ID W0JQX3_9EURY Unreviewed; 198 AA.
AC W0JQX3;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE RecName: Full=dihydrofolate reductase {ECO:0000256|ARBA:ARBA00012856};
DE EC=1.5.1.3 {ECO:0000256|ARBA:ARBA00012856};
GN ORFNames=HALLA_11335 {ECO:0000313|EMBL:AHF99367.1};
OS Halostagnicola larsenii XH-48.
OC Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Natrialbales;
OC Natrialbaceae; Halostagnicola.
OX NCBI_TaxID=797299 {ECO:0000313|EMBL:AHF99367.1, ECO:0000313|Proteomes:UP000019024};
RN [1] {ECO:0000313|EMBL:AHF99367.1, ECO:0000313|Proteomes:UP000019024}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=XH-48 {ECO:0000313|EMBL:AHF99367.1,
RC ECO:0000313|Proteomes:UP000019024};
RG DOE Joint Genome Institute;
RA Anderson I., Huntemann M., Han J., Chen A., Kyrpides N., Mavromatis K.,
RA Markowitz V., Palaniappan K., Ivanova N., Schaumberg A., Pati A.,
RA Liolios K., Nordberg H.P., Cantor M.N., Hua S.X., Woyke T.;
RL Submitted (JAN-2014) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP007055; AHF99367.1; -; Genomic_DNA.
DR AlphaFoldDB; W0JQX3; -.
DR STRING; 797299.HALLA_11335; -.
DR KEGG; hlr:HALLA_11335; -.
DR PATRIC; fig|797299.3.peg.1300; -.
DR eggNOG; arCOG01490; Archaea.
DR HOGENOM; CLU_043966_5_1_2; -.
DR OrthoDB; 198183at2157; -.
DR Proteomes; UP000019024; Chromosome.
DR GO; GO:0004146; F:dihydrofolate reductase activity; IEA:UniProtKB-EC.
DR GO; GO:0050661; F:NADP binding; IEA:InterPro.
DR GO; GO:0006545; P:glycine biosynthetic process; IEA:InterPro.
DR GO; GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
DR GO; GO:0046654; P:tetrahydrofolate biosynthetic process; IEA:InterPro.
DR CDD; cd00209; DHFR; 1.
DR Gene3D; 3.40.430.10; Dihydrofolate Reductase, subunit A; 1.
DR InterPro; IPR012259; DHFR.
DR InterPro; IPR024072; DHFR-like_dom_sf.
DR InterPro; IPR001796; DHFR_dom.
DR PANTHER; PTHR48069; DIHYDROFOLATE REDUCTASE; 1.
DR PANTHER; PTHR48069:SF3; DIHYDROFOLATE REDUCTASE; 1.
DR Pfam; PF00186; DHFR_1; 1.
DR PIRSF; PIRSF000194; DHFR; 1.
DR PRINTS; PR00070; DHFR.
DR SUPFAM; SSF53597; Dihydrofolate reductase-like; 1.
DR PROSITE; PS51330; DHFR_2; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000019024}.
FT DOMAIN 31..198
FT /note="DHFR"
FT /evidence="ECO:0000259|PROSITE:PS51330"
SQ SEQUENCE 198 AA; 21577 MW; 63583796A52BE559 CRC64;
MSGGDERTGA DDAGPNEVDV TDAEALETDC ELVAIVAVAD NGIIGRDGDM PWHIPADLEH
FKETTIDHPV IMGRVTYEGI LEALGEPLPG RTTVVLTSQD LETPENAVTA AGIEGALEAA
ETAARDRHDD ADRIFVAGGA TVYEQFLPVV DRLIVTEVHE EPAGDTSFPA WDREAWNERA
RDERDGFAFV EYGRRRME
//
