ID W1J0J9_9GAMM Unreviewed; 2305 AA.
AC W1J0J9;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 24-JAN-2024, entry version 39.
DE SubName: Full=Non-ribosomal peptide synthetase {ECO:0000313|EMBL:CDL84257.1};
GN ORFNames=XSR1_420022 {ECO:0000313|EMBL:CDL84257.1};
OS Xenorhabdus szentirmaii DSM 16338.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Morganellaceae; Xenorhabdus.
OX NCBI_TaxID=1427518 {ECO:0000313|EMBL:CDL84257.1, ECO:0000313|Proteomes:UP000019202};
RN [1] {ECO:0000313|EMBL:CDL84257.1, ECO:0000313|Proteomes:UP000019202}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 16338 {ECO:0000313|EMBL:CDL84257.1,
RC ECO:0000313|Proteomes:UP000019202};
RA Gualtieri M., Ogier J.C., Pages S., Givaudan A., Gaudriault S.;
RT "Draft genome sequence and annotation of the entomopathogenic bacteria,
RT Xenorhabdus cabanillasi strain JM26 and Xenorhabdus szentirmai strain DSM
RT 16338.";
RL Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=pantetheine 4'-phosphate; Xref=ChEBI:CHEBI:47942;
CC Evidence={ECO:0000256|ARBA:ARBA00001957};
CC -!- PATHWAY: Siderophore biosynthesis. {ECO:0000256|ARBA:ARBA00004924}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CDL84257.1}.
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DR EMBL; CBXF010000102; CDL84257.1; -; Genomic_DNA.
DR STRING; 1427518.XSR1_420022; -.
DR Proteomes; UP000019202; Unassembled WGS sequence.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR GO; GO:0031177; F:phosphopantetheine binding; IEA:InterPro.
DR GO; GO:0043604; P:amide biosynthetic process; IEA:UniProt.
DR GO; GO:0019752; P:carboxylic acid metabolic process; IEA:UniProt.
DR GO; GO:1901566; P:organonitrogen compound biosynthetic process; IEA:UniProt.
DR GO; GO:0044550; P:secondary metabolite biosynthetic process; IEA:UniProt.
DR CDD; cd05930; A_NRPS; 1.
DR CDD; cd17643; A_NRPS_Cytc1-like; 1.
DR CDD; cd19544; E-C_NRPS; 1.
DR Gene3D; 3.30.300.30; -; 2.
DR Gene3D; 3.40.50.980; -; 4.
DR Gene3D; 1.10.1200.10; ACP-like; 2.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 2.
DR Gene3D; 3.30.559.10; Chloramphenicol acetyltransferase-like domain; 1.
DR Gene3D; 3.30.559.30; Nonribosomal peptide synthetase, condensation domain; 1.
DR InterPro; IPR010071; AA_adenyl_domain.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR036736; ACP-like_sf.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR023213; CAT-like_dom_sf.
DR InterPro; IPR001242; Condensatn.
DR InterPro; IPR020806; PKS_PP-bd.
DR InterPro; IPR020802; PKS_thioesterase.
DR InterPro; IPR009081; PP-bd_ACP.
DR InterPro; IPR006162; Ppantetheine_attach_site.
DR InterPro; IPR001031; Thioesterase.
DR NCBIfam; TIGR01733; AA-adenyl-dom; 2.
DR PANTHER; PTHR45527:SF1; FATTY ACID SYNTHASE; 1.
DR PANTHER; PTHR45527; NONRIBOSOMAL PEPTIDE SYNTHETASE; 1.
DR Pfam; PF00501; AMP-binding; 2.
DR Pfam; PF13193; AMP-binding_C; 2.
DR Pfam; PF00668; Condensation; 1.
DR Pfam; PF00550; PP-binding; 2.
DR Pfam; PF00975; Thioesterase; 2.
DR SMART; SM00823; PKS_PP; 2.
DR SMART; SM00824; PKS_TE; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 2.
DR SUPFAM; SSF47336; ACP-like; 2.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 2.
DR SUPFAM; SSF52777; CoA-dependent acyltransferases; 2.
DR PROSITE; PS00455; AMP_BINDING; 2.
DR PROSITE; PS50075; CARRIER; 2.
DR PROSITE; PS00012; PHOSPHOPANTETHEINE; 1.
PE 4: Predicted;
KW Phosphopantetheine {ECO:0000256|ARBA:ARBA00022450};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000019202}.
