ID   W0Z7H1_9MICO            Unreviewed;       571 AA.
AC   W0Z7H1;
DT   19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT   19-MAR-2014, sequence version 1.
DT   24-JAN-2024, entry version 35.
DE   SubName: Full=Dihydroxyacid dehydratase/phosphogluconate dehydratase {ECO:0000313|EMBL:CDK00037.1};
GN   ORFNames=MIC448_2040008 {ECO:0000313|EMBL:CDK00037.1};
OS   Microbacterium sp. C448.
OC   Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Microbacteriaceae;
OC   Microbacterium.
OX   NCBI_TaxID=1177594 {ECO:0000313|EMBL:CDK00037.1, ECO:0000313|Proteomes:UP000028883};
RN   [1] {ECO:0000313|EMBL:CDK00037.1, ECO:0000313|Proteomes:UP000028883}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=C448 {ECO:0000313|EMBL:CDK00037.1,
RC   ECO:0000313|Proteomes:UP000028883};
RX   PubMed=24526651; DOI=10.1128/genomeA.01113-13;
RA   Martin-Laurent F., Marti R., Waglechner N., Wright G.D., Topp E.;
RT   "Draft Genome Sequence of the Sulfonamide Antibiotic-Degrading
RT   Microbacterium sp. Strain C448.";
RL   Genome Announc. Announc.2:e01113-e01113(2014).
CC   -!- SIMILARITY: Belongs to the IlvD/Edd family.
CC       {ECO:0000256|ARBA:ARBA00006486}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:CDK00037.1}.
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DR   EMBL; CBVQ010000118; CDK00037.1; -; Genomic_DNA.
DR   AlphaFoldDB; W0Z7H1; -.
DR   STRING; 1177594.MIC448_2040008; -.
DR   eggNOG; COG0129; Bacteria.
DR   HOGENOM; CLU_014271_4_2_11; -.
DR   OrthoDB; 4744252at2; -.
DR   Proteomes; UP000028883; Unassembled WGS sequence.
DR   GO; GO:0016836; F:hydro-lyase activity; IEA:InterPro.
DR   GO; GO:0019752; P:carboxylic acid metabolic process; IEA:UniProt.
DR   GO; GO:0044238; P:primary metabolic process; IEA:UniProt.
DR   Gene3D; 3.50.30.80; IlvD/EDD C-terminal domain-like; 1.
DR   InterPro; IPR042096; Dihydro-acid_dehy_C.
DR   InterPro; IPR000581; DiOHA_6PGluconate_deHydtase.
DR   InterPro; IPR020558; DiOHA_6PGluconate_deHydtase_CS.
DR   InterPro; IPR037237; IlvD/EDD_N.
DR   PANTHER; PTHR43661; D-XYLONATE DEHYDRATASE; 1.
DR   PANTHER; PTHR43661:SF3; D-XYLONATE DEHYDRATASE YAGF-RELATED; 1.
DR   Pfam; PF00920; ILVD_EDD; 1.
DR   SUPFAM; SSF143975; IlvD/EDD N-terminal domain-like; 1.
DR   SUPFAM; SSF52016; LeuD/IlvD-like; 1.
DR   PROSITE; PS00886; ILVD_EDD_1; 1.
PE   3: Inferred from homology;
KW   Lyase {ECO:0000256|ARBA:ARBA00023239};
KW   Reference proteome {ECO:0000313|Proteomes:UP000028883}.
SQ   SEQUENCE   571 AA;  59749 MW;  6CD7426C89885A2D CRC64;
     MPALRSNLPP TSALAIARRA HYTALGIPKA DWEKPKVAIV NTSSDLAACF SHLDEVAARL
     KHELRDAGLL PFEIRTTAPS DFVTSAGRAG RYILPSRDLI VDDIEAAVEG AKLDAMICLS
     SCDKTTPGHL MAAGRLDIPT IIIPCGYQHS GLAEGRTADI EEIFLHASKA AVTGESTDEL
     ELLAEDAILS PGVCAGLATA NSMHILAEAL GMAMPGSAPV RALSEPMWDT VSRSAHALAA
     LIENDIRPRQ IITEGSVRNA VRAMLAIGGS MNTIKHLQAI AIESGLDVDV WELFRQLGRE
     TPLLCSVRPN GPRLTEEFED AGGGATIIRE LLPLLDGTQL TVTGATVAEN SALAKPADGD
     VIRSIDDPFG TDPAISVLKG TLAPGGAVAK RPVPDPGPHT FRGPARIFGT REEAIAAISS
     GRLQEGDVAV IRGIGVTGAP GLGLTSAFIF ALHARGLAHS VALVTDGQFS GLVNQGMTVG
     EVSPEAASPG SPLGRVRDDD LIEIDVKRGT VDLLVDADEL AARPDYVPPV DRDTGHGYLD
     QYEALVQPLS CGAVLCARPC STNPSPVKES A
//