ID   W1TT12_9ACTO            Unreviewed;       408 AA.
AC   W1TT12;
DT   19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT   19-MAR-2014, sequence version 1.
DT   24-JAN-2024, entry version 41.
DE   RecName: Full=Arginine deiminase {ECO:0008006|Google:ProtNLM};
GN   ORFNames=Q618_VCMC00001G0980 {ECO:0000313|EMBL:ETI83399.1};
OS   Varibaculum cambriense DORA_20.
OC   Bacteria; Actinomycetota; Actinomycetes; Actinomycetales; Actinomycetaceae;
OC   Varibaculum.
OX   NCBI_TaxID=1403948 {ECO:0000313|EMBL:ETI83399.1, ECO:0000313|Proteomes:UP000018843};
RN   [1] {ECO:0000313|EMBL:ETI83399.1, ECO:0000313|Proteomes:UP000018843}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DORA_20 {ECO:0000313|Proteomes:UP000018843};
RA   Brown C.T., Sharon I., Thomas B.C., Castelle C.J., Morowitz M.J.,
RA   Banfield J.F.;
RT   "A Varibaculum cambriense genome reconstructed from a premature infant gut
RT   community with otherwise low bacterial novelty that shifts toward anaerobic
RT   metabolism during the third week of life.";
RL   Submitted (DEC-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the arginine deiminase family.
CC       {ECO:0000256|ARBA:ARBA00010206}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:ETI83399.1}.
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DR   EMBL; AZMI01000001; ETI83399.1; -; Genomic_DNA.
DR   AlphaFoldDB; W1TT12; -.
DR   STRING; 184870.HMPREF1862_01265; -.
DR   PATRIC; fig|1403948.3.peg.1423; -.
DR   eggNOG; COG2235; Bacteria.
DR   Proteomes; UP000018843; Unassembled WGS sequence.
DR   GO; GO:0016990; F:arginine deiminase activity; IEA:InterPro.
DR   GO; GO:0006527; P:arginine catabolic process; IEA:InterPro.
DR   Gene3D; 1.10.3930.10; Arginine deiminase; 1.
DR   InterPro; IPR003876; Arg_deiminase.
DR   PANTHER; PTHR47271; ARGININE DEIMINASE; 1.
DR   PANTHER; PTHR47271:SF2; ARGININE DEIMINASE; 1.
DR   Pfam; PF02274; ADI; 1.
DR   PIRSF; PIRSF006356; Arg_deiminase; 1.
DR   PRINTS; PR01466; ARGDEIMINASE.
DR   SUPFAM; SSF55909; Pentein; 1.
PE   3: Inferred from homology;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Reference proteome {ECO:0000313|Proteomes:UP000018843}.
FT   ACT_SITE        397
FT                   /note="Amidino-cysteine intermediate"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR006356-1"
SQ   SEQUENCE   408 AA;  45317 MW;  00378BEFC90B2E10 CRC64;
     MMRGVWSEVG KLEKVLVHRP GSEIDRLTPS NREELLFDDI LWLEKAREDH DTFSATLSSQ
     GAQVVYLRDL LAETLELASA RKWLLEQTVD DRHFGVALSA PLREYLAEQE SRKLAQIMIS
     GLTRAEIESQ LGAVASTVLA RVETEDFILA PLPNHLFTRD TSAWIGRGVM LSAMKKTARR
     RETLNLQAIY RFHPDFSDNL TQFGAGVADT PASTEGGDVE ILSENSVLVG ISERTSPAGF
     ERLASRLLRD SSSSIEMVTG LLMPMERAQM HLDTVLTMIN RDTFYKYKKL GMLASVTARR
     GADGQISWQM HPEAEMHEIL AQAAGVSAVN ILQTPQSDSG AERGQWNDAC NLLALRENVV
     TSYDRNWQTI DYLRSQGVKV LEVPSAELGR GRGGPRCMTC PLSRAAVE
//