ID W2ED43_9BACL Unreviewed; 146 AA.
AC W2ED43;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE RecName: Full=Mannitol-specific phosphotransferase enzyme IIA component {ECO:0000256|ARBA:ARBA00014783};
DE AltName: Full=EIIA {ECO:0000256|ARBA:ARBA00030956};
DE AltName: Full=EIII {ECO:0000256|ARBA:ARBA00030962};
DE AltName: Full=PTS system mannitol-specific EIIA component {ECO:0000256|ARBA:ARBA00029908};
GN Name=mtlF {ECO:0000313|EMBL:ETK29539.1};
GN ORFNames=ERIC1_1c30960 {ECO:0000313|EMBL:ETK29539.1};
OS Paenibacillus larvae subsp. larvae DSM 25719.
OC Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae; Paenibacillus.
OX NCBI_TaxID=697286 {ECO:0000313|EMBL:ETK29539.1, ECO:0000313|Proteomes:UP000018834};
RN [1] {ECO:0000313|EMBL:ETK29539.1, ECO:0000313|Proteomes:UP000018834}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 25719 {ECO:0000313|EMBL:ETK29539.1,
RC ECO:0000313|Proteomes:UP000018834};
RX PubMed=24599066;
RA Djukic M., Brzuszkiewicz E., Funfhaus A., Voss J., Gollnow K., Poppinga L.,
RA Liesegang H., Garcia-Gonzalez E., Genersch E., Daniel R.;
RT "How to Kill the Honey Bee Larva: Genomic Potential and Virulence
RT Mechanisms of Paenibacillus larvae.";
RL PLoS ONE 9:E90914-E90914(2014).
CC -!- FUNCTION: The phosphoenolpyruvate-dependent sugar phosphotransferase
CC system (sugar PTS), a major carbohydrate active transport system,
CC catalyzes the phosphorylation of incoming sugar substrates
CC concomitantly with their translocation across the cell membrane. The
CC enzyme II CmtAB PTS system is involved in D-mannitol transport.
CC {ECO:0000256|ARBA:ARBA00002434}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ETK29539.1}.
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DR EMBL; ADFW01000001; ETK29539.1; -; Genomic_DNA.
DR RefSeq; WP_023485400.1; NZ_ADFW01000001.1.
DR AlphaFoldDB; W2ED43; -.
DR GeneID; 64217400; -.
DR PATRIC; fig|697286.3.peg.3324; -.
DR OrthoDB; 1640042at2; -.
DR Proteomes; UP000018834; Unassembled WGS sequence.
DR GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR GO; GO:0009401; P:phosphoenolpyruvate-dependent sugar phosphotransferase system; IEA:UniProtKB-KW.
DR CDD; cd00211; PTS_IIA_fru; 1.
DR InterPro; IPR016152; PTrfase/Anion_transptr.
DR InterPro; IPR002178; PTS_EIIA_type-2_dom.
DR PANTHER; PTHR30181; MANNITOL PERMEASE IIC COMPONENT; 1.
DR PANTHER; PTHR30181:SF2; PTS SYSTEM MANNITOL-SPECIFIC EIICBA COMPONENT; 1.
DR Pfam; PF00359; PTS_EIIA_2; 1.
DR SUPFAM; SSF55804; Phoshotransferase/anion transport protein; 1.
DR PROSITE; PS51094; PTS_EIIA_TYPE_2; 1.
DR PROSITE; PS00372; PTS_EIIA_TYPE_2_HIS; 1.
PE 4: Predicted;
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Phosphotransferase system {ECO:0000256|ARBA:ARBA00022683};
KW Sugar transport {ECO:0000256|ARBA:ARBA00022597};
KW Transferase {ECO:0000313|EMBL:ETK29539.1};
KW Transport {ECO:0000256|ARBA:ARBA00022597}.
FT DOMAIN 4..144
FT /note="PTS EIIA type-2"
FT /evidence="ECO:0000259|PROSITE:PS51094"
SQ SEQUENCE 146 AA; 15773 MW; A21D48235A0412D3 CRC64;
MTQTILTADK IKLDAKPATK KEAITMAGQL LVQAGCVSED YIQSMMEREE LQTTYMGFGV
AIPHGTKEAK TFIRSTGISV VQVREGVDFG NGNVAKILIG IAAVGDEHLD IIQNLALLIS
EEENVDKLVH ADTAKAVIDM IEQGDE
//
