ID W1PFZ3_AMBTC Unreviewed; 340 AA.
AC W1PFZ3;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE RecName: Full=3-beta hydroxysteroid dehydrogenase/isomerase domain-containing protein {ECO:0000259|Pfam:PF01073};
GN ORFNames=AMTR_s00058p00164240 {ECO:0000313|EMBL:ERN06619.1};
OS Amborella trichopoda.
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Amborellales; Amborellaceae; Amborella.
OX NCBI_TaxID=13333 {ECO:0000313|EMBL:ERN06619.1, ECO:0000313|Proteomes:UP000017836};
RN [1] {ECO:0000313|Proteomes:UP000017836}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=24357323;
RG Amborella Genome Project;
RT "The Amborella genome and the evolution of flowering plants.";
RL Science 342:1241089-1241089(2013).
CC -!- SIMILARITY: Belongs to the 3-beta-HSD family.
CC {ECO:0000256|RuleBase:RU004475}.
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DR EMBL; KI393888; ERN06619.1; -; Genomic_DNA.
DR RefSeq; XP_006844944.1; XM_006844881.2.
DR AlphaFoldDB; W1PFZ3; -.
DR STRING; 13333.W1PFZ3; -.
DR EnsemblPlants; ERN06619; ERN06619; AMTR_s00058p00164240.
DR GeneID; 18434818; -.
DR Gramene; ERN06619; ERN06619; AMTR_s00058p00164240.
DR KEGG; atr:18434818; -.
DR eggNOG; KOG1502; Eukaryota.
DR HOGENOM; CLU_007383_9_1_1; -.
DR OMA; AMDYGAC; -.
DR OrthoDB; 1215685at2759; -.
DR Proteomes; UP000017836; Unassembled WGS sequence.
DR GO; GO:0003854; F:3-beta-hydroxy-delta5-steroid dehydrogenase activity; IEA:InterPro.
DR GO; GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IBA:GO_Central.
DR GO; GO:0006694; P:steroid biosynthetic process; IEA:InterPro.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR002225; 3Beta_OHSteriod_DH/Estase.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR10366:SF589; CINNAMOYL-COA REDUCTASE-LIKE SNL6; 1.
DR PANTHER; PTHR10366; NAD DEPENDENT EPIMERASE/DEHYDRATASE; 1.
DR Pfam; PF01073; 3Beta_HSD; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000256|RuleBase:RU004475};
KW Reference proteome {ECO:0000313|Proteomes:UP000017836}.
FT DOMAIN 52..166
FT /note="3-beta hydroxysteroid dehydrogenase/isomerase"
FT /evidence="ECO:0000259|Pfam:PF01073"
SQ SEQUENCE 340 AA; 37819 MW; 00DEA56CF5A731BE CRC64;
MRTPQVAPIQ LHPTIPISYY NTPVYLCSPK WPEKSNSRLF LPQSGNEKHV CVTGGGSFSL
ILVKELLSRG YTVRLTVHSE GEMETMEKIE DLWSVEKLSA KMSDIESLCD AFQGCGAVFH
TSSFIDPHGL SGYTERMASL ESKGAENVIK ACAKARVNKC ILTSSLLACI WQSPTTATTT
TTTTIDESFW SDEALCRENK LWLALGKTTA EQKAWRLAEE RKVKMVSILP GLIPPVSLHS
NLATSVAYLK GGRHMLERGL LATIEVTKVA KAHVHIYEKM DYKAKGRFLC FDKVINQNED
ILDLEKKFGM CGQLLGGTLP CEYYHPILTN SKLLQLIPSM
//
