ID   W1YA44_9ZZZZ            Unreviewed;        75 AA.
AC   W1YA44;
DT   19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT   19-MAR-2014, sequence version 1.
DT   27-MAR-2024, entry version 12.
DE   SubName: Full=Homocysteine S-methyltransferase {ECO:0000313|EMBL:ETJ39367.1};
DE   Flags: Fragment;
GN   ORFNames=Q604_UNBC06772G0001 {ECO:0000313|EMBL:ETJ39367.1};
OS   human gut metagenome.
OC   unclassified sequences; metagenomes; organismal metagenomes.
OX   NCBI_TaxID=408170 {ECO:0000313|EMBL:ETJ39367.1};
RN   [1] {ECO:0000313|EMBL:ETJ39367.1}
RP   NUCLEOTIDE SEQUENCE.
RA   Brown C.T., Sharon I., Thomas B.C., Castelle C.J., Morowitz M.J.,
RA   Banfield J.F.;
RT   "A Varibaculum cambriense genome reconstructed from a premature infant gut
RT   community with otherwise low bacterial novelty that shifts toward anaerobic
RT   metabolism during the third week of life.";
RL   Submitted (DEC-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:ETJ39367.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AZMM01006772; ETJ39367.1; -; Genomic_DNA.
DR   AlphaFoldDB; W1YA44; -.
DR   GO; GO:0031419; F:cobalamin binding; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.280; Cobalamin-binding domain; 1.
DR   InterPro; IPR006158; Cobalamin-bd.
DR   InterPro; IPR036724; Cobalamin-bd_sf.
DR   PANTHER; PTHR45833; METHIONINE SYNTHASE; 1.
DR   PANTHER; PTHR45833:SF1; METHIONINE SYNTHASE; 1.
DR   Pfam; PF02310; B12-binding; 1.
DR   SUPFAM; SSF52242; Cobalamin (vitamin B12)-binding domain; 1.
DR   PROSITE; PS51332; B12_BINDING; 1.
PE   4: Predicted;
KW   Cobalt {ECO:0000256|ARBA:ARBA00023285};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Methyltransferase {ECO:0000313|EMBL:ETJ39367.1};
KW   Transferase {ECO:0000313|EMBL:ETJ39367.1}.
FT   DOMAIN          1..75
FT                   /note="B12-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS51332"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:ETJ39367.1"
FT   NON_TER         75
FT                   /evidence="ECO:0000313|EMBL:ETJ39367.1"
SQ   SEQUENCE   75 AA;  7900 MW;  A159F72FEE9CBBB7 CRC64;
     VVVATVKGDI HDLGKNIVAA LLENNGYKIV DLGKDVDPEV IVQAIKDNKA ALVGICSLMT
     TTMPQIDNTI AAIRA
//