ID W0R5E2_BIBTR Unreviewed; 503 AA.
AC W0R5E2;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 24-JAN-2024, entry version 36.
DE RecName: Full=Nicotinamide phosphoribosyltransferase {ECO:0000256|ARBA:ARBA00035036};
DE EC=2.4.2.12 {ECO:0000256|ARBA:ARBA00035024};
GN ORFNames=F544_11210 {ECO:0000313|EMBL:AHG86349.1};
OS Bibersteinia trehalosi USDA-ARS-USMARC-190.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Pasteurellales;
OC Pasteurellaceae; Bibersteinia.
OX NCBI_TaxID=1263832 {ECO:0000313|EMBL:AHG86349.1, ECO:0000313|Proteomes:UP000019086};
RN [1] {ECO:0000313|EMBL:AHG86349.1, ECO:0000313|Proteomes:UP000019086}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=USDA-ARS-USMARC-190 {ECO:0000313|EMBL:AHG86349.1,
RC ECO:0000313|Proteomes:UP000019086};
RA Harhay G.P., McVey S., Clawson M.L., Bono J., Heaton M.P.,
RA Chitko-Mckown C.G., Harhay D.M., Smith T.P.L.;
RT "Annotation of the Bibersteinia trehalosi USDA-ARS-USMARC-190 complete
RT genome.";
RL Submitted (DEC-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- PATHWAY: Cofactor biosynthesis; NAD(+) biosynthesis; nicotinamide D-
CC ribonucleotide from 5-phospho-alpha-D-ribose 1-diphosphate and
CC nicotinamide: step 1/1. {ECO:0000256|ARBA:ARBA00035007}.
CC -!- SIMILARITY: Belongs to the NAPRTase family.
CC {ECO:0000256|ARBA:ARBA00010897}.
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DR EMBL; CP006956; AHG86349.1; -; Genomic_DNA.
DR RefSeq; WP_025289331.1; NZ_CP006956.1.
DR AlphaFoldDB; W0R5E2; -.
DR SMR; W0R5E2; -.
DR KEGG; btra:F544_11210; -.
DR PATRIC; fig|1263832.3.peg.1112; -.
DR HOGENOM; CLU_012550_2_0_6; -.
DR Proteomes; UP000019086; Chromosome.
DR GO; GO:0016757; F:glycosyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0009435; P:NAD biosynthetic process; IEA:InterPro.
DR CDD; cd01569; PBEF_like; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR041529; DUF5598.
DR InterPro; IPR041525; N/Namide_PRibTrfase.
DR InterPro; IPR016471; Nicotinamide_PRibTrfase.
DR InterPro; IPR036068; Nicotinate_pribotase-like_C.
DR PANTHER; PTHR43816; NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE; 1.
DR PANTHER; PTHR43816:SF1; NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE; 1.
DR Pfam; PF18127; NAMPT_N; 1.
DR Pfam; PF04095; NAPRTase; 1.
DR PIRSF; PIRSF005943; NMPRT; 1.
DR SUPFAM; SSF51690; Nicotinate/Quinolinate PRTase C-terminal domain-like; 1.
PE 3: Inferred from homology;
KW Glycosyltransferase {ECO:0000256|ARBA:ARBA00022676};
KW Pyridine nucleotide biosynthesis {ECO:0000256|ARBA:ARBA00022642};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:AHG86349.1}.
FT DOMAIN 16..118
FT /note="Nicotinamide phosphoribosyltransferase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF18127"
FT DOMAIN 191..457
FT /note="Nicotinate/nicotinamide phosphoribosyltransferase"
FT /evidence="ECO:0000259|Pfam:PF04095"
SQ SEQUENCE 503 AA; 56224 MW; 68168709E6D3B931 CRC64;
MLHFCNKTAK TTAIPILLCD FYKISHRLQY PVGSQFIYST LTPRSNKLAP HLDRVVPFGF
QAFIEKYLIH YFNENFFSRQ EADVVQEYSA FIKRTLGFID DGAHIAALHR LGYLPLKIKA
IAEGLSVGLK VPVMTIENTH PDFFWLTNYL ETLINVSLWQ PMVSASIARR YRLTLTEFAR
QTCDETNHVA YQSHDFSMRG MSSLESAETS GAGHLTAFVG TDTIPAISYI EHYYGCNQLI
GTSIPATEHS VMSAHGLDEL PTFRYLMAQH PDSMLSIVAD TTDFWHNITV NLPILKAEIL
ARPAQAKIII RPDSGDSFKI ICGDPNAATE HERKGLIECL WDIFGGHVNH KGYKVLDSHI
GAIYGDGVNF AKMVRILEGL KAKGFASENL VFGVGSLTYQ NNTRDTLGFA TKATAITING
QEKAIFKDPK TDNGLKKSQK GRVKVLSRDS YIDGLNANSD FSDDLLETIF ENGKLLKRVT
FEQVRANLAL DFAEKMENLS ACE
//
