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Database: UniProt
Entry: W0H2U1_PSECI
LinkDB: W0H2U1_PSECI
Original site: W0H2U1_PSECI 
ID   W0H2U1_PSECI            Unreviewed;       500 AA.
AC   W0H2U1;
DT   19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT   19-MAR-2014, sequence version 1.
DT   05-JUL-2017, entry version 27.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00724181};
GN   Name=dnaA {ECO:0000256|HAMAP-Rule:MF_00377};
GN   ORFNames=PCH70_00040 {ECO:0000313|EMBL:AHF65157.1};
OS   Pseudomonas cichorii JBC1.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC   Pseudomonadaceae; Pseudomonas.
OX   NCBI_TaxID=1441629 {ECO:0000313|EMBL:AHF65157.1, ECO:0000313|Proteomes:UP000019031};
RN   [1] {ECO:0000313|EMBL:AHF65157.1, ECO:0000313|Proteomes:UP000019031}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JBC1 {ECO:0000313|EMBL:AHF65157.1,
RC   ECO:0000313|Proteomes:UP000019031};
RA   Kim B.-Y., Lee Y.H.;
RT   "Analysis of whole genome sequence of Pseudomonas cichorii JBC1.";
RL   Submitted (JAN-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00724167}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS00756131}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
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DR   EMBL; CP007039; AHF65157.1; -; Genomic_DNA.
DR   EnsemblBacteria; AHF65157; AHF65157; PCH70_00040.
DR   KEGG; pci:PCH70_00040; -.
DR   PATRIC; fig|1441629.3.peg.4; -.
DR   KO; K02313; -.
DR   Proteomes; UP000019031; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-HAMAP.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-HAMAP.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR024633; DnaA_N_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF12; PTHR30050:SF12; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   Pfam; PF11638; DnaA_N; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00731922};
KW   Complete proteome {ECO:0000313|Proteomes:UP000019031};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS00756112};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00731887};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756124};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00731897};
KW   Reference proteome {ECO:0000313|Proteomes:UP000019031}.
FT   DOMAIN      197    402       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      408    477       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
FT   NP_BIND     205    212       ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   500 AA;  55877 MW;  07DD0B356DA10E1F CRC64;
     MELLRDELPA QQFNTWIRPL QVEAEGDELR VYAPNRFVLD WVNEKYLSRL LELLGEHGQG
     MAPALSLLIG SKRSSAPRAA PNAPLAAAAS QALSANNVSS VSTPVAAPVV AAPAPAPAVQ
     NAETHDEPSR DSFDPMAGAS SQQAPARAEQ RTVQVEGALK HTSYLNRTFT FENFVEGKSN
     QLARAAAWQV ADNPKHGYNP LFLYGGVGLG KTHLMHAVGN HLLKKNPNAK VVYLHSERFV
     ADMVKALQLN AINEFKRFYR SVDALLIDDI QFFARKERSQ EEFFHTFNAL LEGGQQVILT
     SDRYPKEIEG LEERLKSRFG WGLTVAVEPP ELETRVAILM KKADQAKVEL PHDAAFFIAQ
     RIRSNVRELE GALKRVIAHS HFMGRDITIE LIRESLKDLL ALQDKLVSVD NIQRTVAEYY
     KIKISDLLSK RRSRSVARPR QVAMALSKEL TNHSLPEIGD VFGGRDHTTV LHACRKINEL
     KESDADIRED YKNLLRTLTT
//
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