ID W1QL40_OGAPD Unreviewed; 360 AA.
AC W1QL40;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE SubName: Full=Aryl-alcohol dehydrogenase {ECO:0000313|EMBL:ESX03500.1};
DE EC=1.1.1.- {ECO:0000313|EMBL:ESX03500.1};
GN ORFNames=HPODL_00007 {ECO:0000313|EMBL:ESX03500.1};
OS Ogataea parapolymorpha (strain ATCC 26012 / BCRC 20466 / JCM 22074 / NRRL
OS Y-7560 / DL-1) (Yeast) (Hansenula polymorpha).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Pichiaceae; Ogataea.
OX NCBI_TaxID=871575 {ECO:0000313|EMBL:ESX03500.1, ECO:0000313|Proteomes:UP000008673};
RN [1] {ECO:0000313|EMBL:ESX03500.1, ECO:0000313|Proteomes:UP000008673}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 26012 / BCRC 20466 / JCM 22074 / NRRL Y-7560 / DL-1
RC {ECO:0000313|Proteomes:UP000008673};
RX PubMed=24279325; DOI=10.1186/1471-2164-14-837;
RA Ravin N.V., Eldarov M.A., Kadnikov V.V., Beletsky A.V., Schneider J.,
RA Mardanova E.S., Smekalova E.M., Zvereva M.I., Dontsova O.A., Mardanov A.V.,
RA Skryabin K.G.;
RT "Genome sequence and analysis of methylotrophic yeast Hansenula polymorpha
RT DL1.";
RL BMC Genomics 14:837-837(2013).
RN [2] {ECO:0000313|Proteomes:UP000008673}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 26012 / BCRC 20466 / JCM 22074 / NRRL Y-7560 / DL-1
RC {ECO:0000313|Proteomes:UP000008673};
RA Ravin N.V., Mardanov A.V., Eldarov M.A., Kadnikov V.V., Beletsky A.V.,
RA Zvereva M.I., Smekalova E.M., Dontsova O.A., Skryabin K.G.;
RT "Genome sequence of the methylotrophic yeast Hansenula polymorpha DL1.";
RL Submitted (OCT-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ESX03500.1}.
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DR EMBL; AEOI02000001; ESX03500.1; -; Genomic_DNA.
DR RefSeq; XP_013936916.1; XM_014081441.1.
DR AlphaFoldDB; W1QL40; -.
DR STRING; 871575.W1QL40; -.
DR GeneID; 25769482; -.
DR KEGG; opa:HPODL_00007; -.
DR eggNOG; KOG1575; Eukaryota.
DR HOGENOM; CLU_023205_2_0_1; -.
DR OMA; MYREEYH; -.
DR OrthoDB; 5357470at2759; -.
DR Proteomes; UP000008673; Chromosome I.
DR GO; GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:UniProt.
DR CDD; cd19079; AKR_EcYajO-like; 1.
DR Gene3D; 3.20.20.100; NADP-dependent oxidoreductase domain; 1.
DR InterPro; IPR023210; NADP_OxRdtase_dom.
DR InterPro; IPR036812; NADP_OxRdtase_dom_sf.
DR PANTHER; PTHR43364:SF15; ARYL-ALCOHOL DEHYDROGENASE AAD16-RELATED; 1.
DR PANTHER; PTHR43364; NADH-SPECIFIC METHYLGLYOXAL REDUCTASE-RELATED; 1.
DR Pfam; PF00248; Aldo_ket_red; 1.
DR SUPFAM; SSF51430; NAD(P)-linked oxidoreductase; 1.
PE 4: Predicted;
KW Oxidoreductase {ECO:0000313|EMBL:ESX03500.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000008673}.
FT DOMAIN 30..348
FT /note="NADP-dependent oxidoreductase"
FT /evidence="ECO:0000259|Pfam:PF00248"
SQ SEQUENCE 360 AA; 40966 MW; 9467E585BC11D15A CRC64;
MPPKFNSFKW DTIPEDLYTR LGKSGLQISR IVLGCMSYGR KSWFDFVLED EDEVFTIMKK
AYDSGIRTFD TSCNYSNGFS EILVGKFLKK HNIDRRTVVI LSKCFFPPNE SDPDTNIIVP
GTAEGSEYIN RYGLSRTNIL DSVDKSIERL GTHIDVLQVH RFDTNTPIEE TMEALHDVVK
SGKVKYIGAS TMRAYQFVEM QHVAELHGWT KFISMQSYYS LFYREEEDEL IAYCKKTGVG
LIPYSPLAGG VLARPFDKMF NTTPRSSIGL SVAMFGLNEI TDKDKLLLSR IEELANKHRV
KMATVAIAWC LAKDHNPILG LNKVERIDDA IAAIKLKLTD EEVAYLDEPD VSRKLPNLYH
//