FT DOMAIN 572..646
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT DOMAIN 1664..1738
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
SQ SEQUENCE 2305 AA; 252578 MW; AFAA1F65ED34F9D3 CRC64;
MAQAVSGIDP SRVANYLVTA ISGLTEALAT ESRQSILSLP VLPAAERQQI LVDFNATRAD
FPQATLIHEL FEQQAARTPD AIAVVFKECT LSYGELNRRA NRLAHHLIAL GVQPDDRVAI
CVERSLEMMV GLLGILKAGA AYVPLDPAYP SERLAYILND AGPVALLTQS ALIETLGSSL
PAVLLDISVF GAYAESNPDT HTLGLTSRHL AYVIYTSGST GHPKGVMVEH RNIIASTYAR
QLTYPHFERL LLLSSIAFDS SLASIFGTLT RGGSLYLPEQ EITVNPTAIL QALHQNAISC
LLCVPSLALS LLQLANKEDM ASLRALIVAG ERCLPELHTR IEQLGLPIAL YNEYGPTEAT
VWASVYQVMS HDLFNVPIGR PIANTQIYIL DAQDQAVPIG VAGEIHIGGV GVTRGYLDRP
ALTAERFIPD PFSTEPDARL YKTGDIGRWL PDGNIEYLGR NDFQVKLRGF RIELGEIETR
LAQCPGVREA VVIAREDIPG EKRLVAYLQP QSGVELVPAE LRQQLAQQLA EYMIPSAFVM
LETFPLTPNG KLDRQALPAP DQSAVATRVY AAPEGTLETA LALIWQDLLG LESVSRHDHF
FELGGHSLMA VSLIERLRNA GWLLDVRNVF STPVLTEMAQ MIQAHQGKPA FVVPPNRITE
DCTTLTPDLL PLVTLSQAEI DTIVGTVPGG TANVQDIYPL APLQEGILFH HRLQEQGDAY
LLCSLVAFDT RERLDAFLSA LQRVINRHDI LRTAICWQGL TQPVQVVWRQ ASLPVNTFVP
TSKDNVLEGN VLAQLQAYTD PHQRRLNLNQ APLFSADIAH DPANHEWLLA LSFHHMISDH
MTLELIVSEI NLLLQERAEL LPVPLPYRNF IAQTLNVPAS VHEDYFRARL ADIDAPTAPF
GLLNVQGDGK DVAETYLKLD TTLARAIRSQ ARRLGINPGV LFHVAWAQVL AQTSGRDDVV
FGSVLLGRLQ GYAGADQVMG MFINTLPVRI SLAGISVLEV IQATYQDLMA LLEHEQAPLA
LAIRCSGVTP PMPLFSALLN YRHSHSGAAD AKVWNGMRML TAEERTNYPL TLSVDDLGED
FSLVTQSVSG IDPTRLANYL ITAISGLVEA LANDPQRLVL SLPILPAAER QQLLVDFNAP
QTDFPQEALI HELFEQQAML APDAIAVVCA GQSLSYGELN RRANRLAHHL LTLGVQPDDR
VAICVERSLE MVVGLLGILK AGAAYLPLDP AYPAERLAYM LSDAAPVALL TQSVLAETLD
SHLPTVVLDA RSPSALDGAP DSNPDSRARG ITSRHLAYVI YTSGSTGQPK GVMVEHANIL
RLLAATQDYF RFSHHDVWTL FHSFAFDFSV WELWGALAYG GRLVIVPAAC ARSPQAFYAL
LCDERVTVLN QTPSAFRQLI PAQDDTAHAL RCIIFGGEAL ELPLLAPWIA NNPISQTRLV
NMYGITEITV HATYRELTGD DISGGRGSLV GQPLPDLHAY LLDPHGQPVP LGVTGELYIG
GVGVARGYLN RPALTAERFI PDPFSTTPGS RLYKTGDLGR WLPDGNIEYL GRNDFQVKLR
GFRIELGEIE ARLAQCSEVR DAVVIAREDI PGDTRLVAYL LPQPGTELVP AALRQQLAQH
LADYMLPSAF VMLEAFPLTP NGKLDRKALP APEQSAIVVQ GYVPPQGEVE TMLAQIWQEL
LGLERVGRHD NFFESGGHSL LAVQLLNCIS EQGMEVSLAT LFSHPTLCDL ALAINDKSNK
PSSPFDANPV PLSPKGSLSP LFLVHETTGD PLVYSLLATL LPPERPVYGL QALGLHTLEK
PPTSIEELAA YHVQAIRRVQ PHGPYHLAGW SIGGVIVYEM ALQLISHGEE VKYLGMIDSY
NLSGLKIGTE SGHNIDANKS VNDTQKDINT IIEYLRDHID VIDKHDLDKL YDFNDMDKLL
TFCEEHQWLP TGITKADILL RIYTQRAILQ FGQKYIAPAS SLSIHLYTAD NLPAEYDSWR
GWRNIVGENS VLHSIGGTHN SIMQQPLLGQ LADLITEHLL PTTYTPNIVI QNGDKSIPPL
FCIPGAGANA SGFIGLALSL PPKLPVHALQ SRGLIDAHLP PYISVESSAH AYIQAIRQTQ
PHGPYHLLGH SFGGWIAFEI ALQLQAQGEQ VTDLILVDTS APDPQDSVPK AVGRIETLMK
LIDIYNMMLT QPLPFTSQDF ENQEPDEQIR TLFQALVNAG IFPGDANTSL LQGIVQVMQA
NLNTSYTPHT RYKGLVHLIN AKEGDIDETE AHEKMGRRHV TQLSTITAPG NHMTMLSSPQ
VNQLATLLWE KLDYVSTNFG GWFMK
//
