ID W2E5X3_9BACL Unreviewed; 606 AA.
AC W2E5X3;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 27-MAR-2024, entry version 42.
DE SubName: Full=Histidine kinase {ECO:0000313|EMBL:ETK27033.1};
GN ORFNames=ERIC1_1c04710 {ECO:0000313|EMBL:ETK27033.1};
OS Paenibacillus larvae subsp. larvae DSM 25719.
OC Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae; Paenibacillus.
OX NCBI_TaxID=697286 {ECO:0000313|EMBL:ETK27033.1, ECO:0000313|Proteomes:UP000018834};
RN [1] {ECO:0000313|EMBL:ETK27033.1, ECO:0000313|Proteomes:UP000018834}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 25719 {ECO:0000313|EMBL:ETK27033.1,
RC ECO:0000313|Proteomes:UP000018834};
RX PubMed=24599066;
RA Djukic M., Brzuszkiewicz E., Funfhaus A., Voss J., Gollnow K., Poppinga L.,
RA Liesegang H., Garcia-Gonzalez E., Genersch E., Daniel R.;
RT "How to Kill the Honey Bee Larva: Genomic Potential and Virulence
RT Mechanisms of Paenibacillus larvae.";
RL PLoS ONE 9:E90914-E90914(2014).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ETK27033.1}.
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DR EMBL; ADFW01000001; ETK27033.1; -; Genomic_DNA.
DR AlphaFoldDB; W2E5X3; -.
DR PATRIC; fig|697286.3.peg.534; -.
DR Proteomes; UP000018834; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd06225; HAMP; 1.
DR Gene3D; 6.10.340.10; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR InterPro; IPR003660; HAMP_dom.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR010559; Sig_transdc_His_kin_internal.
DR PANTHER; PTHR34220; SENSOR HISTIDINE KINASE YPDA; 1.
DR PANTHER; PTHR34220:SF7; SENSOR HISTIDINE KINASE YPDA; 1.
DR Pfam; PF00672; HAMP; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF06580; His_kinase; 1.
DR SMART; SM00304; HAMP; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF158472; HAMP domain-like; 1.
DR PROSITE; PS50885; HAMP; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:ETK27033.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 292..313
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 313..365
FT /note="HAMP"
FT /evidence="ECO:0000259|PROSITE:PS50885"
SQ SEQUENCE 606 AA; 69807 MW; 41C61552045FA2A8 CRC64;
MRFFRWLYNQ YIRSTQIRLT SSFLLVLLPL VFVSLYANDR SRQIVLDQTL SQAQNNLDSQ
AAHMDLTLKN VEELSRMIAL DKTLLQMLDQ AGPELTPQSI IQFTEILNRL WHVTSISQIL
SEISVYHAKS GTVVSTKNGA KRITLADQKE VYEQLALSSG IGGTYVLPSQ KIMKDTTFRE
LSGSEMVSLV RTMDLSAWSK HSNLLIVTLN KKKLNELILS ALPSAGTHLY LFEKDGNIIT
GSDQPDSGTG FINVKKEGML RIQAELPSYK WSLVMLQPEQ EIYGQTGVVR TYTYLIIVIS
VLLSLILSWW VFIRIASPLD RLSYGMKELS SGNYDLRLDT TRKDEFGYLM KTYNKMARHQ
KHLIEDYYEQ QLRLANTELK FLQSQINPHF LYNTLDSIYW MAKNYEAEEI SEMVLNLSRF
FRLSLNKGKE AFTVEETISH LHYYIRVQQI RFLDSFTVSY QIQEESKTIP VYKLLLQPLV
ENALLHGLER KQEGGELIIS SYLEEEYLVL SVQDNGDGIN RERLDYIQQE LGSLAQNKAA
ILHDMERTIQ DLYGLRNVLI RLKMMYGPKA DLQLESEEGV ETRITLFIPL DSCKSEFIMD
GKERLA
//
