ID V9VVT9_9RHOB Unreviewed; 260 AA.
AC V9VVT9;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 24-JAN-2024, entry version 35.
DE SubName: Full=NG,NG-dimethylarginine dimethylaminohydrolase {ECO:0000313|EMBL:AHD01784.1};
GN ORFNames=METH_14770 {ECO:0000313|EMBL:AHD01784.1};
OS Leisingera methylohalidivorans DSM 14336.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC Roseobacteraceae; Leisingera.
OX NCBI_TaxID=999552 {ECO:0000313|EMBL:AHD01784.1, ECO:0000313|Proteomes:UP000018780};
RN [1] {ECO:0000313|EMBL:AHD01784.1, ECO:0000313|Proteomes:UP000018780}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 14336 {ECO:0000313|EMBL:AHD01784.1,
RC ECO:0000313|Proteomes:UP000018780};
RG DOE Joint Genome Institute;
RA Klenk H.-P., Huntemann M., Han J., Chen A., Kyrpides N., Mavromatis K.,
RA Markowitz V., Palaniappan K., Ivanova N., Schaumberg A., Pati A.,
RA Liolios K., Nordberg H.P., Cantor M.N., Hua S.X., Woyke T.;
RL Submitted (SEP-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the DDAH family.
CC {ECO:0000256|ARBA:ARBA00008532}.
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DR EMBL; CP006773; AHD01784.1; -; Genomic_DNA.
DR RefSeq; WP_024091156.1; NC_023135.1.
DR AlphaFoldDB; V9VVT9; -.
DR STRING; 999552.METH_14770; -.
DR KEGG; lmd:METH_14770; -.
DR PATRIC; fig|999552.6.peg.2957; -.
DR HOGENOM; CLU_067923_1_0_5; -.
DR OrthoDB; 9790596at2; -.
DR Proteomes; UP000018780; Chromosome.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR InterPro; IPR033199; DDAH-like.
DR PANTHER; PTHR12737:SF9; DIMETHYLARGININASE; 1.
DR PANTHER; PTHR12737; DIMETHYLARGININE DIMETHYLAMINOHYDROLASE; 1.
DR Pfam; PF02274; ADI; 1.
DR SUPFAM; SSF55909; Pentein; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:AHD01784.1}.
FT ACT_SITE 168
FT /note="Proton donor"
FT /evidence="ECO:0000256|PIRSR:PIRSR633199-1"
FT ACT_SITE 255
FT /note="Nucleophile"
FT /evidence="ECO:0000256|PIRSR:PIRSR633199-1"
FT BINDING 24
FT /ligand="substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR633199-2"
FT BINDING 66
FT /ligand="substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR633199-2"
FT BINDING 71..72
FT /ligand="substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR633199-2"
FT BINDING 91
FT /ligand="substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR633199-2"
FT BINDING 137
FT /ligand="substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR633199-2"
FT BINDING 249
FT /ligand="substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR633199-2"
SQ SEQUENCE 260 AA; 27741 MW; 6C3E5CBFC99E2647 CRC64;
MKNPSFEFSR AITRRPASTI ANGLRAEDIG NPDLDSMLAA HAAYVAALRS TGAEVIELEP
LDAFPDAQFV EDTALCLPQG AILMRPGAPS RLGEVAEMAP TLRGCYENVR EIKSPGHIEG
GDILVTGSEI LVGRSDRTDA AGVAELAAIA AEWGHSLREV FTPEGVLHFK TDCSLMDAET
ILSTKRLDAS GCFEGYRVLH VAEGEEAAAN AIRFNNLVLM AAGFPRTAEV LSKAGYEIVE
IDNTDCAKLD GGMSCLSLRF
//
