ID   W2H232_PHYPR            Unreviewed;      1024 AA.
AC   W2H232;
DT   19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT   19-MAR-2014, sequence version 1.
DT   27-MAR-2024, entry version 33.
DE   RecName: Full=Vacuolar protein sorting-associated protein 54 {ECO:0000256|ARBA:ARBA00017665};
GN   ORFNames=L915_06610 {ECO:0000313|EMBL:ETK89298.1};
OS   Phytophthora parasitica (Potato buckeye rot agent).
OC   Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC   Phytophthora.
OX   NCBI_TaxID=4792 {ECO:0000313|EMBL:ETK89298.1};
RN   [1] {ECO:0000313|EMBL:ETK89298.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CJ02B3 {ECO:0000313|EMBL:ETK89298.1};
RG   The Broad Institute Genomics Platform;
RA   Russ C., Tyler B., Panabieres F., Shan W., Tripathy S., Grunwald N.,
RA   Machado M., Johnson C.S., Arredondo F., Hong C., Coffey M., Young S.K.,
RA   Zeng Q., Gargeya S., Fitzgerald M., Abouelleil A., Alvarado L.,
RA   Chapman S.B., Gainer-Dewar J., Goldberg J., Griggs A., Gujja S., Hansen M.,
RA   Howarth C., Imamovic A., Ireland A., Larimer J., McCowan C., Murphy C.,
RA   Pearson M., Poon T.W., Priest M., Roberts A., Saif S., Shea T., Sykes S.,
RA   Wortman J., Nusbaum C., Birren B.;
RT   "The Genome Sequence of Phytophthora parasitica CJ02B3.";
RL   Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Golgi apparatus, trans-Golgi network
CC       {ECO:0000256|ARBA:ARBA00004601}.
CC   -!- SIMILARITY: Belongs to the VPS54 family.
CC       {ECO:0000256|ARBA:ARBA00009150}.
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DR   EMBL; KI685681; ETK89298.1; -; Genomic_DNA.
DR   AlphaFoldDB; W2H232; -.
DR   EnsemblProtists; ETK89298; ETK89298; L915_06610.
DR   VEuPathDB; FungiDB:PPTG_02827; -.
DR   Proteomes; UP000053236; Unassembled WGS sequence.
DR   GO; GO:0005829; C:cytosol; IEA:GOC.
DR   GO; GO:0000938; C:GARP complex; IEA:InterPro.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0042147; P:retrograde transport, endosome to Golgi; IEA:InterPro.
DR   Gene3D; 1.20.1280.130; -; 1.
DR   Gene3D; 6.10.250.860; -; 1.
DR   InterPro; IPR039745; Vps54.
DR   InterPro; IPR012501; Vps54_C.
DR   InterPro; IPR019515; VPS54_N.
DR   PANTHER; PTHR12965; VACUOLAR PROTEIN SORTING 54; 1.
DR   PANTHER; PTHR12965:SF0; VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 54; 1.
DR   Pfam; PF07928; Vps54; 1.
DR   Pfam; PF10475; Vps54_N; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW   Golgi apparatus {ECO:0000256|ARBA:ARBA00023034};
KW   Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW   Transport {ECO:0000256|ARBA:ARBA00022448}.
FT   DOMAIN          238..426
FT                   /note="Vacuolar protein sorting-associated protein 54 N-
FT                   terminal"
FT                   /evidence="ECO:0000259|Pfam:PF10475"
FT   DOMAIN          775..905
FT                   /note="Vacuolar protein sorting-associated protein 54 C-
FT                   terminal"
FT                   /evidence="ECO:0000259|Pfam:PF07928"
FT   REGION          1..24
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          45..133
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          436..457
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          577..619
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        47..61
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        97..126
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        437..457
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        585..617
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1024 AA;  114237 MW;  1DF7EC0C14DE5625 CRC64;
     MEQRHDGGKK PLGGLSPRGL LKRGWNGVTS PLNALKDSVV AAATPRSVAA TPTSRMTLPS
     PTEYPSLFDV RGPSSTRSAD GATIFSHKHE IEARMPQSAR ESSSSTRTGS WGSSGRTGSS
     SGGWPEERLN DAQGEEERAY LSVCHHNLHS VLTNPKVNNW GGALLDAFYP TLDVDITLAP
     FPGLADVSTR DFQPYLRQFG TNAAKYEENH AKPVSEQLSS SNVPSISVAD EDVTKCLDVV
     PNLFFRPDFD LTDPNTFEEV MNMPNATSLQ EELTTYLDRV EFTLLRQVSS RSDRFFEASA
     DQEVMKQSIK VACDQVATLR KTMDRLRSLL ADKTLDIVSL HRRQKRIKEL HDLVTMVEEV
     KSAESAVEAL VQCQDYTNAL NLIESSQTLL REHLQGIHGL SSLNEKFRGY HGFISTQISQ
     RFISVITSPE WTFQDEEESA YSNKKRQNSL GDEKDTVQQE TKRLVDVLFR LDALEDTVKT
     YLDQLNEEIR VVVKTVVTET IAVSSSSKNS SGSDAGASSG SESKVSIQLR ALTSDEFLQC
     VQMIFEHLLM VLKRAVVVQG ILVKSMQTKI NEATEEENRL KAAAGNEGKS SSTEGSKTGE
     GASPEGWSPS GNASDDQKTL GDWKKKTRCA KVIREIDEVV RKTCEFSQRS VSNLFAVRKE
     VQAVYTMPQL RKLYDTTMDF VVSLEKLTGK TDYTLRGALF SQLKLFLEKY HQTQVTKLVS
     TLDHELWKNT EISETRHKSL DDLSSGRGVA LLLSDDREIA GETAPPRKMV SICGKSFRVV
     WSVLLMLEIV MNYMSCAANF PVLATDVLQR SIEIFRLFNS RTTQLVLGAG AMQIARLKSI
     SARHLALASQ SLELSMTLIP HIKAALAAHF TDRQKLLLDE FDRVLRDYAE HNEKIFSKFT
     SIVEDQIMKR FLENVATEVD YDSTSLSVPT NPMRGITQST LKLHGVLHPV LSPPQMKDVM
     SRVFDMFTQK LPECFKLVQP RTAAGKERVV NDIEVFVQSF KEVTELTFDG SALLKHFKNA
     YNVS
//