ID V9W2M5_9RHOB Unreviewed; 499 AA.
AC V9W2M5;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE SubName: Full=Aldehyde dehydrogenase {ECO:0000313|EMBL:AHD03432.1};
GN ORFNames=METH_21645 {ECO:0000313|EMBL:AHD03432.1};
OS Leisingera methylohalidivorans DSM 14336.
OG Plasmid unnamed {ECO:0000313|EMBL:AHD03432.1,
OG ECO:0000313|Proteomes:UP000018780}.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC Roseobacteraceae; Leisingera.
OX NCBI_TaxID=999552 {ECO:0000313|EMBL:AHD03432.1, ECO:0000313|Proteomes:UP000018780};
RN [1] {ECO:0000313|EMBL:AHD03432.1, ECO:0000313|Proteomes:UP000018780}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 14336 {ECO:0000313|EMBL:AHD03432.1,
RC ECO:0000313|Proteomes:UP000018780};
RC PLASMID=1 {ECO:0000313|Proteomes:UP000018780};
RG DOE Joint Genome Institute;
RA Klenk H.-P., Huntemann M., Han J., Chen A., Kyrpides N., Mavromatis K.,
RA Markowitz V., Palaniappan K., Ivanova N., Schaumberg A., Pati A.,
RA Liolios K., Nordberg H.P., Cantor M.N., Hua S.X., Woyke T.;
RL Submitted (SEP-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the aldehyde dehydrogenase family.
CC {ECO:0000256|RuleBase:RU003345}.
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DR EMBL; CP006774; AHD03432.1; -; Genomic_DNA.
DR RefSeq; WP_024092728.1; NC_023146.1.
DR AlphaFoldDB; V9W2M5; -.
DR KEGG; lmd:METH_21645; -.
DR PATRIC; fig|999552.6.peg.4278; -.
DR HOGENOM; CLU_005391_0_2_5; -.
DR OrthoDB; 9812625at2; -.
DR Proteomes; UP000018780; Plasmid 1.
DR GO; GO:0016620; F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR CDD; cd07112; ALDH_GABALDH-PuuC; 1.
DR InterPro; IPR016161; Ald_DH/histidinol_DH.
DR InterPro; IPR016163; Ald_DH_C.
DR InterPro; IPR016160; Ald_DH_CS_CYS.
DR InterPro; IPR029510; Ald_DH_CS_GLU.
DR InterPro; IPR016162; Ald_DH_N.
DR InterPro; IPR015590; Aldehyde_DH_dom.
DR PANTHER; PTHR11699; ALDEHYDE DEHYDROGENASE-RELATED; 1.
DR PANTHER; PTHR11699:SF291; NADP_NAD-DEPENDENT ALDEHYDE DEHYDROGENASE PUUC; 1.
DR Pfam; PF00171; Aldedh; 1.
DR SUPFAM; SSF53720; ALDH-like; 1.
DR PROSITE; PS00070; ALDEHYDE_DEHYDR_CYS; 1.
DR PROSITE; PS00687; ALDEHYDE_DEHYDR_GLU; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000256|RuleBase:RU003345}; Plasmid {ECO:0000313|EMBL:AHD03432.1}.
FT DOMAIN 31..486
FT /note="Aldehyde dehydrogenase"
FT /evidence="ECO:0000259|Pfam:PF00171"
FT ACT_SITE 267
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10007"
SQ SEQUENCE 499 AA; 53481 MW; 05C46C3E868CECF4 CRC64;
MTLLTQDEYT SIAAGLALPT GAFIDGKFRP AASGKTFETV NPATGEKLAD IASCGAEDVD
FAVEKAREAF DDGRWSKLHP SARKDVLIRL AKLMTRQRRE LAVMESLDSG KTIYDCETVD
VPETIHCIKW HAEAIDKIYD QVAPASDDHI AMVLREPIGV AGLVLPWNFP LLMLAWKIGP
ALAAGCSVVV KPAAETTLTA LRVAELAMEA GLPRGVLNVV PGGGAEVGEP IGRHMDIDMV
SFTGSTVTGK RFLSYSAESN AKEVVLEMGG KNPAIVMDDA ESLDRVASHV VNGAFWNMGE
NCSASSRLIV HKHVKSELLE RIAHHAKQWN AGDPLDPETR MGALVSRAHF DKVCGYLEQA
GNVVLGGKSY DGAFVEPTVV EVPGNDAVLA REEIFGPVLS VIEVAGFDEA IQIANDTDYG
LCASIFTANV KRAIRGARAI RAGTVTVNSF GEGDISTPFG GYKQSGFGGR DNALQAHDQY
TQLKTIWIDL ADDTDEAVD
//
