ID W1Q6S2_OGAPD Unreviewed; 431 AA.
AC W1Q6S2;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 13-SEP-2023, entry version 32.
DE RecName: Full=Fe2OG dioxygenase domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=HPODL_02486 {ECO:0000313|EMBL:ESW95838.1};
OS Ogataea parapolymorpha (strain ATCC 26012 / BCRC 20466 / JCM 22074 / NRRL
OS Y-7560 / DL-1) (Yeast) (Hansenula polymorpha).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Pichiaceae; Ogataea.
OX NCBI_TaxID=871575 {ECO:0000313|EMBL:ESW95838.1, ECO:0000313|Proteomes:UP000008673};
RN [1] {ECO:0000313|EMBL:ESW95838.1, ECO:0000313|Proteomes:UP000008673}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 26012 / BCRC 20466 / JCM 22074 / NRRL Y-7560 / DL-1
RC {ECO:0000313|Proteomes:UP000008673};
RX PubMed=24279325; DOI=10.1186/1471-2164-14-837;
RA Ravin N.V., Eldarov M.A., Kadnikov V.V., Beletsky A.V., Schneider J.,
RA Mardanova E.S., Smekalova E.M., Zvereva M.I., Dontsova O.A., Mardanov A.V.,
RA Skryabin K.G.;
RT "Genome sequence and analysis of methylotrophic yeast Hansenula polymorpha
RT DL1.";
RL BMC Genomics 14:837-837(2013).
RN [2] {ECO:0000313|Proteomes:UP000008673}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 26012 / BCRC 20466 / JCM 22074 / NRRL Y-7560 / DL-1
RC {ECO:0000313|Proteomes:UP000008673};
RA Ravin N.V., Mardanov A.V., Eldarov M.A., Kadnikov V.V., Beletsky A.V.,
RA Zvereva M.I., Smekalova E.M., Dontsova O.A., Skryabin K.G.;
RT "Genome sequence of the methylotrophic yeast Hansenula polymorpha DL1.";
RL Submitted (OCT-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ESW95838.1}.
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DR EMBL; AEOI02000010; ESW95838.1; -; Genomic_DNA.
DR RefSeq; XP_013932268.1; XM_014076793.1.
DR AlphaFoldDB; W1Q6S2; -.
DR STRING; 871575.W1Q6S2; -.
DR GeneID; 25771939; -.
DR KEGG; opa:HPODL_02486; -.
DR eggNOG; ENOG502QUQ4; Eukaryota.
DR HOGENOM; CLU_026011_0_0_1; -.
DR OMA; WHITSAF; -.
DR OrthoDB; 325143at2759; -.
DR Proteomes; UP000008673; Chromosome VII.
DR GO; GO:0051213; F:dioxygenase activity; IEA:InterPro.
DR GO; GO:0043130; F:ubiquitin binding; IEA:InterPro.
DR GO; GO:0006307; P:DNA dealkylation involved in DNA repair; IEA:InterPro.
DR GO; GO:0035552; P:oxidative single-stranded DNA demethylation; IEA:InterPro.
DR CDD; cd14279; CUE; 1.
DR Gene3D; 2.60.120.590; Alpha-ketoglutarate-dependent dioxygenase AlkB-like; 1.
DR InterPro; IPR027450; AlkB-like.
DR InterPro; IPR037151; AlkB-like_sf.
DR InterPro; IPR032854; ALKBH3.
DR InterPro; IPR003892; CUE.
DR InterPro; IPR005123; Oxoglu/Fe-dep_dioxygenase.
DR PANTHER; PTHR31212; ALPHA-KETOGLUTARATE-DEPENDENT DIOXYGENASE ALKB HOMOLOG 3; 1.
DR PANTHER; PTHR31212:SF4; ALPHA-KETOGLUTARATE-DEPENDENT DIOXYGENASE ALKB HOMOLOG 3; 1.
DR Pfam; PF13532; 2OG-FeII_Oxy_2; 1.
DR SUPFAM; SSF51197; Clavaminate synthase-like; 1.
DR PROSITE; PS51140; CUE; 1.
DR PROSITE; PS51471; FE2OG_OXY; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000008673}.
FT DOMAIN 2..45
FT /note="CUE"
FT /evidence="ECO:0000259|PROSITE:PS51140"
FT DOMAIN 229..335
FT /note="Fe2OG dioxygenase"
FT /evidence="ECO:0000259|PROSITE:PS51471"
SQ SEQUENCE 431 AA; 49514 MW; 623BEDE6FFD8C7EE CRC64;
METEQKLDTL QSQFPEVSKD VLLELLVAFD GSVKQTKLML EEQFGPREIK TEIKTEIKTE
IKGKFSGIKR KADSGTTANE YCSLTKKRTF PQRQTSFKVS KASANISTTL YNKEQIESMV
PYLRFYPNFL PNSLADSLLD ELLSKRATFK DKMFHIAGNE CHSNHQSTVF YDGDIPKQRY
DNGFYHNSKY MAQSFTGNIR TAKFLIEDQA NEVLATTKRH PLQVQSEWRA SLCVGNYFHT
NKNNLDWHSD RLTTIGPLPL ICSLTLGATR IFRIRKQYGE SPIYNIPLPH NSLLLMLPGT
QEEFKHCVPS LGNSLVARHP KANETRINLT LRMSRPHLLN NTPFCPVCKS AMTLRRMFKK
PASRGYYFWL CDGGYHSGKE CPGFYFANLS DIEKPHAKLY TRDVKHATRW LAEDDHEAKT
ATEFHMEDVK D
//
