ID   W2J6S5_PHYPR            Unreviewed;      1194 AA.
AC   W2J6S5;
DT   19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT   19-MAR-2014, sequence version 1.
DT   24-JAN-2024, entry version 28.
DE   RecName: Full=tRNA ligase phosphodiesterase domain-containing protein {ECO:0000259|Pfam:PF08302};
GN   ORFNames=L916_06984 {ECO:0000313|EMBL:ETL42145.1};
OS   Phytophthora parasitica (Potato buckeye rot agent).
OC   Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC   Phytophthora.
OX   NCBI_TaxID=4792 {ECO:0000313|EMBL:ETL42145.1, ECO:0000313|Proteomes:UP000053864};
RN   [1] {ECO:0000313|EMBL:ETL42145.1, ECO:0000313|Proteomes:UP000053864}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CJ05E6 {ECO:0000313|EMBL:ETL42145.1,
RC   ECO:0000313|Proteomes:UP000053864};
RG   The Broad Institute Genomics Platform;
RA   Russ C., Tyler B., Panabieres F., Shan W., Tripathy S., Grunwald N.,
RA   Machado M., Johnson C.S., Arredondo F., Hong C., Coffey M., Young S.K.,
RA   Zeng Q., Gargeya S., Fitzgerald M., Abouelleil A., Alvarado L.,
RA   Chapman S.B., Gainer-Dewar J., Goldberg J., Griggs A., Gujja S., Hansen M.,
RA   Howarth C., Imamovic A., Ireland A., Larimer J., McCowan C., Murphy C.,
RA   Pearson M., Poon T.W., Priest M., Roberts A., Saif S., Shea T., Sykes S.,
RA   Wortman J., Nusbaum C., Birren B.;
RT   "The Genome Sequence of Phytophthora parasitica CJ05E6.";
RL   Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; KI672393; ETL42145.1; -; Genomic_DNA.
DR   AlphaFoldDB; W2J6S5; -.
DR   EnsemblProtists; ETL42145; ETL42145; L916_06984.
DR   VEuPathDB; FungiDB:PPTG_09748; -.
DR   Proteomes; UP000053864; Unassembled WGS sequence.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0003972; F:RNA ligase (ATP) activity; IEA:InterPro.
DR   GO; GO:0006388; P:tRNA splicing, via endonucleolytic cleavage and ligation; IEA:InterPro.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR026302; NEDD4_b_p2.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR015965; tRNA_lig_PDEase.
DR   PANTHER; PTHR13308:SF40; SMR DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR13308; UNCHARACTERIZED; 1.
DR   Pfam; PF13671; AAA_33; 1.
DR   Pfam; PF08302; tRNA_lig_CPD; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE   4: Predicted;
FT   DOMAIN          492..552
FT                   /note="tRNA ligase phosphodiesterase"
FT                   /evidence="ECO:0000259|Pfam:PF08302"
FT   REGION          1..35
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        7..23
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1194 AA;  132886 MW;  8639783AC7AE94EE CRC64;
     MAWGKNRRAS SGNSSSRPSS SASRGGRRPP GEPTEQDIAR NIQRSAVRVR VLLTLSDVQD
     ESELLRDLLT AFEQNLEAQR GNGVTQCHRV RVELLECGLN SWQNLVELQR VLAGLKRPIE
     YGEEQQLMAK TTLRHDSKYD EWTLSLGFTR ASEDALWRFA SNLMLRLKSC GVPSKVLLST
     DRLVVRLASA FVEWGNLEIG KYQWEGKQAW SQLVVEVPGE EREEIQRVFL PPISDVARDP
     LTELRYPELV PVVDDMLSSK DTGKPVVVIL RGIPGSGKST LGREIEAICH HRGVALTACS
     ADFFFETPRG YVFDVRKLGA AHSKCKGDFT RAVQGGIPRN ISDRSYHQHV VLVDNTSTQR
     WEYEPYEDIA KSHGSRVHIV EMKCADALMA FRMGQRNSHG VPPDKVVSMF MRWEDDARAH
     CFTPQFEHAR LTANPLSDGD VGGLTYLGLF LNDDTQQKML SQIPLVHPNR LADHVTLFYR
     PNKQYTRNAE LGAPFTVRAI EVVQDDQAQT LRVELDERLP LQVRNKIPHI TMSTKDGVSA
     SYSNDLLESK SAKRTMLNPP IEFTMRLGAA LVIQNQRVIT TSSPFAVDTS CCSKKEMSTP
     NTNGDKEDKV ASATSRLFVL YVNEGDMLQD SEEDTTKLLW RVQIMHHMGS SCKVRGLLCV
     QRYEESSSAS VATTLSSIQD HFLFSSTLYF DDVIMLPQHP SFPGFEKAIS SYVAAAGVGL
     VNHLTLMTSV EESIQWPICE MESLHEASLN VVRFGHATQS ISALPPTCPT ILSALDLLGS
     NIQEEVRSAI LGGVNAVNDA WVCVLGAEDR QAVQRIDTTI PGLSSSVVEL YLMLPSGTAA
     SEVEVLKTKL LTVLEATPNV HRMLRSCTSD QFYFNMCSLS SYTPHFCVQM ARQQEESDNP
     VTNTAAQLKF CEHQLKMSHE ACDVEAYSVL VALLRAILLG RCSNDLPTKC RLSTLINLVS
     ERLVLHYVSS IDDVNPTADD VTSGRIITTL YSMLTYLSKL DPAEWAATFG DSILALQGNE
     KARAAWREAM DTLMQSCAAV MTSHCCVSDD SKSATQLNPN DHLRVVVALM KTDNMRVHEI
     RTRTYIEMSS RSAWSPLHSL ACCDKLRSVA AMVVPQDDDE HNGDSEFFSC APSLVARRVD
     VATSSLDLLR NVLEKLHALE ATEWRDSEGA LSGDYVIRRA ETDEEVLIDL KRSS
//