ID W1INX8_9GAMM Unreviewed; 2267 AA.
AC W1INX8;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 24-JAN-2024, entry version 51.
DE SubName: Full=Non-ribosomal peptide synthetase modules and related protein {ECO:0000313|EMBL:CDL80144.1};
GN ORFNames=XCR1_1390016 {ECO:0000313|EMBL:CDL80144.1};
OS Xenorhabdus cabanillasii JM26.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Morganellaceae; Xenorhabdus.
OX NCBI_TaxID=1427517 {ECO:0000313|EMBL:CDL80144.1, ECO:0000313|Proteomes:UP000019197};
RN [1] {ECO:0000313|EMBL:CDL80144.1, ECO:0000313|Proteomes:UP000019197}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JM26 {ECO:0000313|EMBL:CDL80144.1,
RC ECO:0000313|Proteomes:UP000019197};
RA Gualtieri M., Ogier J.C., Pages S., Givaudan A., Gaudriault S.;
RT "Draft genome sequence and annotation of the entomopathogenic bacterium,
RT Xenorhabdus cabanillasi strain JM26.";
RL Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CDL80144.1}.
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DR EMBL; CBXE010000045; CDL80144.1; -; Genomic_DNA.
DR RefSeq; WP_051502272.1; NZ_NJGH01000012.1.
DR OrthoDB; 6437256at2; -.
DR Proteomes; UP000019197; Unassembled WGS sequence.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR CDD; cd05930; A_NRPS; 1.
DR CDD; cd19544; E-C_NRPS; 1.
DR Gene3D; 3.30.300.30; -; 2.
DR Gene3D; 3.40.50.980; -; 2.
DR Gene3D; 1.10.1200.10; ACP-like; 2.
DR Gene3D; 3.30.559.10; Chloramphenicol acetyltransferase-like domain; 2.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR Gene3D; 3.30.559.30; Nonribosomal peptide synthetase, condensation domain; 2.
DR InterPro; IPR010071; AA_adenyl_domain.
DR InterPro; IPR036736; ACP-like_sf.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR InterPro; IPR023213; CAT-like_dom_sf.
DR InterPro; IPR001242; Condensatn.
DR InterPro; IPR009081; PP-bd_ACP.
DR NCBIfam; TIGR01733; AA-adenyl-dom; 2.
DR PANTHER; PTHR45527:SF1; FATTY ACID SYNTHASE; 1.
DR PANTHER; PTHR45527; NONRIBOSOMAL PEPTIDE SYNTHETASE; 1.
DR Pfam; PF00501; AMP-binding; 2.
DR Pfam; PF13193; AMP-binding_C; 2.
DR Pfam; PF00668; Condensation; 1.
DR Pfam; PF00550; PP-binding; 2.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 2.
DR SUPFAM; SSF47336; ACP-like; 2.
DR SUPFAM; SSF52777; CoA-dependent acyltransferases; 4.
DR PROSITE; PS00455; AMP_BINDING; 2.
DR PROSITE; PS50075; CARRIER; 2.
PE 4: Predicted;
FT DOMAIN 574..648
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT DOMAIN 1734..1809
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT REGION 896..915
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 900..915
