ID W2IG52_PHYPR Unreviewed; 454 AA.
AC W2IG52;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE RecName: Full=Histidine acid phosphatase {ECO:0008006|Google:ProtNLM};
GN ORFNames=L916_14913 {ECO:0000313|EMBL:ETL32517.1};
OS Phytophthora parasitica (Potato buckeye rot agent).
OC Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC Phytophthora.
OX NCBI_TaxID=4792 {ECO:0000313|EMBL:ETL32517.1};
RN [1] {ECO:0000313|EMBL:ETL32517.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CJ05E6 {ECO:0000313|EMBL:ETL32517.1};
RG The Broad Institute Genomics Platform;
RA Russ C., Tyler B., Panabieres F., Shan W., Tripathy S., Grunwald N.,
RA Machado M., Johnson C.S., Arredondo F., Hong C., Coffey M., Young S.K.,
RA Zeng Q., Gargeya S., Fitzgerald M., Abouelleil A., Alvarado L.,
RA Chapman S.B., Gainer-Dewar J., Goldberg J., Griggs A., Gujja S., Hansen M.,
RA Howarth C., Imamovic A., Ireland A., Larimer J., McCowan C., Murphy C.,
RA Pearson M., Poon T.W., Priest M., Roberts A., Saif S., Shea T., Sykes S.,
RA Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Phytophthora parasitica CJ05E6.";
RL Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; KI674838; ETL32517.1; -; Genomic_DNA.
DR AlphaFoldDB; W2IG52; -.
DR EnsemblProtists; ETL32517; ETL32517; L916_14913.
DR VEuPathDB; FungiDB:PPTG_04529; -.
DR Proteomes; UP000053864; Unassembled WGS sequence.
DR GO; GO:0016791; F:phosphatase activity; IEA:InterPro.
DR CDD; cd07061; HP_HAP_like; 1.
DR Gene3D; 3.40.50.1240; Phosphoglycerate mutase-like; 1.
DR InterPro; IPR033379; Acid_Pase_AS.
DR InterPro; IPR000560; His_Pase_clade-2.
DR InterPro; IPR029033; His_PPase_superfam.
DR InterPro; IPR016274; Histidine_acid_Pase_euk.
DR PANTHER; PTHR20963:SF18; ACID PHOSPHATASE PHO11-RELATED; 1.
DR PANTHER; PTHR20963; MULTIPLE INOSITOL POLYPHOSPHATE PHOSPHATASE-RELATED; 1.
DR Pfam; PF00328; His_Phos_2; 1.
DR PIRSF; PIRSF000894; Acid_phosphatase; 1.
DR SUPFAM; SSF53254; Phosphoglycerate mutase-like; 1.
DR PROSITE; PS00616; HIS_ACID_PHOSPHAT_1; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|PIRSR:PIRSR000894-2};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..19
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 20..454
FT /note="Histidine acid phosphatase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004817489"
FT ACT_SITE 65
FT /note="Nucleophile"
FT /evidence="ECO:0000256|PIRSR:PIRSR000894-1"
FT ACT_SITE 330
FT /note="Proton donor"
FT /evidence="ECO:0000256|PIRSR:PIRSR000894-1"
FT DISULFID 54..378
FT /evidence="ECO:0000256|PIRSR:PIRSR000894-2"
FT DISULFID 203..429
FT /evidence="ECO:0000256|PIRSR:PIRSR000894-2"
FT DISULFID 252..267
FT /evidence="ECO:0000256|PIRSR:PIRSR000894-2"
FT DISULFID 398..406
FT /evidence="ECO:0000256|PIRSR:PIRSR000894-2"
SQ SEQUENCE 454 AA; 50536 MW; CD62A0BE6C6385B9 CRC64;
MKTVSALLPV LLMAHTAQAY SEGFDLTDHT SQLNFYHQAA TDLTAEQVAL DETCEVDQVH
MIMRHGTRYP SSGSYNGIKS FAETVTEYLS WPNMSDTMAN ELKFLKTWNL TDLIPNPEIE
VENITALGLQ EAYDVGSTFR TKYAHLYNTK ETVWSNAKER VVRTAKSFMN GFHGENWNSN
LLVQVNNTDE TLGGDTLTPI DTCPNFEGDE SSAQTAFAEA TGWQTALAER LESLWPGFGF
STGVALTVMD LCMYQRNFLG KDHLEFCQIF TDDEWEHYGY HKDLGYYYGS GYGVALAPTV
GFPYAEAVTR LLNETETTYC QKIFVAFSQD TQLNAMYSGF GLNYDETYQT DAINATRNFR
SSRVVAMGSR MVTERITCNG ESYVRFNINE QVAPLPGCQS GPGLTCPLAA FVQYMETRKT
AVGDFVTECA STGGSSELTI FENPVMNQCA VTAC
//
