ID   W1TPA0_9ACTO            Unreviewed;       683 AA.
AC   W1TPA0;
DT   19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT   19-MAR-2014, sequence version 1.
DT   24-JAN-2024, entry version 28.
DE   RecName: Full=Glycoside hydrolase 35 catalytic domain-containing protein {ECO:0000259|Pfam:PF01301};
GN   ORFNames=Q618_VCMC00003G0346 {ECO:0000313|EMBL:ETI82044.1};
OS   Varibaculum cambriense DORA_20.
OC   Bacteria; Actinomycetota; Actinomycetes; Actinomycetales; Actinomycetaceae;
OC   Varibaculum.
OX   NCBI_TaxID=1403948 {ECO:0000313|EMBL:ETI82044.1, ECO:0000313|Proteomes:UP000018843};
RN   [1] {ECO:0000313|EMBL:ETI82044.1, ECO:0000313|Proteomes:UP000018843}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DORA_20 {ECO:0000313|Proteomes:UP000018843};
RA   Brown C.T., Sharon I., Thomas B.C., Castelle C.J., Morowitz M.J.,
RA   Banfield J.F.;
RT   "A Varibaculum cambriense genome reconstructed from a premature infant gut
RT   community with otherwise low bacterial novelty that shifts toward anaerobic
RT   metabolism during the third week of life.";
RL   Submitted (DEC-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the glycosyl hydrolase 35 family.
CC       {ECO:0000256|ARBA:ARBA00009809, ECO:0000256|RuleBase:RU003679}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:ETI82044.1}.
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DR   EMBL; AZMI01000003; ETI82044.1; -; Genomic_DNA.
DR   AlphaFoldDB; W1TPA0; -.
DR   STRING; 184870.HMPREF1862_00701; -.
DR   PATRIC; fig|1403948.3.peg.1853; -.
DR   eggNOG; COG1874; Bacteria.
DR   Proteomes; UP000018843; Unassembled WGS sequence.
DR   GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR   CDD; cd03143; A4_beta-galactosidase_middle_domain; 1.
DR   Gene3D; 3.20.20.80; Glycosidases; 1.
DR   Gene3D; 2.60.40.1180; Golgi alpha-mannosidase II; 1.
DR   InterPro; IPR031330; Gly_Hdrlase_35_cat.
DR   InterPro; IPR013780; Glyco_hydro_b.
DR   InterPro; IPR001944; Glycoside_Hdrlase_35.
DR   InterPro; IPR017853; Glycoside_hydrolase_SF.
DR   PANTHER; PTHR23421:SF165; BETA-GALACTOSIDASE; 1.
DR   PANTHER; PTHR23421; BETA-GALACTOSIDASE RELATED; 1.
DR   Pfam; PF01301; Glyco_hydro_35; 1.
DR   PRINTS; PR00742; GLHYDRLASE35.
DR   SUPFAM; SSF51445; (Trans)glycosidases; 1.
PE   3: Inferred from homology;
KW   Glycosidase {ECO:0000256|ARBA:ARBA00023295};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Reference proteome {ECO:0000313|Proteomes:UP000018843}.
FT   DOMAIN          17..126
FT                   /note="Glycoside hydrolase 35 catalytic"
FT                   /evidence="ECO:0000259|Pfam:PF01301"
SQ   SEQUENCE   683 AA;  76639 MW;  F06FB35A5F5F354F CRC64;
     MEKQTDNRPV SVGKSAFKVD GETVSLYGGA VHYWRLDRDK WDQILESVKG MGFNMISIYI
     PWEIHEVEKG VFDFSGNKDI DAFLTLCEEK DFRVIVRPGP QINSELTWFG YPKRILENER
     LQMRNAKGGR TVLTQVPKPI PAVNYAADEF YEETALWYDA ICEILARHCY PKGGIVAAQV
     DNEMAYFFCI NAYAADYSEE SLAQYRTFLL DKYGDLASIN KAYGTSYGSE GEIDAPRRFE
     GKDKHDIPVL ADWIEYREQY LIISMDRLAD MMRERGLDQI ALFHNYPHPL GPGGAASGFT
     TPFNIAKLEE KLDFVGFDIY SRKELYSHVK TVGSYVVGTS RFPYIPEFIA GVWPWYLNPG
     EIYDEEFVTK AALMQGIKGF SRYMLVERDR WLDSPIRRDG RVREDHEKMF SNANRMQSEN
     SFTSLRRDAK VLLLANREYD RLEAASVLVS FPGDFLETPS GFSEYANPLT ISEDNLGFDA
     PVQLEKSKAF GACFEALSAG GHDFVISDTD LDPARWGERS IIVLPTLDYL DAKIQQALVD
     FVAGGGCAVV GPKLPELDSL MNPCTILKDA VESGKGKWFV VKSGDDAASM LDKACAAADV
     AAVSKSDSRL DVVVHVDQSD DKRRVVFVAN PTAEAIDTRI ELPFEIEKAT ELWSGQPGTV
     QGSQLMASMP AYSINVYDCS LKN
//