ID W1Q4I9_ABIDE Unreviewed; 2994 AA.
AC W1Q4I9;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 24-JAN-2024, entry version 40.
DE SubName: Full=Signal peptide protein, YSIRK family {ECO:0000313|EMBL:ESK66122.1};
GN ORFNames=GCWU000182_000464 {ECO:0000313|EMBL:ESK66122.1};
OS Abiotrophia defectiva ATCC 49176.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Aerococcaceae; Abiotrophia.
OX NCBI_TaxID=592010 {ECO:0000313|EMBL:ESK66122.1, ECO:0000313|Proteomes:UP000019050};
RN [1] {ECO:0000313|EMBL:ESK66122.1, ECO:0000313|Proteomes:UP000019050}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 49176 {ECO:0000313|EMBL:ESK66122.1,
RC ECO:0000313|Proteomes:UP000019050};
RA Weinstock G., Sodergren E., Clifton S., Fulton L., Fulton B., Courtney L.,
RA Fronick C., Harrison M., Strong C., Farmer C., Delahaunty K., Markovic C.,
RA Hall O., Minx P., Tomlinson C., Mitreva M., Nelson J., Hou S., Wollam A.,
RA Pepin K.H., Johnson M., Bhonagiri V., Nash W.E., Warren W., Chinwalla A.,
RA Mardis E.R., Wilson R.K.;
RL Submitted (JUN-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ESK66122.1}.
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DR EMBL; ACIN03000003; ESK66122.1; -; Genomic_DNA.
DR STRING; 592010.GCWU000182_000464; -.
DR eggNOG; COG2373; Bacteria.
DR eggNOG; COG2931; Bacteria.
DR HOGENOM; CLU_000552_0_0_9; -.
DR OrthoDB; 2243937at2; -.
DR Proteomes; UP000019050; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR InterPro; IPR026395; CshA_fibril.
DR InterPro; IPR040683; CshA_NR2.
DR InterPro; IPR045474; GEVED.
DR InterPro; IPR019950; M_anchor.
DR InterPro; IPR005877; YSIRK_signal_dom.
DR NCBIfam; TIGR04225; CshA_fibril_rpt; 22.
DR NCBIfam; TIGR01168; YSIRK_signal; 1.
DR Pfam; PF18651; CshA_NR2; 1.
DR Pfam; PF19076; CshA_repeat; 22.
DR Pfam; PF20009; GEVED; 1.
DR Pfam; PF04650; YSIRK_signal; 1.
DR PRINTS; PR00015; GPOSANCHOR.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000019050};
KW Signal {ECO:0000256|ARBA:ARBA00022729};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 21..42
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 16..40
FT /note="YSIRK Gram-positive signal peptide"
FT /evidence="ECO:0000259|Pfam:PF04650"
FT DOMAIN 203..472
FT /note="Surface adhesin CshA non-repetitive"
FT /evidence="ECO:0000259|Pfam:PF18651"
FT DOMAIN 575..650
FT /note="GEVED"
FT /evidence="ECO:0000259|Pfam:PF20009"
FT DOMAIN 659..766
FT /note="CshA"
FT /evidence="ECO:0000259|Pfam:PF19076"
FT DOMAIN 794..903
FT /note="CshA"
FT /evidence="ECO:0000259|Pfam:PF19076"
FT DOMAIN 905..1004
FT /note="CshA"
FT /evidence="ECO:0000259|Pfam:PF19076"
FT DOMAIN 1007..1121
FT /note="CshA"
FT /evidence="ECO:0000259|Pfam:PF19076"
FT DOMAIN 1123..1222
FT /note="CshA"
FT /evidence="ECO:0000259|Pfam:PF19076"
FT DOMAIN 1224..1323
FT /note="CshA"
FT /evidence="ECO:0000259|Pfam:PF19076"
FT DOMAIN 1325..1424
FT /note="CshA"
FT /evidence="ECO:0000259|Pfam:PF19076"
FT DOMAIN 1426..1525
FT /note="CshA"
FT /evidence="ECO:0000259|Pfam:PF19076"
FT DOMAIN 1528..1626
FT /note="CshA"
FT /evidence="ECO:0000259|Pfam:PF19076"
FT DOMAIN 1628..1727
FT /note="CshA"
FT /evidence="ECO:0000259|Pfam:PF19076"
FT DOMAIN 1730..1828
FT /note="CshA"
