GenomeNet

Database: UniProt
Entry: W1J111_9GAMM
LinkDB: W1J111_9GAMM
Original site: W1J111_9GAMM 
ID   W1J111_9GAMM            Unreviewed;       235 AA.
AC   W1J111;
DT   19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT   19-MAR-2014, sequence version 1.
DT   27-SEP-2017, entry version 25.
DE   RecName: Full=DnaA regulatory inactivator Hda {ECO:0000256|HAMAP-Rule:MF_01158, ECO:0000256|SAAS:SAAS00634471};
GN   Name=hda {ECO:0000256|HAMAP-Rule:MF_01158,
GN   ECO:0000313|EMBL:CDL83556.1};
GN   ORFNames=XSR1_320030 {ECO:0000313|EMBL:CDL83556.1};
OS   Xenorhabdus szentirmaii DSM 16338.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Morganellaceae; Xenorhabdus.
OX   NCBI_TaxID=1427518 {ECO:0000313|EMBL:CDL83556.1, ECO:0000313|Proteomes:UP000019202};
RN   [1] {ECO:0000313|EMBL:CDL83556.1, ECO:0000313|Proteomes:UP000019202}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 16338 {ECO:0000313|EMBL:CDL83556.1,
RC   ECO:0000313|Proteomes:UP000019202};
RA   Gualtieri M., Ogier J.C., Pages S., Givaudan A., Gaudriault S.;
RT   "Draft genome sequence and annotation of the entomopathogenic
RT   bacteria, Xenorhabdus cabanillasi strain JM26 and Xenorhabdus
RT   szentirmai strain DSM 16338.";
RL   Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Mediates the interaction of DNA replication inititator
CC       protein DnaA with DNA polymerase subunit beta sliding clamp
CC       (dnaN). Stimulates hydrolysis of ATP-DnaA to ADP-DnaA, rendering
CC       DnaA inactive for reinititation, a process called regulatory
CC       inhibition of DnaA or RIDA. {ECO:0000256|HAMAP-Rule:MF_01158}.
CC   -!- SUBUNIT: The active form seems to be an ADP-bound monomer. Forms
CC       the RIDA complex (regulatory inactivation of DnaA) of ATP-DnaA,
CC       ADP-Hda and the DNA-loaded beta sliding clamp (dnaN).
CC       {ECO:0000256|HAMAP-Rule:MF_01158}.
CC   -!- SIMILARITY: Belongs to the DnaA family. HdA subfamily.
CC       {ECO:0000256|HAMAP-Rule:MF_01158, ECO:0000256|SAAS:SAAS00548763}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:CDL83556.1}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution-NoDerivs License
CC   -----------------------------------------------------------------------
DR   EMBL; CBXF010000091; CDL83556.1; -; Genomic_DNA.
DR   RefSeq; WP_038238982.1; NZ_CBXF010000091.1.
DR   EnsemblBacteria; CDL83556; CDL83556; XSR1_320030.
DR   Proteomes; UP000019202; Unassembled WGS sequence.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-UniRule.
DR   GO; GO:0032297; P:negative regulation of DNA-dependent DNA replication initiation; IEA:InterPro.
DR   HAMAP; MF_01158; Hda; 1.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR017788; Hda.
DR   InterPro; IPR022864; Hda_Enterobact.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   PRINTS; PR00051; DNAA.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR03420; DnaA_homol_Hda; 1.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000019202};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_01158,
KW   ECO:0000256|SAAS:SAAS00634466};
KW   DNA replication inhibitor {ECO:0000256|HAMAP-Rule:MF_01158,
KW   ECO:0000256|SAAS:SAAS00634468};
KW   Reference proteome {ECO:0000313|Proteomes:UP000019202}.
FT   DOMAIN       18    213       Bac_DnaA. {ECO:0000259|Pfam:PF00308}.
SQ   SEQUENCE   235 AA;  26671 MW;  F78FC88F06ADF342 CRC64;
     MLLNTPSQLS LPLYLPDDET FASFFAGENT SLLAAIKLAI SQSHGSYIYF WSRDGGGKSH
     LLHAACTELS QQEEAVGYVP LDKRAYFVPE VLDGMEHLSL VCIDNIECIA GDQEWEMAIF
     NLYNRIVEIG QTCLLITGDR PPRQINLTLP DLASRLDWGQ IYKLQPLSDE EKIQALQLRA
     KLRGFELPED VGRFVLKRLD REMQTLFKTL DELDRASIVA QRKLTIPFVK DILEL
//
DBGET integrated database retrieval system