ID W1PRR4_AMBTC Unreviewed; 355 AA.
AC W1PRR4;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 24-JAN-2024, entry version 36.
DE RecName: Full=tRNA-uridine aminocarboxypropyltransferase {ECO:0000256|ARBA:ARBA00012386};
DE EC=2.5.1.25 {ECO:0000256|ARBA:ARBA00012386};
GN ORFNames=AMTR_s00025p00248900 {ECO:0000313|EMBL:ERN12692.1};
OS Amborella trichopoda.
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Amborellales; Amborellaceae; Amborella.
OX NCBI_TaxID=13333 {ECO:0000313|EMBL:ERN12692.1, ECO:0000313|Proteomes:UP000017836};
RN [1] {ECO:0000313|Proteomes:UP000017836}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=24357323;
RG Amborella Genome Project;
RT "The Amborella genome and the evolution of flowering plants.";
RL Science 342:1241089-1241089(2013).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a uridine in tRNA + S-adenosyl-L-methionine = a 3-[(3S)-3-
CC amino-3-carboxypropyl]uridine in tRNA + H(+) + S-methyl-5'-
CC thioadenosine; Xref=Rhea:RHEA:62432, Rhea:RHEA-COMP:13339, Rhea:RHEA-
CC COMP:16092, ChEBI:CHEBI:15378, ChEBI:CHEBI:17509, ChEBI:CHEBI:59789,
CC ChEBI:CHEBI:65315, ChEBI:CHEBI:82930; EC=2.5.1.25;
CC Evidence={ECO:0000256|ARBA:ARBA00024168};
CC -!- SIMILARITY: Belongs to the TDD superfamily. DTWD2 family.
CC {ECO:0000256|ARBA:ARBA00034489}.
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DR EMBL; KI392614; ERN12692.1; -; Genomic_DNA.
DR RefSeq; XP_006851111.1; XM_006851048.1.
DR AlphaFoldDB; W1PRR4; -.
DR STRING; 13333.W1PRR4; -.
DR EnsemblPlants; ERN12692; ERN12692; AMTR_s00025p00248900.
DR GeneID; 18440913; -.
DR Gramene; ERN12692; ERN12692; AMTR_s00025p00248900.
DR KEGG; atr:18440913; -.
DR eggNOG; KOG4382; Eukaryota.
DR HOGENOM; CLU_781555_0_0_1; -.
DR OMA; CARARCE; -.
DR OrthoDB; 206884at2759; -.
DR Proteomes; UP000017836; Unassembled WGS sequence.
DR GO; GO:0016432; F:tRNA-uridine aminocarboxypropyltransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
DR InterPro; IPR005636; DTW.
DR InterPro; IPR039262; DTWD2/TAPT.
DR PANTHER; PTHR21392:SF0; TRNA-URIDINE AMINOCARBOXYPROPYLTRANSFERASE 2; 1.
DR PANTHER; PTHR21392; UNCHARACTERIZED; 1.
DR Pfam; PF03942; DTW; 2.
DR SMART; SM01144; DTW; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000017836};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW tRNA processing {ECO:0000256|ARBA:ARBA00022694}.
FT DOMAIN 29..341
FT /note="DTW"
FT /evidence="ECO:0000259|SMART:SM01144"
FT REGION 126..146
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 167..222
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 355 AA; 37961 MW; 0C44C4FF03C64FBF CRC64;
MLAQEKGGED CDLEPTLAGF EPEVESTCAR ARCEGPCARP LSVCVCAHLP PTRIKTLAHV
LVLQHPHETR HPLNTLSLLS ASLSNLSLVH GRVLRRGLSP LLDSNPPKTL FFFPSPSAKP
LTEWLASQGS SPYSDGGASA STLSPFSNNN GGSSDSCLYN NAGSSGSTQM SRPYSNEGFF
SSSPSPCPYR NGGASGSEQS YNPDNSAGPV SAQSDPHGNG ESTAWNRSSV LYNNGDSCGS
PLVLIFFDGT WKHAKEMMRA SLPFLLEFAE QVCFPFEIGL EGASVYSGEL VLRKEPFKGC
LSTMEAVARA LGMVEREGKT IEEKLLGILR AAVEFQASNL KDLMPRPKLC RKGGV
//
