ID V9XJK9_9NOCA Unreviewed; 266 AA.
AC V9XJK9;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 24-JAN-2024, entry version 41.
DE SubName: Full=Enoyl-CoA hydratase {ECO:0000313|EMBL:AHD21502.1};
DE EC=4.2.1.17 {ECO:0000313|EMBL:AHD21502.1};
GN ORFNames=Y013_12980 {ECO:0000313|EMBL:AHD21502.1};
OS Rhodococcus pyridinivorans SB3094.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Nocardiaceae;
OC Rhodococcus.
OX NCBI_TaxID=1435356 {ECO:0000313|EMBL:AHD21502.1, ECO:0000313|Proteomes:UP000018781};
RN [1] {ECO:0000313|EMBL:AHD21502.1, ECO:0000313|Proteomes:UP000018781}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SB3094 {ECO:0000313|EMBL:AHD21502.1,
RC ECO:0000313|Proteomes:UP000018781};
RX PubMed=24874690;
RA Dueholm M.S., Albertsen M., D'Imperio S., Tale V.P., Lewis D.,
RA Nielsen P.H., Nielsen J.L.;
RT "Complete Genome of Rhodococcus pyridinivorans SB3094, a Methyl-Ethyl-
RT Ketone-Degrading Bacterium Used for Bioaugmentation.";
RL Genome Announc. 2:e00525-14(2014).
CC -!- FUNCTION: Could possibly oxidize fatty acids using specific components.
CC {ECO:0000256|ARBA:ARBA00002994}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a (3S)-3-hydroxyacyl-CoA = a (2E)-enoyl-CoA + H2O;
CC Xref=Rhea:RHEA:16105, ChEBI:CHEBI:15377, ChEBI:CHEBI:57318,
CC ChEBI:CHEBI:58856; EC=4.2.1.17;
CC Evidence={ECO:0000256|ARBA:ARBA00023709};
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a 4-saturated-(3S)-3-hydroxyacyl-CoA = a (3E)-enoyl-CoA + H2O;
CC Xref=Rhea:RHEA:20724, ChEBI:CHEBI:15377, ChEBI:CHEBI:58521,
CC ChEBI:CHEBI:137480; EC=4.2.1.17;
CC Evidence={ECO:0000256|ARBA:ARBA00023717};
CC -!- SIMILARITY: Belongs to the enoyl-CoA hydratase/isomerase family.
CC {ECO:0000256|ARBA:ARBA00005254, ECO:0000256|RuleBase:RU003707}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP006996; AHD21502.1; -; Genomic_DNA.
DR RefSeq; WP_024102269.1; NC_023150.1.
DR AlphaFoldDB; V9XJK9; -.
DR GeneID; 29936768; -.
DR KEGG; rpy:Y013_12980; -.
DR PATRIC; fig|1435356.3.peg.2613; -.
DR eggNOG; COG1024; Bacteria.
DR HOGENOM; CLU_009834_7_2_11; -.
DR Proteomes; UP000018781; Chromosome.
DR GO; GO:0004300; F:enoyl-CoA hydratase activity; IEA:UniProtKB-EC.
DR CDD; cd06558; crotonase-like; 1.
DR Gene3D; 1.10.12.10; Lyase 2-enoyl-coa Hydratase, Chain A, domain 2; 1.
DR InterPro; IPR029045; ClpP/crotonase-like_dom_sf.
DR InterPro; IPR018376; Enoyl-CoA_hyd/isom_CS.
DR InterPro; IPR001753; Enoyl-CoA_hydra/iso.
DR InterPro; IPR014748; Enoyl-CoA_hydra_C.
DR PANTHER; PTHR43459:SF1; EG:BACN32G11.4 PROTEIN; 1.
DR PANTHER; PTHR43459; ENOYL-COA HYDRATASE; 1.
DR Pfam; PF00378; ECH_1; 1.
DR SUPFAM; SSF52096; ClpP/crotonase; 1.
DR PROSITE; PS00166; ENOYL_COA_HYDRATASE; 1.
PE 3: Inferred from homology;
KW Lyase {ECO:0000313|EMBL:AHD21502.1}.
SQ SEQUENCE 266 AA; 28329 MW; BFC751962B4046D3 CRC64;
MENPVLVERD GFIETWTINR PAERNPVSGM DVVDALVACV DAVNADYGVR AVIVTGAGST
FSAGGNVKDM ANRQGLFGGK PHEQRDGYRA GIQRIPRAMY NCDVPLIAAV NGPAIGAGCD
LALMCDLRIA SEKAFFAESF VKLGIIPGDG GAWLLPKAVG MARAAEMILT GDRVDATQAL
EWGLVSNVVP PDQLLDEARA LANRVAANPP HSVRMAKKLL REGQHQSLDS LLELSAALQA
LVQQTTDHTR AVNALMEKRT AAFTGE
//