FT /evidence="ECO:0000259|Pfam:PF19076"
FT DOMAIN 1830..1929
FT /note="CshA"
FT /evidence="ECO:0000259|Pfam:PF19076"
FT DOMAIN 1931..2030
FT /note="CshA"
FT /evidence="ECO:0000259|Pfam:PF19076"
FT DOMAIN 2033..2131
FT /note="CshA"
FT /evidence="ECO:0000259|Pfam:PF19076"
FT DOMAIN 2133..2232
FT /note="CshA"
FT /evidence="ECO:0000259|Pfam:PF19076"
FT DOMAIN 2235..2333
FT /note="CshA"
FT /evidence="ECO:0000259|Pfam:PF19076"
FT DOMAIN 2335..2434
FT /note="CshA"
FT /evidence="ECO:0000259|Pfam:PF19076"
FT DOMAIN 2436..2535
FT /note="CshA"
FT /evidence="ECO:0000259|Pfam:PF19076"
FT DOMAIN 2537..2636
FT /note="CshA"
FT /evidence="ECO:0000259|Pfam:PF19076"
FT DOMAIN 2638..2753
FT /note="CshA"
FT /evidence="ECO:0000259|Pfam:PF19076"
FT DOMAIN 2756..2844
FT /note="CshA"
FT /evidence="ECO:0000259|Pfam:PF19076"
FT DOMAIN 2849..2939
FT /note="CshA"
FT /evidence="ECO:0000259|Pfam:PF19076"
FT REGION 57..198
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 891..918
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 944..983
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1125..1153
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1222..1286
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1327..1354
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1425..1455
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1528..1552
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1627..1655
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1729..1759
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1829..1857
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1931..1959
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2034..2084
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2124..2163
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2333..2363
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2434..2462
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2538..2557
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 57..112
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 121..161
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1125..1144
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1222..1247
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1267..1286
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1327..1346
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1425..1451
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1627..1651
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1729..1752
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1829..1851
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1931..1952
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2034..2057
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2124..2159
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2333..2360
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2434..2461
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2538..2555
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2994 AA; 315608 MW; FF763D4CED628B5B CRC64;
MFSKNNRQMN QQKQGEKVTR YAIKKFSFGA ASVAVACGIY FANGAAVQAE SQDNVTTTSL
DHEVASETSH QPAVQAASPD QAADATPASS ASSDQASAPA ASESSAAESS SQKEEPANKE
