ID   V9Z8J8_NASOF            Unreviewed;       297 AA.
AC   V9Z8J8;
DT   19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT   19-MAR-2014, sequence version 1.
DT   08-NOV-2023, entry version 21.
DE   SubName: Full=Fatty acid elongase 1 {ECO:0000313|EMBL:AHE40838.1};
DE   Flags: Fragment;
GN   Name=FAE1 {ECO:0000313|EMBL:AHE40838.1};
OS   Nasturtium officinale (Watercress) (Rorippa nasturtium-aquaticum).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Cardamineae; Nasturtium.
OX   NCBI_TaxID=65948 {ECO:0000313|EMBL:AHE40838.1};
RN   [1] {ECO:0000313|EMBL:AHE40838.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=59-A {ECO:0000313|EMBL:AHE40838.1};
RX   PubMed=24358289;
RA   Sun X., Pang H., Li M., Peng B., Guo H., Yan Q., Hang Y.;
RT   "Evolutionary Pattern of the FAE1 Gene in Brassicaceae and Its Correlation
RT   with the Erucic Acid Trait.";
RL   PLoS ONE 8:E83535-E83535(2013).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a very-long-chain acyl-CoA + H(+) + malonyl-CoA = a very-long-
CC         chain 3-oxoacyl-CoA + CO2 + CoA; Xref=Rhea:RHEA:32727,
CC         ChEBI:CHEBI:15378, ChEBI:CHEBI:16526, ChEBI:CHEBI:57287,
CC         ChEBI:CHEBI:57384, ChEBI:CHEBI:90725, ChEBI:CHEBI:90736;
CC         EC=2.3.1.199; Evidence={ECO:0000256|ARBA:ARBA00001906};
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DR   EMBL; KF030552; AHE40838.1; -; Genomic_DNA.
DR   AlphaFoldDB; V9Z8J8; -.
DR   GO; GO:0016020; C:membrane; IEA:InterPro.
DR   GO; GO:0009922; F:fatty acid elongase activity; IEA:UniProtKB-EC.
DR   GO; GO:0006633; P:fatty acid biosynthetic process; IEA:InterPro.
DR   CDD; cd00831; CHS_like; 1.
DR   Gene3D; 3.40.47.10; -; 1.
DR   InterPro; IPR012392; 3-ktacl-CoA_syn.
DR   InterPro; IPR012328; Chalcone/stilbene_synt_C.
DR   InterPro; IPR013601; FAE1_typ3_polyketide_synth.
DR   InterPro; IPR016039; Thiolase-like.
DR   PANTHER; PTHR31561; 3-KETOACYL-COA SYNTHASE; 1.
DR   PANTHER; PTHR31561:SF88; 3-KETOACYL-COA SYNTHASE 18; 1.
DR   Pfam; PF02797; Chal_sti_synt_C; 1.
DR   Pfam; PF08392; FAE1_CUT1_RppA; 1.
DR   SUPFAM; SSF53901; Thiolase-like; 2.
PE   4: Predicted;
FT   DOMAIN          2..224
FT                   /note="FAE"
FT                   /evidence="ECO:0000259|Pfam:PF08392"
FT   DOMAIN          244..294
FT                   /note="Chalcone/stilbene synthase C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF02797"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:AHE40838.1"
FT   NON_TER         297
FT                   /evidence="ECO:0000313|EMBL:AHE40838.1"
SQ   SEQUENCE   297 AA;  32596 MW;  19EED795882F0DAD CRC64;
     LIQVPPLKNF AAAHEETEQV IVGALEKLFE NTKVNPREIG ILVVNSSMFN PTPSLSAMVV
     NTFKLRSNIK SFSLGGMGCS AGIIAIDLAK DLLHVHKDTY ALVVSTENIT YGIYAGNNRS
     MMVSNCLFRV GGAAILLSNK PGDRRRSKYK LAHTVRTHTG ADDQSFRCVR QEDDESGKIG
     VCLSKDITAV AGRTVKKNIA TLGPLVLPLS EKFLFFVTFV AKKLFKDKIK HYYVPDFKLA
     IDHFCIHAGG RAVIDVLEKN LGLSSVDVEA SRSTLHRFGN TSSSSIWYEL AYIEAKG
//