ID W1ISD5_9GAMM Unreviewed; 649 AA.
AC W1ISD5;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE SubName: Full=Putative Tyrosine decarboxylase {ECO:0000313|EMBL:CDL80526.1};
DE EC=4.1.1.25 {ECO:0000313|EMBL:CDL80526.1};
GN ORFNames=XSR1_10012 {ECO:0000313|EMBL:CDL80526.1};
OS Xenorhabdus szentirmaii DSM 16338.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Morganellaceae; Xenorhabdus.
OX NCBI_TaxID=1427518 {ECO:0000313|EMBL:CDL80526.1, ECO:0000313|Proteomes:UP000019202};
RN [1] {ECO:0000313|EMBL:CDL80526.1, ECO:0000313|Proteomes:UP000019202}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 16338 {ECO:0000313|EMBL:CDL80526.1,
RC ECO:0000313|Proteomes:UP000019202};
RA Gualtieri M., Ogier J.C., Pages S., Givaudan A., Gaudriault S.;
RT "Draft genome sequence and annotation of the entomopathogenic bacteria,
RT Xenorhabdus cabanillasi strain JM26 and Xenorhabdus szentirmai strain DSM
RT 16338.";
RL Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC Evidence={ECO:0000256|ARBA:ARBA00001933,
CC ECO:0000256|PIRSR:PIRSR602129-50};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CDL80526.1}.
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DR EMBL; CBXF010000001; CDL80526.1; -; Genomic_DNA.
DR RefSeq; WP_038233462.1; NZ_NIBV01000002.1.
DR AlphaFoldDB; W1ISD5; -.
DR STRING; 1427518.XSR1_10012; -.
DR OrthoDB; 9803665at2; -.
DR Proteomes; UP000019202; Unassembled WGS sequence.
DR GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR GO; GO:0004837; F:tyrosine decarboxylase activity; IEA:UniProtKB-EC.
DR GO; GO:0019752; P:carboxylic acid metabolic process; IEA:InterPro.
DR Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR InterPro; IPR002129; PyrdxlP-dep_de-COase.
DR InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR InterPro; IPR021115; Pyridoxal-P_BS.
DR InterPro; IPR049373; TyrDC_C.
DR PANTHER; PTHR42735; -; 1.
DR PANTHER; PTHR42735:SF4; TYROSINE DECARBOXYLASE; 1.
DR Pfam; PF00282; Pyridoxal_deC; 1.
DR Pfam; PF21391; tyr_de_CO2_C; 1.
DR SUPFAM; SSF53383; PLP-dependent transferases; 1.
DR PROSITE; PS00392; DDC_GAD_HDC_YDC; 1.
PE 4: Predicted;
KW Lyase {ECO:0000256|ARBA:ARBA00023239, ECO:0000313|EMBL:CDL80526.1};
KW Pyridoxal phosphate {ECO:0000256|PIRSR:PIRSR602129-50};
KW Reference proteome {ECO:0000313|Proteomes:UP000019202}.
FT DOMAIN 487..626
FT /note="L-tyrosine decarboxylase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF21391"
FT MOD_RES 397
FT /note="N6-(pyridoxal phosphate)lysine"
FT /evidence="ECO:0000256|PIRSR:PIRSR602129-50"
SQ SEQUENCE 649 AA; 73585 MW; 67746C7D6AB54EC5 CRC64;
MTKSLRPNLN IDALFLGPKS ENAVFFREMM DYAISEHIHW RSGFHPSDAT FITSLDRHEH
DYRETLYQTE GILNQLSAKL KNTSVPFFSP RYLGHINSDT LMVSNLAYVM AMIYNQNNCT
YEVSPTTTEL ELESGLDLCR MFGYDPEKSW GHITSGGTVA NYEGLWVARN LKTLPFAIYQ
HPKTKALLSH KSPQQLKNMP TAEILDLITE IQKIGVFEEI RDMTCRGIGV KPEILGKLLV
PQSKHYSWTK AADIFGIGQE NIISLPVNEH YQTDVAKMRE ITFQLIEQGE PILAMIAVVG
TTEVGAIDRI DEVVALRQEC EKRYGESFYI HVDAAYAGYA CSMLLNEQGE FLEYDTLHSH
HRSIGIMPEE ISWPKPEVYE SFKALKHVDS ITVDPHKVGF IQYSAGAICM KDKRILGLIS
SKAAYVFAQD ENQKEATGIN RGILGSAIME GSKAGATAAA LWAAHRLLPL NISGYGKVIA
AGIVTAHKLL SKLSTLPPIV VGKHRFEVHT MLSPDFHMIN FTFKEIGNES LNNHNALNKR
LYELCSYSTG RAYTNDFLTS STALDYKEYG DTPWHYAEKC GFSREEWEKV HRIYVLRAAI
MTYCLRNEEH FQEFWQQLNA IFIKKLNQLV DEEEKKSRLI SGLYTPFIS
//
