ID W0RRZ0_9BACT Unreviewed; 621 AA.
AC W0RRZ0;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 27-MAR-2024, entry version 42.
DE RecName: Full=Selenocysteine-specific elongation factor {ECO:0000256|ARBA:ARBA00015953};
DE AltName: Full=SelB translation factor {ECO:0000256|ARBA:ARBA00031615};
GN ORFNames=J421_5941 {ECO:0000313|EMBL:AHG93476.1};
OS Gemmatirosa kalamazoonensis.
OG Plasmid 2 {ECO:0000313|EMBL:AHG93476.1, ECO:0000313|Proteomes:UP000019151}.
OC Bacteria; Gemmatimonadota; Gemmatimonadetes; Gemmatimonadales;
OC Gemmatimonadaceae; Gemmatirosa.
OX NCBI_TaxID=861299 {ECO:0000313|EMBL:AHG93476.1, ECO:0000313|Proteomes:UP000019151};
RN [1] {ECO:0000313|EMBL:AHG93476.1, ECO:0000313|Proteomes:UP000019151}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KBS708 {ECO:0000313|EMBL:AHG93476.1,
RC ECO:0000313|Proteomes:UP000019151};
RC PLASMID=Plasmid 2 {ECO:0000313|Proteomes:UP000019151};
RX PubMed=24699952;
RA Debruyn J.M., Radosevich M., Wommack K.E., Polson S.W., Hauser L.J.,
RA Fawaz M.N., Korlach J., Tsai Y.C.;
RT "Genome Sequence and Methylome of Soil Bacterium Gemmatirosa
RT kalamazoonensis KBS708T, a Member of the Rarely Cultivated Gemmatimonadetes
RT Phylum.";
RL Genome Announc. 2:e00226-14(2014).
CC -!- FUNCTION: Translation factor necessary for the incorporation of
CC selenocysteine into proteins. It probably replaces EF-Tu for the
CC insertion of selenocysteine directed by the UGA codon. SelB binds GTP
CC and GDP. {ECO:0000256|ARBA:ARBA00025526}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
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DR EMBL; CP007130; AHG93476.1; -; Genomic_DNA.
DR AlphaFoldDB; W0RRZ0; -.
DR KEGG; gba:J421_5941; -.
DR PATRIC; fig|861299.3.peg.5992; -.
DR eggNOG; COG3276; Bacteria.
DR HOGENOM; CLU_023030_3_0_0; -.
DR InParanoid; W0RRZ0; -.
DR OrthoDB; 9804504at2; -.
DR Proteomes; UP000019151; Plasmid 2.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-KW.
DR GO; GO:0001514; P:selenocysteine incorporation; IEA:InterPro.
DR CDD; cd04171; SelB; 1.
DR Gene3D; 1.10.10.2770; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 2.40.30.10; Translation factors; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR004161; EFTu-like_2.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR015191; SelB_WHD4.
DR InterPro; IPR000795; T_Tr_GTP-bd_dom.
DR InterPro; IPR009000; Transl_B-barrel_sf.
DR InterPro; IPR009001; Transl_elong_EF1A/Init_IF2_C.
DR InterPro; IPR004535; Transl_elong_SelB.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR NCBIfam; TIGR00475; selB; 1.
DR PANTHER; PTHR43721:SF22; ELONGATION FACTOR TU, MITOCHONDRIAL; 1.
DR PANTHER; PTHR43721; ELONGATION FACTOR TU-RELATED; 1.
DR Pfam; PF00009; GTP_EFTU; 1.
DR Pfam; PF03144; GTP_EFTU_D2; 1.
DR Pfam; PF09107; SelB-wing_3; 1.
DR SUPFAM; SSF50465; EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF50447; Translation proteins; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS51722; G_TR_2; 1.
PE 4: Predicted;
KW Elongation factor {ECO:0000313|EMBL:AHG93476.1};
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Plasmid {ECO:0000313|EMBL:AHG93476.1};
KW Protein biosynthesis {ECO:0000313|EMBL:AHG93476.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000019151}.
FT DOMAIN 1..171
FT /note="Tr-type G"
FT /evidence="ECO:0000259|PROSITE:PS51722"
SQ SEQUENCE 621 AA; 67513 MW; 38063930B2A02B0F CRC64;
MRLIGTAGHI DHGKSTLVQA LTGVHPSRLP EERARGMTID LGYAHLDHPD GHRLGVVDVP
GHEKLVKNMV AGATGFELAL WVVDARESVM PQSREHLHIL ELLGVRALMP VITKAAVATA
EQIERTERDV ASLVSDVALP VLASHVVDSV SGAGIAELKR AIFAATRDQP ADDDAPPYLA
IDRAFSVKGV GTVVTGTLVR GTLAEGDEVV VTSAPGTWRV RALTNHHARV ARIGAGHRVG
VNLAGLHADD VRRGDVLVSP AHPYRARRVN ARLRWTPDAP RAWKHGAPLL FHAGCLEVEC
RLWGTEEADG ASWAQLELSR EACFFPGQRF ILRGGTPLAT VGGGEILDLA PDRPRRVTMA
ERAAYVARAR GDECLSVYHA AAGATVLDLA ALARRWMVAE DTLRRDVARS ASLRLLTPDG
PLAWSTSAAT AARERLRRWL DAEPRDEHAV PYERVARELR LPPAHVQAVM RALLAADAES
ASRLRLDGAA AVVHPGRVEL APEDQRLADA LLARLRREWL KPSTVDAYRE LLPAPRGALD
RVVARLCEAG RLVRVSRDLV LHADAARALR NAPAHYGLDA VRAAEFGQAL GLTRKHGIPY
LEFLNREGIM RRAGDVHHRV R
//