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2267 AA; 249084 MW; CB141BEBE0FD7700 CRC64;
MSEKSLLSGQ HEYAVHQLFE QQVMKTPDAI AVRFGAQTLS YDQLNRRANR LAHYLRRHHL
GRHCGQTETP GNEGDETPDN AISAVGICLD RGIDTIVAVC GVLKAGAAYV PVDLSYPAER
QAYILHDSNV SVVITSGDII SSLPSSIRCI DLDQQNLPHQ DKADFTDEEN LTATCTPDSL
AYLIYTSGST GNPKGVRMPH KALVNLLVWQ NKKQSDELGG GEVSKKTLQF SPLSFDVSFQ
EIFSTLSSGG ELVLIPNLLR LDPLALLSFL SEQRIERLFL PYVALNSLAS AAVSEDCYPA
SLIDVITAGE QLIITAAIRQ FFKTLPQCRL HNHYGPSETH VVTAYTLEGS VEHWSALPPV
GTPIDNAEIY LLDDQNQIIV DGSAGELCIA GTPLAYGYHQ RPEETAAKFV DIALDGETSK
RMYRTGDLAQ WGPNGLLNVL GRIDFQVKIR GHRVEPGEIE ALLMTHPAVR DAVVVAQGGY
VQKGSIEEIA ETEEIAEKRL VGFVIVSERA LQRQAQDGVK ESILRFIRDA VPDYMCPAAI
VIVDHFPLSA SGKIDRKAFP TVSPDALMQQ EIEPPKTALE HTVAEVWSEL LGVKKVGRNS
HFLSLGGHSL LAVNVMLALR RRGFRVDAQT LYQYPVLSEL AEQLQHSSQA EFQQERAAEM
IHDGMENAFP WAPLSQAEMA ALSAVIPGGA ANIQDIYPLG SLQQGILYHS LADSGGDPYV
LWQVTRFSNS LLLHAYLDAL RHTIARHDAF RVSIHYEGLS QPVQVVCREA ELTVEELPLT
AEQDDPLTAL KQYCDPAMQR FDMTKAPLQR CLYCYDSRQD EWVLLHLLHH ITVDHATIEM
MQLEIEAQLL SQPLAEVSPL SFRQTMVTLF NTGNSAEQQA FFAGLLQDYE PASAPLGAGS
DSDANAQEND AQESNALESK ALRGNDSIME AWRPLPQPLN DQIRQQAKTH GVSAAAIFHL
AWAKVLSGLT GQDDVVFGTV LLGRLFAGEA SINVMGQFIN TLPIRMRLGN LPVLECLWET
QDTLTQLVRH EQASLALAQK SVQTAAGTSL FTSLLNYRHS EVRNVPSADP FQAVNPSAVE
GIRYSGVMER TNYPVSVNVD DFASDFVINT QVGEGFDPEL IGDYLQTALS EIVTALTSAP
QRRIGRISAL PAQERHKLLY QWNQTGADFP RQACLHTLIE EQVKRTPDAI AVVFDDTAFD
GAAFGNTGSA GNAPCHILNY RQLNQKANQL ARYLRTELGV GPDALVGVCV ERSIEMVVAL
LAVLKAGGAY VPLDPNYPAE RLDYMLHDAA PRAVLSHQGV SDTVRTLLAD YATETGAAVI
DLNEDISKWS TQDTDDLSTE AMGLTSSHLA YVIYTSGSTG RPKGVMNEHR AVVNRLVWMQ
KAYALGEDDV VLQKTPFSFD VSVWEFFWPL MFGARLSVAK PEGHKDPLYL STLIREQKIT
TLHFVPSMLS VFLEHASLGI HHCMKRVFCS GEALPVRSVQ RFHEQFAHVE LHNLYGPTEA
AIDVSAWDCS LQAMGQPTGG IAERNIGKNI IPIGKPIDNI QLYILDSYGQ PTPVGTVGEL
HIAGVGVARG YLNQPELTAE KFIKDPFGTA PAGVMYRTGD LARYLPNGDI EYLGRNDFQV
KLRGFRIELG EVETALSSHA SVKECLVLVR EDTPGDARLV AYVIPASVTD LADKQTETLN
QTLKAHLQTC LPAFMVPSHI VWLATFPLTA NGKLDRKALP LPAASMIPSE VAEPPRSGTE
TRLAQLWAEL LNINPPGRQT HFFEAGGHSL LAVALMMRIH QEFGVSVLLS SLVSHLDLAS
QAVLIDAELN NTAELSKMEA QAPSGSVAPA KSVSEGLIRA LPAQKAIYKA LKLNPQDLSN
NSFIVLSFEA EPDLKQLRGV LQSVLVRHAS LSAKFILLDD ELYLQPAKRF VFRLEKRQSL
GLLEEDLRDF VRPFSLEDGM NVRSRWVAAE LNPVLLLDFS HACIDGSGLM QICSELATGS
AASHIIDSES HSGINSGISL ATYADLFYSS EFAALKQLHG NFWREKLQDW QPPVGIEGAQ
SVTGSWLVSL NAEHKAQVEV LTARLKISVP EFFMTIFLRF KAHLESRFNY FYSSNPFSNA
PLTSSEQLTS MIFHGRDRPE QQTVVAPLMT VLPVRVTLQG DAGGSAMQDF DIVSNAIREA
CRHYLFDAEE LSVLYPALSK QALLPTTFFG YFQKEGFDGC IAGTACRQLE TPNISVGQSH
WNLTCEVAEH AAGFDIHLEA LSFNVVNDTE NWETLFSSIL QSGLNAG
//
