ID W0HQ58_9GAMM Unreviewed; 643 AA.
AC W0HQ58;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE RecName: Full=beta-N-acetylhexosaminidase {ECO:0000256|ARBA:ARBA00012663};
DE EC=3.2.1.52 {ECO:0000256|ARBA:ARBA00012663};
GN ORFNames=Sant_0881 {ECO:0000313|EMBL:AHF75961.1};
OS Sodalis praecaptivus.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Bruguierivoracaceae; Sodalis.
OX NCBI_TaxID=1239307 {ECO:0000313|EMBL:AHF75961.1, ECO:0000313|Proteomes:UP000019028};
RN [1] {ECO:0000313|EMBL:AHF75961.1, ECO:0000313|Proteomes:UP000019028}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HS1 {ECO:0000313|EMBL:AHF75961.1,
RC ECO:0000313|Proteomes:UP000019028};
RX PubMed=24407854; DOI=10.1093/gbe/evt210;
RA Oakeson K.F., Gil R., Clayton A.L., Dunn D.M., von Niederhausern A.C.,
RA Hamil C., Aoyagi A., Duval B., Baca A., Silva F.J., Vallier A.,
RA Jackson D.G., Latorre A., Weiss R.B., Heddi A., Moya A., Dale C.;
RT "Genome degeneration and adaptation in a nascent stage of symbiosis.";
RL Genome Biol. Evol. 6:76-93(2014).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Hydrolysis of terminal non-reducing N-acetyl-D-hexosamine
CC residues in N-acetyl-beta-D-hexosaminides.; EC=3.2.1.52;
CC Evidence={ECO:0000256|ARBA:ARBA00001231};
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 3 family.
CC {ECO:0000256|ARBA:ARBA00005336, ECO:0000256|RuleBase:RU361161}.
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DR EMBL; CP006569; AHF75961.1; -; Genomic_DNA.
DR AlphaFoldDB; W0HQ58; -.
DR KEGG; sod:Sant_0881; -.
DR PATRIC; fig|1239307.3.peg.946; -.
DR HOGENOM; CLU_008392_5_2_6; -.
DR Proteomes; UP000019028; Chromosome.
DR GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR Gene3D; 3.40.50.1700; Glycoside hydrolase family 3 C-terminal domain; 1.
DR Gene3D; 3.20.20.300; Glycoside hydrolase, family 3, N-terminal domain; 1.
DR InterPro; IPR019800; Glyco_hydro_3_AS.
DR InterPro; IPR002772; Glyco_hydro_3_C.
DR InterPro; IPR036881; Glyco_hydro_3_C_sf.
DR InterPro; IPR001764; Glyco_hydro_3_N.
DR InterPro; IPR036962; Glyco_hydro_3_N_sf.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR PANTHER; PTHR30480:SF13; BETA-HEXOSAMINIDASE; 1.
DR PANTHER; PTHR30480; BETA-HEXOSAMINIDASE-RELATED; 1.
DR Pfam; PF00933; Glyco_hydro_3; 1.
DR Pfam; PF01915; Glyco_hydro_3_C; 1.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF52279; Beta-D-glucan exohydrolase, C-terminal domain; 1.
DR PROSITE; PS00775; GLYCOSYL_HYDROL_F3; 1.
PE 3: Inferred from homology;
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295, ECO:0000256|RuleBase:RU361161};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU361161};
KW Reference proteome {ECO:0000313|Proteomes:UP000019028}.
FT DOMAIN 57..414
FT /note="Glycoside hydrolase family 3 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00933"
FT DOMAIN 450..628
FT /note="Glycoside hydrolase family 3 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF01915"
SQ SEQUENCE 643 AA; 70151 MW; 522602CC0CC17AF2 CRC64;
MMTAPCLPRA REHMMNTIPP TRVTGVAAVT TQTPRANALG QALTRADNSQ SVLAGMTLRE
KIGQKIMLDF RYWGRDSASG AARDTVALNA CIENILRDYH IGGVILFANN LKDADQIRRL
TGQLAAVPQT HGIGLLIGTD NEGGNVFRLP RGDYTAFAGN MALGALYEGH GESALPYLQG
KIMAQELCSL GLNLNFAPVV DVNSNQANPV INVRAFGDCP AQVDRLARQM VKGSAQIVTC
YKHFPGHGDT HTDSHLNLPR VDRNREQAFA VDLAPYIAAI ADNDAPDMIM TAHIQYPALD
DSLITRLDGE DIIVPATLSR RIQHHLLRQE MGYRGVTITD ALDMKAISDH FDPRDVVKRV
FNAGVDIALM PVSVQAADEE DKLRELIDYI VAQVERGEID CEEIDVSVAR ILTLKRAKNI
LAGQAASAAI GETERRLAKE VESAIADQSI TLLQNHQLLP LRDVSRRIAI FTPWGEQGHA
VRQVLQQKGF HDVSSHKIDE IAWQAQRQEI DRCDIVIVGS QAVGVSPVEN NGQASGANGT
GDTAHIAAII DYAHRQQKKI VLLLMRSPYD IIHFDGKTDA IVATYAYYGL DNGVRRGESL
FAAARALVGD LKPSGKLPVN IYNVDPQGAI TDIRYPRGFG LNG
//
