ID W0IY33_9BACT Unreviewed; 744 AA.
AC W0IY33;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE RecName: Full=Beta-galactosidase {ECO:0000256|RuleBase:RU000675};
DE EC=3.2.1.23 {ECO:0000256|RuleBase:RU000675};
GN ORFNames=OPIT5_02880 {ECO:0000313|EMBL:AHF89364.1};
OS Opitutaceae bacterium TAV5.
OC Bacteria; Verrucomicrobiota; Opitutae; Opitutales; Opitutaceae.
OX NCBI_TaxID=794903 {ECO:0000313|EMBL:AHF89364.1, ECO:0000313|Proteomes:UP000003813};
RN [1] {ECO:0000313|EMBL:AHF89364.1, ECO:0000313|Proteomes:UP000003813}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=TAV5 {ECO:0000313|EMBL:AHF89364.1};
RX PubMed=25744998;
RA Kotak M., Isanapong J., Goodwin L., Bruce D., Chen A., Han C.S.,
RA Huntemann M., Ivanova N., Land M.L., Nolan M., Pati A., Woyke T.,
RA Rodrigues J.L.;
RT "Complete Genome Sequence of the Opitutaceae Bacterium Strain TAV5, a
RT Potential Facultative Methylotroph of the Wood-Feeding Termite
RT Reticulitermes flavipes.";
RL Genome Announc. 3:0-0(2015).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Hydrolysis of terminal non-reducing beta-D-galactose residues
CC in beta-D-galactosides.; EC=3.2.1.23;
CC Evidence={ECO:0000256|RuleBase:RU000675};
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 35 family.
CC {ECO:0000256|ARBA:ARBA00009809, ECO:0000256|RuleBase:RU003679}.
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DR EMBL; CP007053; AHF89364.1; -; Genomic_DNA.
DR AlphaFoldDB; W0IY33; -.
DR STRING; 794903.OPIT5_02880; -.
DR KEGG; obt:OPIT5_02880; -.
DR eggNOG; COG1874; Bacteria.
DR HOGENOM; CLU_007853_4_0_0; -.
DR OrthoDB; 9813184at2; -.
DR Proteomes; UP000003813; Chromosome.
DR GO; GO:0004565; F:beta-galactosidase activity; IEA:UniProtKB-EC.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 2.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR InterPro; IPR048913; BetaGal_gal-bd.
DR InterPro; IPR008979; Galactose-bd-like_sf.
DR InterPro; IPR031330; Gly_Hdrlase_35_cat.
DR InterPro; IPR019801; Glyco_hydro_35_CS.
DR InterPro; IPR001944; Glycoside_Hdrlase_35.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR PANTHER; PTHR23421:SF124; BETA-GALACTOSIDASE 2-RELATED; 1.
DR PANTHER; PTHR23421; BETA-GALACTOSIDASE RELATED; 1.
DR Pfam; PF21467; BetaGal_gal-bd; 1.
DR Pfam; PF01301; Glyco_hydro_35; 1.
DR PRINTS; PR00742; GLHYDRLASE35.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF49785; Galactose-binding domain-like; 1.
DR PROSITE; PS01182; GLYCOSYL_HYDROL_F35; 1.
PE 3: Inferred from homology;
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295, ECO:0000256|RuleBase:RU000675};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU000675};
KW Reference proteome {ECO:0000313|Proteomes:UP000003813}.
FT DOMAIN 10..324
FT /note="Glycoside hydrolase 35 catalytic"
FT /evidence="ECO:0000259|Pfam:PF01301"
FT DOMAIN 639..718
FT /note="Beta-galactosidase galactose-binding"
FT /evidence="ECO:0000259|Pfam:PF21467"
SQ SEQUENCE 744 AA; 82698 MW; 93179811744A25A2 CRC64;
MTVSFDHRAL LLDGRRTLVL SGAVHYPRST PAMWPRILRH MRQSGLNTVE TYIFWNLHER
RRGVLDFSGR LDLVRFCRLA QAEGLNVILR IGPYICAETN YGGLPGWLRD VPDIRMRTDN
EAFKREKARW VRLVAEVIRP LCAPNGGPVI LAQIENEYDN IAATYGEDGR RYLRWSVELA
QSLGLGIPWV TCAAGRAAEA GEKDAVASAG DSLETLNAFR AHEIIGQHFR EHPEQPALWT
ENWAGWYQTW GGVLPKREPE ELAYATARFF AAGGSGVNYF LWHGGTNFGR DGMYLLTTAY
EFGGPLDEYG LPTTKARHLA RLNKALAACA DKILASERPR AITGERNGLL KFQYSSGLTF
WCDDVARTVR IVGKNGEVLY DSSARVAPVR RTWKASGVRF APWGWRAEPL PAAWPAEAQS
AVTARKPLEQ LLLTKDETDY CWYETAIVVE GSGDVLVAGR DGSPAGLERG ALARVGRRGR
RPSIAGLASE VPANTVNTLR LTRVADIVHV FIDGTFVATT PTPLRERRGK MDAGLFTQTF
ELDLKALRIT PGKHRLSLLC CALGLIKGDW MIGYENMALE KKGLWAPVFW NGKKLEGEWR
HQPGLLGERC GFADPAAGSL LAWKTAKAAT GRGARRPLRW WRTTFTRPKG HGPWALDLGG
MGKGMAWING HCIGRYWLLA DTDPMGPWMA WMKGSLTAAP SSGPTQRYYH VPDDWLRTDG
GPDTLVLFEE LGGDPATVRL VRRE
//
