ID   W1PWW0_AMBTC            Unreviewed;       927 AA.
AC   W1PWW0;
DT   19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT   19-MAR-2014, sequence version 1.
DT   27-MAR-2024, entry version 44.
DE   RecName: Full=RNA helicase {ECO:0000256|ARBA:ARBA00012552};
DE            EC=3.6.4.13 {ECO:0000256|ARBA:ARBA00012552};
GN   ORFNames=AMTR_s00025p00122870 {ECO:0000313|EMBL:ERN12399.1};
OS   Amborella trichopoda.
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Amborellales; Amborellaceae; Amborella.
OX   NCBI_TaxID=13333 {ECO:0000313|EMBL:ERN12399.1, ECO:0000313|Proteomes:UP000017836};
RN   [1] {ECO:0000313|Proteomes:UP000017836}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=24357323;
RG   Amborella Genome Project;
RT   "The Amborella genome and the evolution of flowering plants.";
RL   Science 342:1241089-1241089(2013).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.13;
CC         Evidence={ECO:0000256|ARBA:ARBA00001556};
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the DEAD box helicase family. DDX52/ROK1
CC       subfamily. {ECO:0000256|ARBA:ARBA00024355}.
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DR   EMBL; KI392614; ERN12399.1; -; Genomic_DNA.
DR   AlphaFoldDB; W1PWW0; -.
DR   STRING; 13333.W1PWW0; -.
DR   EnsemblPlants; ERN12399; ERN12399; AMTR_s00025p00122870.
DR   Gramene; ERN12399; ERN12399; AMTR_s00025p00122870.
DR   eggNOG; KOG0344; Eukaryota.
DR   HOGENOM; CLU_315317_0_0_1; -.
DR   Proteomes; UP000017836; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProt.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003724; F:RNA helicase activity; IEA:InterPro.
DR   GO; GO:0030490; P:maturation of SSU-rRNA; IEA:InterPro.
DR   CDD; cd17957; DEADc_DDX52; 1.
DR   CDD; cd16914; EcfT; 1.
DR   CDD; cd18787; SF2_C_DEAD; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR   InterPro; IPR003339; ABC/ECF_trnsptr_transmembrane.
DR   InterPro; IPR044764; DDX52/Rok1_DEADc.
DR   InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR   InterPro; IPR014013; Helic_SF1/SF2_ATP-bd_DinG/Rad3.
DR   InterPro; IPR014001; Helicase_ATP-bd.
DR   InterPro; IPR001650; Helicase_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR33514; PROTEIN ABCI12, CHLOROPLASTIC; 1.
DR   PANTHER; PTHR33514:SF13; PROTEIN ABCI12, CHLOROPLASTIC; 1.
DR   Pfam; PF02361; CbiQ; 1.
DR   Pfam; PF00270; DEAD; 1.
DR   Pfam; PF00271; Helicase_C; 1.
DR   SMART; SM00487; DEXDc; 1.
DR   SMART; SM00490; HELICc; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR   PROSITE; PS51193; HELICASE_ATP_BIND_2; 1.
DR   PROSITE; PS51194; HELICASE_CTER; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Reference proteome {ECO:0000313|Proteomes:UP000017836};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT   DOMAIN          514..796
FT                   /note="Helicase ATP-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS51193"
FT   DOMAIN          551..721
FT                   /note="Helicase ATP-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS51192"
FT   DOMAIN          732..893
FT                   /note="Helicase C-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS51194"
FT   REGION          469..490
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   927 AA;  103903 MW;  8D5E660732E58286 CRC64;
     MPWRPVAVPS TSCVCGLSPF LSSSNNRTIN CRGQFSNGVS FLCTGNQWRT PQLLKRKGGF
     FLVSCVDNRI NWGKEGVWPA KEMVGEKVLR LISGATSSPV AQFIEKPTTF LHSMDPRVKL
     VWLLALVVLP ASSNIVIRSS LVAFLSLLSI WALPDHIWKD QLGRVAFLSG ILFIMLALGS
     DGVPPLVQPR TPPPSMIGLP SLPKSLEGYS YSVMKLGPLQ LTRKGLSVAS ASACLSFTVF
     QSSSLCLTTT TPEQLALAWR WFMLPLSFIG VPVSEIILTL LLSLRFINLV FDEVRNIALG
     ILARGVHWRE LTIMETLDVF FTYVRQIFKN IFSHAEQISQ AMIVRGFRGN SNNHKIYLPN
     SSIGMLDVLL RRLMKSDKGG PIDEIIPLFS TELDAMEKSS LFAGCHFDRK RFAKDFAKFE
     LLKKAKNPPD MVVEASESVD GCTVGKKRKR KSASSEGFRV FKKPELEEIS KSNDKKSSAS
     EAEEKKERNR QIEQAALLRK KYGIHIAGQT VPSPLQNFEE LRLRYRCRLY LMRNLEKLGF
     SEPTPIQRQA IPVLLSGREC FACAPTGSGK TLAFVLPILM KLKRASRDGT RAIIICPTKE
     LAVQTTRECK KLAKGRKFFI RLMTRALSRC ADFEKMPCDI LVSTPLRLQK SLVKRKLDLS
     RVEYLVLDES DKLFELGFME QIDSVVKACS NPRIVRCLFS ATLPESVEEL ARTIMHDAIR
     IIVGRKNCAS DLIKQRLVFA GSEEGKLLAL RQTFAHSLNP PILVFVQSKE RAIELYKELE
     NLNVRAGVIH ADLTETEREN AVNGFREGKT WVLIATDVIA RGMDFKVVNC VINYDFPESA
     TTYIHRIGRT GRAARKGEAV TLYTEADVPL LRNIANLMVA SGCEVPSWIL ALPKLRGKKH
     RPQREHISTL PEDQAIIKSG KKRVPRK
//