ID   W0ZC03_9MICO            Unreviewed;       374 AA.
AC   W0ZC03;
DT   19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT   19-MAR-2014, sequence version 1.
DT   24-JAN-2024, entry version 27.
DE   SubName: Full=Uncharacterized oxidoreductase MSMEG_1603/MSMEI_1564 {ECO:0000313|EMBL:CDK00333.1};
DE            EC=1.-.-.- {ECO:0000313|EMBL:CDK00333.1};
GN   ORFNames=MIC448_2380008 {ECO:0000313|EMBL:CDK00333.1};
OS   Microbacterium sp. C448.
OC   Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Microbacteriaceae;
OC   Microbacterium.
OX   NCBI_TaxID=1177594 {ECO:0000313|EMBL:CDK00333.1, ECO:0000313|Proteomes:UP000028883};
RN   [1] {ECO:0000313|EMBL:CDK00333.1, ECO:0000313|Proteomes:UP000028883}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=C448 {ECO:0000313|EMBL:CDK00333.1,
RC   ECO:0000313|Proteomes:UP000028883};
RX   PubMed=24526651; DOI=10.1128/genomeA.01113-13;
RA   Martin-Laurent F., Marti R., Waglechner N., Wright G.D., Topp E.;
RT   "Draft Genome Sequence of the Sulfonamide Antibiotic-Degrading
RT   Microbacterium sp. Strain C448.";
RL   Genome Announc. Announc.2:e01113-e01113(2014).
CC   -!- SIMILARITY: Belongs to the IMPDH/GMPR family.
CC       {ECO:0000256|ARBA:ARBA00005502}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:CDK00333.1}.
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DR   EMBL; CBVQ010000155; CDK00333.1; -; Genomic_DNA.
DR   AlphaFoldDB; W0ZC03; -.
DR   STRING; 1177594.MIC448_2380008; -.
DR   eggNOG; COG0516; Bacteria.
DR   HOGENOM; CLU_064068_0_0_11; -.
DR   Proteomes; UP000028883; Unassembled WGS sequence.
DR   GO; GO:0003938; F:IMP dehydrogenase activity; IEA:InterPro.
DR   GO; GO:0006164; P:purine nucleotide biosynthetic process; IEA:InterPro.
DR   CDD; cd00381; IMPDH; 1.
DR   Gene3D; 3.20.20.70; Aldolase class I; 1.
DR   InterPro; IPR013785; Aldolase_TIM.
DR   InterPro; IPR005990; IMP_DH.
DR   InterPro; IPR005992; IMP_DH-rel2.
DR   InterPro; IPR001093; IMP_DH_GMPRt.
DR   NCBIfam; TIGR01304; IMP_DH_rel_2; 1.
DR   PANTHER; PTHR11911:SF111; INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE; 1.
DR   PANTHER; PTHR11911; INOSINE-5-MONOPHOSPHATE DEHYDROGENASE RELATED; 1.
DR   Pfam; PF00478; IMPDH; 1.
DR   SMART; SM01240; IMPDH; 1.
DR   SUPFAM; SSF51412; Inosine monophosphate dehydrogenase (IMPDH); 1.
PE   3: Inferred from homology;
KW   Oxidoreductase {ECO:0000313|EMBL:CDK00333.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000028883}.
FT   DOMAIN          16..300
FT                   /note="IMP dehydrogenase/GMP reductase"
FT                   /evidence="ECO:0000259|Pfam:PF00478"
SQ   SEQUENCE   374 AA;  39311 MW;  E493F0B048655AAF CRC64;
     MSMEIELGRA KRARRAYTFD DIAVVPSRRT RNPEDVSTAW SIDAFQFDIP VLGAPMDSVV
     SPKTAIMLGQ LGGLGVLDLE GLWTRYEDPE PLLAEIAGRE DGDATLRMQE LYSEPIKPEL
     VTARLAEIRA AGVTVAGALT PQRTQELYET VVAAGVDIFV IRGTTVSAEH VSSVSAPLNL
     KKFIYDLDVP VIVGGAATYT AALHLMRTGA AGVLVGFGGG AASTTRVTLG IHAPMATAVA
     DVTGARRDYL DESGGRYVHV IADGGVGTSG DIVKALAMGA DAVMLGVALA RATDAPGQGF
     HWGPEAHHPK LPRGHRVRVD QVASLEGILY GPAPVADGTA NLIGALRKSM ATTGYSDLKE
     FQRVEVVVAP YSAG
//