ID W1PDA7_AMBTC Unreviewed; 425 AA.
AC W1PDA7;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 27-MAR-2024, entry version 46.
DE RecName: Full=Origin of replication complex subunit 4 {ECO:0000256|PIRNR:PIRNR007858};
GN ORFNames=AMTR_s00006p00149820 {ECO:0000313|EMBL:ERN05659.1};
OS Amborella trichopoda.
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Amborellales; Amborellaceae; Amborella.
OX NCBI_TaxID=13333 {ECO:0000313|EMBL:ERN05659.1, ECO:0000313|Proteomes:UP000017836};
RN [1] {ECO:0000313|Proteomes:UP000017836}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=24357323;
RG Amborella Genome Project;
RT "The Amborella genome and the evolution of flowering plants.";
RL Science 342:1241089-1241089(2013).
CC -!- FUNCTION: Component of the origin recognition complex (ORC) that binds
CC origins of replication. {ECO:0000256|PIRNR:PIRNR007858}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|PIRNR:PIRNR007858}.
CC -!- SIMILARITY: Belongs to the ORC4 family. {ECO:0000256|ARBA:ARBA00005334,
CC ECO:0000256|PIRNR:PIRNR007858}.
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DR EMBL; KI393980; ERN05659.1; -; Genomic_DNA.
DR RefSeq; XP_006843984.1; XM_006843921.2.
DR AlphaFoldDB; W1PDA7; -.
DR STRING; 13333.W1PDA7; -.
DR EnsemblPlants; ERN05659; ERN05659; AMTR_s00006p00149820.
DR GeneID; 18433842; -.
DR Gramene; ERN05659; ERN05659; AMTR_s00006p00149820.
DR KEGG; atr:18433842; -.
DR eggNOG; KOG2228; Eukaryota.
DR HOGENOM; CLU_007115_0_1_1; -.
DR OMA; ETKFRHH; -.
DR OrthoDB; 230201at2759; -.
DR Proteomes; UP000017836; Unassembled WGS sequence.
DR GO; GO:0005664; C:nuclear origin of replication recognition complex; IBA:GO_Central.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0003688; F:DNA replication origin binding; IBA:GO_Central.
DR GO; GO:0006270; P:DNA replication initiation; IBA:GO_Central.
DR GO; GO:0009744; P:response to sucrose; IEA:EnsemblPlants.
DR CDD; cd00009; AAA; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR041664; AAA_16.
DR InterPro; IPR016527; ORC4.
DR InterPro; IPR032705; ORC4_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR12087; ORIGIN RECOGNITION COMPLEX SUBUNIT 4; 1.
DR PANTHER; PTHR12087:SF0; ORIGIN RECOGNITION COMPLEX SUBUNIT 4; 1.
DR Pfam; PF13191; AAA_16; 1.
DR Pfam; PF14629; ORC4_C; 1.
DR PIRSF; PIRSF007858; ORC4; 1.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW DNA replication {ECO:0000256|ARBA:ARBA00022705,
KW ECO:0000256|PIRNR:PIRNR007858};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PIRNR:PIRNR007858};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PIRNR:PIRNR007858};
KW Reference proteome {ECO:0000313|Proteomes:UP000017836}.
FT DOMAIN 49..206
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
SQ SEQUENCE 425 AA; 47871 MW; 3799260DF9720F37 CRC64;
MSTGAAADAQ ALLRCRLSDP RFSLSPSPSP DSNYSKLKFI LSNSIFESCN NSVLLLGPRG
CGKTTVLELV LRKLQTDHPD RLSVVRLNGL LHSDDRCALK EIVRQLCTDH QLIFSKMASC
DDNSQFMLSM LRECALAHKA IIFVLDEFDL FTPGKQRLLY SLLDAMQSVQ SQAVVVGVSC
RLDADQLLEK RVRSRFSHRK LLFLPPSMED LQRLLRQILF LPTDSSFRHS DFAVKFNAKL
SVIFNGEGFI DILNSVVGVD NSVSHLLNFL FCAVCNMDSG SGFLSLGSFK SAMLSVQRQL
KLESLQDVSI LELYILVCMK RLEAKDCGSY NFNSIMKEYK GLQDASQTGA YYSRQVCLRA
FEHLLECELV GFTDNNRGQS LSIEFRAVVL LISSHELYQG LRSSRNCPDI LLQWFDRENP
KSHAY
//
