ID W1PV14_AMBTC Unreviewed; 1058 AA.
AC W1PV14;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 27-MAR-2024, entry version 44.
DE RecName: Full=non-specific serine/threonine protein kinase {ECO:0000256|ARBA:ARBA00012513};
DE EC=2.7.11.1 {ECO:0000256|ARBA:ARBA00012513};
GN ORFNames=AMTR_s00022p00151480 {ECO:0000313|EMBL:ERN11551.1};
OS Amborella trichopoda.
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Amborellales; Amborellaceae; Amborella.
OX NCBI_TaxID=13333 {ECO:0000313|EMBL:ERN11551.1, ECO:0000313|Proteomes:UP000017836};
RN [1] {ECO:0000313|Proteomes:UP000017836}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=24357323;
RG Amborella Genome Project;
RT "The Amborella genome and the evolution of flowering plants.";
RL Science 342:1241089-1241089(2013).
CC -!- SIMILARITY: Belongs to the protein kinase superfamily. Ser/Thr protein
CC kinase family. {ECO:0000256|ARBA:ARBA00008684}.
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DR EMBL; KI392687; ERN11551.1; -; Genomic_DNA.
DR AlphaFoldDB; W1PV14; -.
DR EnsemblPlants; ERN11551; ERN11551; AMTR_s00022p00151480.
DR Gramene; ERN11551; ERN11551; AMTR_s00022p00151480.
DR eggNOG; ENOG502QPYS; Eukaryota.
DR HOGENOM; CLU_000288_22_0_1; -.
DR OrthoDB; 414932at2759; -.
DR Proteomes; UP000017836; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 4.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR013210; LRR_N_plant-typ.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR017441; Protein_kinase_ATP_BS.
DR InterPro; IPR001245; Ser-Thr/Tyr_kinase_cat_dom.
DR InterPro; IPR008271; Ser/Thr_kinase_AS.
DR PANTHER; PTHR27008; OS04G0122200 PROTEIN; 1.
DR PANTHER; PTHR27008:SF591; PROTEIN KINASE DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00560; LRR_1; 6.
DR Pfam; PF13855; LRR_8; 2.
DR Pfam; PF08263; LRRNT_2; 2.
DR Pfam; PF07714; PK_Tyr_Ser-Thr; 1.
DR SMART; SM00369; LRR_TYP; 12.
DR SMART; SM00220; S_TKc; 1.
DR SUPFAM; SSF52058; L domain-like; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR SUPFAM; SSF52047; RNI-like; 1.
DR PROSITE; PS00107; PROTEIN_KINASE_ATP; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR PROSITE; PS00108; PROTEIN_KINASE_ST; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU10141}; Kinase {ECO:0000256|ARBA:ARBA00022777};
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU10141}; Reference proteome {ECO:0000313|Proteomes:UP000017836};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Serine/threonine-protein kinase {ECO:0000256|ARBA:ARBA00022527};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..18
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 19..1058
FT /note="non-specific serine/threonine protein kinase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004807759"
FT TRANSMEM 706..727
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 760..1053
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT BINDING 788
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10141"
SQ SEQUENCE 1058 AA; 117217 MW; FA21DF9B32428D20 CRC64;
MKLPHLLPFL TLILFAFAFS MTLPLMSESH LSLLNNRTDQ QPLLSFKDHI TSDPYNVLGD
WNTRTNFCNW TGVSCSKSRQ RVTYLNLTHT GLQGTLTPHI GNLSFLRVLA LRNNSLQGSI
PPEIGRLSRL QVLRVSQNQL EGKIPPSISG CKKLQRLILS YNRLEGSIPE ELGILPNIKV
MYLGFNSLTG SIPPSLGNLS TLEEIHLSSN RLHGSIPKKL GLLQKLKLLH LHHNFVRGTI
PPSLGNLSSL ETIHLGNNLL HGSIPKEIGL LGRLALLTFH ANNLTGPIPS TFNISSLRGL
DLRSNGLSGQ LPTNMGFMLP NLENLNLGGN QLSGPIPTSL HNASKLNVIK LQHNQFNGPV
PTSLGHLSLL EVLFLHGNQL ENDPYSSYLS FIDYLTNCTI LNELQLGDNH ITGFLPNSIG
NFSNNLQIFS IGGCHIKGSI PMSISNLHNL RCLDLSRNSL SGNLPSDIGR LQKIDRLLLN
ENKLEGSIPP EFGQLESLLE LYLNDNMLSS PIPPSMNNLT KISHLYLGNN RLFGELPTEI
WRQGLLEVDL SGNSFSGLLP QELGSSSMLI TMNFSANRLF GNLPNSMGNL QALENLDLSL
NSFQGTIPRT FGEMRSLKYM DISSNKLSGE IPRSLGSLNY LLFLNLSFNG FEGPIPSKGV
FANITADSFI GNSRLCGPSK LKVPACPKNG TTPRSRSWTR SLAFEIPLGI ICAFVFSLLC
FVLVFFWRHE LRIAITDGVS QIKGPRWISY CELRHATNNF NHSNLLGAGS FGCVYKGFLS
DSSHVAIKVL DLQREGATKS FHAECTVMRK IRHRNLVKVI TACCNLDFKA LVLQFMPNGN
LERWLYPQDH ACCQLSFLQR LDIVINIADA LEYLHHNYSV PIVHRDLKPS NVLLDEDMIA
HVGDFGLARL IGEENFVTET STIGTIGYIA PEYGTGGSIT TGGDVYSFGV ILFETFTRKR
PIDSMFSNGL NLPKWVDQEY PDGMLQVVDG DLLMENISHN NGRNSRLQYS SSMHKCLSSV
MEVGLLCTKE RPNERINIRD ATLNLKDARS SYIAILRA
//
