ID   W1EV72_ECOLX            Unreviewed;       292 AA.
AC   W1EV72;
DT   19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT   19-MAR-2014, sequence version 1.
DT   27-MAR-2024, entry version 33.
DE   SubName: Full=Sensor kinase CitA, DpiB {ECO:0000313|EMBL:CDL26059.1};
DE            EC=2.7.3.- {ECO:0000313|EMBL:CDL26059.1};
OS   Escherichia coli ISC7.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=1432555 {ECO:0000313|EMBL:CDL26059.1, ECO:0000313|Proteomes:UP000019199};
RN   [1] {ECO:0000313|EMBL:CDL26059.1, ECO:0000313|Proteomes:UP000019199}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ISC7 {ECO:0000313|EMBL:CDL26059.1,
RC   ECO:0000313|Proteomes:UP000019199};
RA   Barisic I., Mitteregger D., Hirschl A.M., Noehammer C., Wiesinger-Mayr H.;
RT   "Antibiotic resistance diversity of beta-lactamase producers in the General
RT   Hospital Vienna.";
RL   Submitted (OCT-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:CDL26059.1}.
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DR   EMBL; CBWN010000050; CDL26059.1; -; Genomic_DNA.
DR   AlphaFoldDB; W1EV72; -.
DR   Proteomes; UP000019199; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0004673; F:protein histidine kinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR   CDD; cd00130; PAS; 1.
DR   CDD; cd18773; PDC1_HK_sensor; 1.
DR   Gene3D; 3.30.450.20; PAS domain; 2.
DR   InterPro; IPR000014; PAS.
DR   InterPro; IPR035965; PAS-like_dom_sf.
DR   InterPro; IPR013767; PAS_fold.
DR   InterPro; IPR033463; sCache_3.
DR   InterPro; IPR029151; Sensor-like_sf.
DR   Pfam; PF00989; PAS; 1.
DR   Pfam; PF17203; sCache_3_2; 1.
DR   SMART; SM00091; PAS; 1.
DR   SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR   SUPFAM; SSF103190; Sensory domain-like; 1.
PE   4: Predicted;
KW   Kinase {ECO:0000313|EMBL:CDL26059.1}; Membrane {ECO:0000256|SAM:Phobius};
KW   Transferase {ECO:0000313|EMBL:CDL26059.1};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        20..41
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        179..202
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          222..289
FT                   /note="PAS"
FT                   /evidence="ECO:0000259|SMART:SM00091"
SQ   SEQUENCE   292 AA;  32918 MW;  6B9A24997AC20DEF CRC64;
     MLQLNENKQF AFFQRLAFPL RIFLLILVFS IFVIAALAQY FTASFEDYLT LHVRDMAMNQ
     AKIIASNDSV ISAVKTRDYK RLATIANKLQ RDTDFDYVVI GDRHSIRLYH PNPEKIGYPM
     QFTKQGALEK GESYFITGKG SMGMAMRAKT PIFDDDGKVI GVVSIGYLVS KIDSWRAEFL
     LPMAGVFVVL LGILMLLSWF LAAHIRRQMM GMEPKQIARV VRQQEALFSS VYEGLIAVDP
     HGYITAINRN ARKMLGLSSP GRQWLGKPIA EVVRPADFFT EQIDEKTSGC GG
//