DQAAQASSEN SATPAAPAQP AATSPATSSE QPTANTEVTQ PSRSRRVRRD ATPTGLRDGD
PNSTIAKPTL ADSEKKRPAD LMKQINWLDF SDPSSLTNLD ANGAFQVGTV YEKEISPGYR
IKLTVTSLKP FHSTEIYRDR VKGTEYKDSY DPNAKNTWLP YTGEYSDQQN KGDDYRPKII
GAPQNRWTAI KEQGIDTKGR KTQLQVPKNA ANYGVTFKVE ATYLGKPVKA TVVMADGEEA
NPGEYAIFTT NGQGWEHLAE WKRVSPNGTE ITETYAPIQP NTDGQYIGND GSGVHWYSYT
NPDQRTGGLG SQVFGPNTSK RNTVPIVMTR GASEVGIYIA SSGQQAAMIG FMVVDEGDAP
ESYGKAVHTI SGYDAETGAR NPQPYLGRVA ADIDTSSGGD WTHDDNTDHA DEGIKQLLPD
DLVNQTHNLF RADRLRDGNY SVRFHANANG NAKAYVRAWM DFNQNGKFDD NEASDFTEVT
GEGDFTVNFR NHPPMTNDQV NKIGMRIRIA LNQGDIEKPT GTAFSGEVED LEVLLTYPPK
GEKKETFGLQ DQQQKATLHF TPRGVDKNDE NAKAAIDTNK APIVLDNTGQ TLTPNGEGWY
TTTEGRYKVT ADGADVNVVF EPAAGFTGKA AGINIRRFDT NGSDTNWTAK NNSEAHVSDT
LNTMDARYVP NVLKHTENVS TDAQGLPQEK DIVFNDGDPA NTPVQPSASN PATFLDAEGN
PVSGTSIPAT SGGKEVGTFN LDPATGRVTF TPNKSFVGTV DPVNLQVNDA SGQPHRATYQ
PKVTPVVPTG QNASSEGIQG AEQSGNLVFT PGDSRVPIDE AVAPTFDNGK STKEVPGVGT
YTVDNTGRVT FQPLPGYTGR PNPETVKRVD KNGTEVTATY QADVKAATPT GQDTQTTGLQ
GQLQTSQLNF TPGQATVNNQ TQTVPLNPAG PQFVVDGQVQ QGNTLTVSDA SGKVQGTYTV
KPNGEISFQP APDFYGTPTP ARLRVTDSNG STADAVYQPN VTQVTPTSTN AESNGVQGQP
QKGTPTFKAG DPLVPLDDTK PMTFEDGSST KTVPNVGVYT INPDGSITFT PEKQYVGTPA
PVTVKRVDKN GTPVTATYTP TVTKVTPTST NDTSEGVQGQ PQKGTPTFTA GDPLVPLDDT
KPMTFEDGSS TKKVPNVGEY SINPDGSITF TPEKQYVGTP APVTVKRVDK NGTEVTATYT
PTVTKVTPIS TNSESSGIQG KPQKGTPTFT AGDPLVPLDD SKPMTFEDGS STKKVPNVGT
YVIESDGTIT FTPDKQYVGT PDPVTVKRVD KNGTEVTATY TPTVTKVTPT STDDTSEGVQ
GQPQKGTPTF SPGNPEVPID LDSPMTFEDG QPTKTVQGVG VYTINPDGSI TFTPDKQYVG
TPDPVVVKRV DKNGTEVTAK YTPTVTRVTP TSTNAESSGI QGQPQKGTPT FTEGNPLVPI
DDSKPMTFED GSSTKTVPNV GVYTINPDGS ITFTPDKQYV GTPAPVTVKR VDKNGTEVTA
TYTPTVTKVT PTSKDDTSTG VQGQPQTGTP VFTPGDKAVP IDLDSPMTFE DGQPTKTVPG
VGEYSINPDG SITFTPDKQY VGTPDPVVVK RVDKNGTEVT AKYTPTVTRV TPTSTNDTSE
GVQGQPQKGT PTFTAGDPLV PLDDTKPMTF EDGSSTKKVP NVGEYSINPD GSITFTPDKQ
YVGTPAPVTV KRVDKNGTEV TATYTPTVTK VTPTSKDDTS TGVQGIPQTG TPVFTPGDPA
VPIDLDSPMT FEDGQPKKIV PGVGEYSINP DGSITFTPDK QYVGTPAPVT VKRVDKNGTE
VTAQYTPTVT KVTPTSKDDT STGVQGVPQT GTPVFTPGDP AVPIDLDSPM TFEDGSSTKS
VPGVGEYSIN PDGTITFTPD KQYVGTPAPV MVKRVDKNGT PVTANYTPTV TRVTPTSQDA
ASTGAQGLPQ SGTPSFTPGD PAVPIDMDSP MTFDDGQTTK SVPGVGEYSI NPDGSITFTP
EKQYVGTPAA VVVKRVDKNG TPVTAQYTPT VTPVTPTSED VSSTGLQGQK QTGTPTFTPG
NPEVPMDDTV PMTFEDGSST KSVPGVGEYS INPDGSITFT PDKQFVGKPD PVRVKRVDKN
GTPVTADYQV EVTRVTPTST PATSTGLQGQ PQTGSPVFKE GAPEVPMDDT VPMTFEDGSS
TKTVPNVGVY TINPDGSITF TPDKQYVGTP DPVTVKRVDK NGTPVTATYT PTVTKVTPTS
TPATSTGLQG QPQTGSPSFT PGDPVVPMDD SVPMTFEDGS TTKSVPGVGE YSINPDGSIT
FTPDKQYVGT PDPVTVKRVD KNGTPVTATY TPTVTKVTPT STPATSTGAQ GLPQSGTPSF
TPGDPIVPMD DSVPMTFEDG SSTKSVPGVG EYSINPDGSI TFTPNKQFVG SPDPVTVKRV
DKNGTPVTAT YTPTVTKVTP TSTPATSTGA QGYKQSGKPV FTPGAALVPM DDSVPMTFED
GTTTKTVIGE GVYTIQADGS IEFVPEKTFT GQGSQLTVKR VDKNGTPVTA TYQATVVPVK
PGANDDYSSG VVNQAQTGQV KFMPGSANIN GTEQSVDLVP GSLKFVVNGQ AVADTTIPAL
DQDGKQVGTY SLAQDGTVTF TPNPGYVGQP VPARIQATDV NGTTAEATYS PVVNASVTSE
GMKGQSQSKL PDFKGQVDTK VPAYLEGGVT SVTVPGQGTY TVNPETGEVT FTPEPDFIGE
ASPITVIRRD VNGKELKIQY IPTVYGQVKT QDTTSTGYPG EKQTGTPVFE GDVDLTIPAT
FENGQTELTV PGEGTYVLNP DGSVTFTPEA GFLGQASGVT VVRVDRNGRK VTAQYVPTVV
PVPVAPSEPE VQTQGLLPAT GEAPDYSFFS GVALTILASV GLVATRKRQA TDED
//
