS PHYPELYPHG QRCVWWLSAP RGYRIRLLFL RFGFGDVCRF
DFLEVHDGPS VRDGHLMGRF CGVSLPPMLT SSRPHMTVVF VAEGQSDVGF EAEFHWTEPR
DERCGPEELR CGSGECRAQR WVCDGWSDCE DGSDEENCTG VTVPPYESDC EQIEVPMCQG
LRYNETSFPN LWLRIADQRS AVTLLKDYTV LTQLLCYENL RALTCSIVVP MCTRAGGLVP
PCQAACRAAE ERCQRPLAFL GILWPFNCHL FPDSQDPVVC VTP
//
