ID   V9Y1Y5_9NEOP            Unreviewed;       240 AA.
AC   V9Y1Y5;
DT   19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT   19-MAR-2014, sequence version 1.
DT   27-MAR-2024, entry version 26.
DE   SubName: Full=Isocitrate dehydrogenase {ECO:0000313|EMBL:AHE14310.1};
DE   Flags: Fragment;
GN   Name=IDH {ECO:0000313|EMBL:AHE14310.1};
OS   Beraeamyia squamosa.
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Trichoptera; Integripalpia; Brevitentoria;
OC   Sericostomatoidea; Anomalopsychidae; Beraeamyia.
OX   NCBI_TaxID=626973 {ECO:0000313|EMBL:AHE14310.1};
RN   [1] {ECO:0000313|EMBL:AHE14310.1}
RP   NUCLEOTIDE SEQUENCE.
RA   Malm T., Johanson K.A., Wahlberg N.;
RT   "The evolutionary history of Trichoptera (Insecta): A case of successful
RT   adaptation to life in freshwater.";
RL   Submitted (FEB-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC         Evidence={ECO:0000256|ARBA:ARBA00001946};
CC   -!- COFACTOR:
CC       Name=Mn(2+); Xref=ChEBI:CHEBI:29035;
CC         Evidence={ECO:0000256|ARBA:ARBA00001936};
CC   -!- SIMILARITY: Belongs to the isocitrate and isopropylmalate
CC       dehydrogenases family. {ECO:0000256|ARBA:ARBA00007769}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; KC559619; AHE14310.1; -; Genomic_DNA.
DR   AlphaFoldDB; V9Y1Y5; -.
DR   GO; GO:0004450; F:isocitrate dehydrogenase (NADP+) activity; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006097; P:glyoxylate cycle; IEA:UniProtKB-KW.
DR   GO; GO:0006102; P:isocitrate metabolic process; IEA:InterPro.
DR   GO; GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.718.10; Isopropylmalate Dehydrogenase; 1.
DR   InterPro; IPR004790; Isocitrate_DH_NADP.
DR   InterPro; IPR024084; IsoPropMal-DH-like_dom.
DR   NCBIfam; TIGR00127; nadp_idh_euk; 1.
DR   PANTHER; PTHR11822:SF21; ISOCITRATE DEHYDROGENASE [NADP], MITOCHONDRIAL; 1.
DR   PANTHER; PTHR11822; NADP-SPECIFIC ISOCITRATE DEHYDROGENASE; 1.
DR   Pfam; PF00180; Iso_dh; 1.
DR   SMART; SM01329; Iso_dh; 1.
DR   SUPFAM; SSF53659; Isocitrate/Isopropylmalate dehydrogenase-like; 1.
PE   3: Inferred from homology;
KW   Glyoxylate bypass {ECO:0000256|ARBA:ARBA00022435};
KW   Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW   Manganese {ECO:0000256|ARBA:ARBA00023211};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW   Tricarboxylic acid cycle {ECO:0000256|ARBA:ARBA00022532}.
FT   DOMAIN          1..239
FT                   /note="Isopropylmalate dehydrogenase-like"
FT                   /evidence="ECO:0000259|SMART:SM01329"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:AHE14310.1"
FT   NON_TER         240
FT                   /evidence="ECO:0000313|EMBL:AHE14310.1"
SQ   SEQUENCE   240 AA;  27426 MW;  240BBD06105E37EC CRC64;
     DLIKDKLILP FLDIELHTYD LGIEYRDKTE DQVTIDCANA ILKYNVGIKC ATITPDEKRV
     EEFKLKKMWK SPNGTIRNIL GGTVFREAII CKNIPRLVSG WEKPIIIGRH AHADQYKATD
     FVVPGAGKLE LIWTASAGNS EAPINFVVHE YSGPGVALAM YNTDDSITDF AHSSFKYALD
     RKYPLYLSTK NTILKKYDGR FKDIFQVIYE KDYKTQFEAA GIWYEHRLID DMVAYALKSE
//