ID W1TMN7_9ACTO Unreviewed; 262 AA.
AC W1TMN7;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 24-JAN-2024, entry version 35.
DE RecName: Full=CobW/HypB/UreG nucleotide-binding domain-containing protein {ECO:0000259|Pfam:PF02492};
GN ORFNames=Q618_VCMC00001G0463 {ECO:0000313|EMBL:ETI82882.1};
OS Varibaculum cambriense DORA_20.
OC Bacteria; Actinomycetota; Actinomycetes; Actinomycetales; Actinomycetaceae;
OC Varibaculum.
OX NCBI_TaxID=1403948 {ECO:0000313|EMBL:ETI82882.1, ECO:0000313|Proteomes:UP000018843};
RN [1] {ECO:0000313|EMBL:ETI82882.1, ECO:0000313|Proteomes:UP000018843}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DORA_20 {ECO:0000313|Proteomes:UP000018843};
RA Brown C.T., Sharon I., Thomas B.C., Castelle C.J., Morowitz M.J.,
RA Banfield J.F.;
RT "A Varibaculum cambriense genome reconstructed from a premature infant gut
RT community with otherwise low bacterial novelty that shifts toward anaerobic
RT metabolism during the third week of life.";
RL Submitted (DEC-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the SIMIBI class G3E GTPase family. HypB/HupM
CC subfamily. {ECO:0000256|ARBA:ARBA00006211}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ETI82882.1}.
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DR EMBL; AZMI01000001; ETI82882.1; -; Genomic_DNA.
DR AlphaFoldDB; W1TMN7; -.
DR STRING; 184870.HMPREF1862_00410; -.
DR PATRIC; fig|1403948.3.peg.898; -.
DR eggNOG; COG0378; Bacteria.
DR Proteomes; UP000018843; Unassembled WGS sequence.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0016151; F:nickel cation binding; IEA:InterPro.
DR GO; GO:0051604; P:protein maturation; IEA:InterPro.
DR CDD; cd05390; HypB; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR003495; CobW/HypB/UreG_dom.
DR InterPro; IPR004392; Hyd_mat_HypB.
DR InterPro; IPR027417; P-loop_NTPase.
DR NCBIfam; TIGR00073; hypB; 1.
DR PANTHER; PTHR30134:SF2; HYDROGENASE MATURATION FACTOR HYPB; 1.
DR PANTHER; PTHR30134; HYDROGENASE PROTEIN ASSEMBLY PROTEIN, NICKEL CHAPERONE; 1.
DR Pfam; PF02492; cobW; 1.
DR PIRSF; PIRSF005624; Ni-bind_GTPase; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nickel {ECO:0000256|ARBA:ARBA00022596};
KW Reference proteome {ECO:0000313|Proteomes:UP000018843};
KW Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT DOMAIN 77..242
FT /note="CobW/HypB/UreG nucleotide-binding"
FT /evidence="ECO:0000259|Pfam:PF02492"
FT REGION 1..30
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 262 AA; 29291 MW; 8D7CC588E30485F2 CRC64;
MGRFHRHDDG TVHSHEHGDH THHHDHGDYV ADPQVIGDHS GYDTEKERIE ILEDIYAEND
HLAEHNRQAF AEHNVKVVNL MSSPGSGKTT LLERTLAELQ GKMRIGIIEG DIETPLDADR
LRGYGAQISL LNTGQGFGGE CHLDAPMVHH TLDGLDLSQL DLVIIENVGN LVCPAEFDVG
ENAKAMVFSI TEGEDKPLKY PVMFRSVEIV VVNKMDLAPY LNFDMDRFRG YLKQVNPGVK
VVEVSAEKGQ GIDAWIQWLQ QL
//
