ID W0Z7C2_9MICO Unreviewed; 495 AA.
AC W0Z7C2;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 24-JAN-2024, entry version 31.
DE RecName: Full=beta-N-acetylhexosaminidase {ECO:0000256|ARBA:ARBA00012663};
DE EC=3.2.1.52 {ECO:0000256|ARBA:ARBA00012663};
GN ORFNames=MIC448_1250005 {ECO:0000313|EMBL:CDJ99216.1};
OS Microbacterium sp. C448.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Microbacteriaceae;
OC Microbacterium.
OX NCBI_TaxID=1177594 {ECO:0000313|EMBL:CDJ99216.1, ECO:0000313|Proteomes:UP000028883};
RN [1] {ECO:0000313|EMBL:CDJ99216.1, ECO:0000313|Proteomes:UP000028883}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C448 {ECO:0000313|EMBL:CDJ99216.1,
RC ECO:0000313|Proteomes:UP000028883};
RX PubMed=24526651; DOI=10.1128/genomeA.01113-13;
RA Martin-Laurent F., Marti R., Waglechner N., Wright G.D., Topp E.;
RT "Draft Genome Sequence of the Sulfonamide Antibiotic-Degrading
RT Microbacterium sp. Strain C448.";
RL Genome Announc. Announc.2:e01113-e01113(2014).
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 20 family.
CC {ECO:0000256|ARBA:ARBA00006285}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CDJ99216.1}.
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DR EMBL; CBVQ010000030; CDJ99216.1; -; Genomic_DNA.
DR RefSeq; WP_036299229.1; NZ_HG779705.1.
DR AlphaFoldDB; W0Z7C2; -.
DR STRING; 1177594.MIC448_1250005; -.
DR eggNOG; COG3525; Bacteria.
DR HOGENOM; CLU_007082_5_1_11; -.
DR OrthoDB; 9763537at2; -.
DR Proteomes; UP000028883; Unassembled WGS sequence.
DR GO; GO:0004563; F:beta-N-acetylhexosaminidase activity; IEA:UniProtKB-EC.
DR GO; GO:0102148; F:N-acetyl-beta-D-galactosaminidase activity; IEA:UniProtKB-EC.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR CDD; cd06568; GH20_SpHex_like; 1.
DR Gene3D; 3.30.379.10; Chitobiase/beta-hexosaminidase domain 2-like; 1.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR InterPro; IPR025705; Beta_hexosaminidase_sua/sub.
DR InterPro; IPR015883; Glyco_hydro_20_cat.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR InterPro; IPR029018; Hex-like_dom2.
DR InterPro; IPR015882; HEX_bac_N.
DR PANTHER; PTHR22600; BETA-HEXOSAMINIDASE; 1.
DR PANTHER; PTHR22600:SF21; BETA-HEXOSAMINIDASE A; 1.
DR Pfam; PF00728; Glyco_hydro_20; 1.
DR Pfam; PF02838; Glyco_hydro_20b; 1.
DR PRINTS; PR00738; GLHYDRLASE20.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF55545; beta-N-acetylhexosaminidase-like domain; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:CDJ99216.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000028883}.
FT DOMAIN 2..126
FT /note="Beta-hexosaminidase bacterial type N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02838"
FT DOMAIN 130..462
FT /note="Glycoside hydrolase family 20 catalytic"
FT /evidence="ECO:0000259|Pfam:PF00728"
FT ACT_SITE 304
FT /note="Proton donor"
FT /evidence="ECO:0000256|PIRSR:PIRSR625705-1"
SQ SEQUENCE 495 AA; 53164 MW; A25E95F370A81833 CRC64;
MIPYPARVEP SDGALSLAGG LVVLADPGAS HEARELARSI TVRTGLTSTV QTTDASAPHP
GAIRLRLDPN VGLTAEAYTL RTDASDAEIV AATTTGLFYG AQTLVQAIEA GTDGGTWHLP
HLTIEDTPRF AYRGMMLDVA RHFFSVEDVC AVIDRAASLK LNHLHLHLSD DQGWRLQIDT
WPRLTGPEAS ASFYSKADYR RIVEYAETRH MTVVPEIDMP GHTHAVGIAY PELVEAPVIS
DALRAQVAEL GQQLPESGVP FTGWAVGFSS LRIGDETVDR FVHDVVRELA EVTPGRYLHI
GGDEALGTAP ADFAAFVSRA AHVVREVGKI PITWQEAGAV AELPAGTVGQ YWGFVAPQDG
HDDLARAFVR NGGRVILSPA DAAYLDMKPD AESALGLTWA NGPTSLRRAY DWEPLAVVEG
LTEHDILGVE AALWTETVET LADIDALVFP RIAAAAEIAW SNPPAMSAAR TWESFRERVD
ALAPLWLAAG IGGAR
//
