ID W0MMU0_PSESX Unreviewed; 460 AA.
AC W0MMU0;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 27-MAR-2024, entry version 53.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=N018_05675 {ECO:0000313|EMBL:AHG39757.1};
OS Pseudomonas syringae CC1557.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales;
OC Pseudomonadaceae; Pseudomonas; Pseudomonas syringae.
OX NCBI_TaxID=1357279 {ECO:0000313|EMBL:AHG39757.1, ECO:0000313|Proteomes:UP000019089};
RN [1] {ECO:0000313|EMBL:AHG39757.1, ECO:0000313|Proteomes:UP000019089}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CC1557 {ECO:0000313|EMBL:AHG39757.1,
RC ECO:0000313|Proteomes:UP000019089};
RA Baltrus D., Hockett K., Karlsrud E., Dougherty K., Nishimura M.;
RT "Interactions Between Genome Architecture and Virulence Genes in
RT Pseudomonas syringae, strain CC1557 as a model.";
RL Submitted (DEC-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
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DR EMBL; CP007014; AHG39757.1; -; Genomic_DNA.
DR RefSeq; WP_025389054.1; NZ_CP007014.1.
DR AlphaFoldDB; W0MMU0; -.
DR STRING; 1357279.N018_05675; -.
DR KEGG; psyr:N018_05675; -.
DR eggNOG; COG5002; Bacteria.
DR HOGENOM; CLU_000445_89_37_6; -.
DR Proteomes; UP000019089; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd00075; HATPase; 1.
DR CDD; cd00082; HisKA; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR InterPro; IPR013727; 2CSK_N.
DR InterPro; IPR003660; HAMP_dom.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR PANTHER; PTHR45436:SF15; SENSOR HISTIDINE KINASE CRDS; 1.
DR PANTHER; PTHR45436; SENSOR HISTIDINE KINASE YKOH; 1.
DR Pfam; PF08521; 2CSK_N; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR PROSITE; PS50885; HAMP; 1.
DR PROSITE; PS50109; HIS_KIN; 1.
PE 4: Predicted;
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:AHG39757.1};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW Two-component regulatory system {ECO:0000256|ARBA:ARBA00023012}.
FT TRANSMEM 12..31
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 171..193
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 190..242
FT /note="HAMP"
FT /evidence="ECO:0000259|PROSITE:PS50885"
FT DOMAIN 250..460
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
SQ SEQUENCE 460 AA; 50735 MW; E8A4A01D7626B49E CRC64;
MINDSLRWRL LWNLALLLVV LMLASGMSAY WNGREVADTA YDRTLLASAR TIAAGLTQRD
GTLSADIPYV ALDTFAYDSE GRIYYQVNDI HQKLISGYEN LPSPPPGTLR TDDYPALAKF
YNGTYQGQDV RVVSLLKPVT DPGMNGTAEI RVAETQEARK GMARSLMADT LLRLGMLGGG
ALLLVWFTVS AALRPLERLR TSVEERQPDD LRALPMVEVQ HELRPLVGAL NHFTERLRLQ
FERQAQFIAD AAHELRTPLA ALKARVELGL RERDPQRWRE TLESAALGTD RLTQLANQLL
SLARIENGAR AIAEGGAQQL DLSQLARELG MAMAPLAHSR GVALALEADE PVWLRGEPTL
LNELLSNLID NALAHTLPGG NVVLRVYAPG VLEVEDDGPG IPPEERERVF ERFYRRSQQG
CGAGLGLAIV GEICRAHLAR ITLHDGAERG LKVRVSFTMS
//
